Mass Spectrometry of Fatty Acid Derivatives

These pages are tutorials that deal with the application of mass spectrometry (MS) with electron-impact ionization, and linked to gas chromatography (GC), for the determination of the structures of fatty acids. They tend to be largely practical as opposed to mechanistic accounts. Although methyl esters are used almost universally for GC separations and often for MS, they afford limited structural information only. On the other hand, certain nitrogen-containing derivatives, especially pyrrolidides, 4,4‑dimethyloxazoline (DMOX) derivatives and 3‑pyridylcarbinol ('picolinyl') esters, give much more specific data as discussed in the attached web pages in which more than 735 mass spectra are illustrated (not counting the Archive sections with these and a further 1500 spectra). Spectra of some selected other lipids are also discussed. Whenever new information and mass spectra become available, these web pages will be updated.

Recommended Book: Christie, W.W. and Han, X. Lipid Analysis - Isolation, Separation, Identification and Lipidomic Analysis (4th edition), 446 pages (Oily Press, Woodhead Publishing and now Elsevier) (2010) - at Science Direct.

Credits/disclaimer/contact Updated: June 10th, 2021 Author: William W. Christie LipidWeb icon