Lipid Essentials Literature - Highlights - 2025
This list was created by means of a weekly literature search with a highly subjective scan to select those papers that appeared helpful to me for updating the Lipid Essentials or Blog pages on this site. They are mainly review articles dealing with the chemistry, occurrence and biochemistry of lipids, and the nutritional/clinical literature is under-represented here. Please note that I may only select references from journals to which I have direct access, or will have access after a period specified by the journal (usually 6 to 24 months). Some papers in press may be listed here without the full citation, but the DOI address should still be valid, and they may be updated later. References are listed alphabetically by the first author.
New references are added at approximately monthly intervals by merging with the existing references. The most recent references of all will be found in the web page - "this month's references".
- Abe, A., Hinkovska-Galcheva, V., Verma, R. and Shayman, J.A. Isomerization of bis(monoacylglycero)phosphate by acyl migration. J. Lipid Res., 66, 100789 (2025); DOI.
- Aboutaleb, A.S. and others. Health benefits of phytosterols in the management of several non-communicable disorders. Chem. Biodiv., in press (2025); DOI.
- Ada, E. and Seyrantepe, V. Therapeutic targeting of neuroinflammation in sphingolipidosis. Mol. Immun., 187, 121-133 (2025); DOI.
- Adamantidi, T., Grabrucker, A.M. and Tsoupras, T. Targeting platelet activating factor signaling for therapeutic benefits in neurodegenerative disorders. Front. Biosci. (Landmark Ed), 30, 38300 (2025); DOI.
- Aghasizadeh, M., Bahrami, A.R. and Matin, M.M. Polyunsaturated fatty acids in kidney diseases: Navigating the fine line between healing and damage. Biochim. Biophys. Acta, Lipids, 1870, 159668 (2025); DOI.
- Almoraie, M., Spencer, J. and Wagstaff, C. Punicic acid: a potential nutraceutical compound in pomegranate seed oil and its cardiovascular benefits. Foods, 14, 2412 (2025); DOI.
- Anand, P.K. From fat to fire: The lipid-inflammasome connection. Immun. Rev., 329, e13403 (2025); DOI.
- Andersson, L. and others. Ceramide synthase 2 promotes cardiac very-long-chain dihydroceramide accumulation and is linked to arrhythmias and heart failure in humans. Int. J. Mol. Sci., 26, 6859 (2025); DOI.
- Andrade, A.C.D.P and others. Deficiency in platelet 12-lipoxygenase exacerbates inflammation and disease severity during SARS-CoV-2 infection. Proc. Natl. Acad. Sci. USA, 122, e2420441122 (2025); DOI.
- Andriambelo, B., Vachon, A., Dansereau, M.A., Laurent, B. and Plourde, M. Providing lysophosphatidylcholine-bound omega-3 fatty acids increased eicosapentaenoic acid, but not docosahexaenoic acid, in the cortex of mice with the apolipoprotein E3 or E4 allele. Prostaglandins Leukotrienes Essential Fatty Acids (PLEFA), 204, 102661 (2025); DOI.
- Antonopoulou, S. Platelet-activating factor-induced inflammation in obesity: a two-sided coin of protection and risk. Cells, 14, 471 (2025); DOI.
- Aranda-Caño, L., Valderrama, R., Begara-Morales, J.C., Chaki, M., Pedrajas, J.R. and Barroso, J.B. Nitro-fatty acid signaling and intracellular biodistribution in plants. Plant Sci., 362, 112829 (2026); DOI.
- Arnold, W.R., Jain, S., Sinha, V. and Das, A. The hunt for the putative epoxyeicosatrienoic acid receptor. ACS Chem. Biol., 20, 762-777 (2025); DOI.
- Arnoldus, T. and others. Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal-like cancers. Nature Genetics, 57, 1659-1671 (2025); DOI.
- Asamizu, S. Recent advances in discovery and biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPP)-derived lipopeptides. Nat. Prod. Rep., 42, 1622-1638 (2025); DOI.
- Asis, A.C., Asaro, A. and D'Angelo, G. Single cell lipid biology. Trends Cell Biol., 35, 651-666 (2025); DOI.
- Atallah, M., Nasrallah, N., Harb, T., Gerstenblith, G. and Leucker, T.M. The biology of lipoprotein(a): From genetics to molecular mechanisms. Eur. J. Clin. Invest., in press (2025); DOI.
- Babic, D. and others. Biosynthesis of very Long-chain fatty acids is required for Arabidopsis auxin-mediated embryonic and post-embryonic development. Plant J., 123, e70396 (2025); DOI.
- Bachtel, N.D. and others. Intestinal mast cell-derived leukotrienes mediate the anaphylactic response to ingested antigens. Science, 389, eadp0246 (2025); DOI.
- Bahari, H., Jazinaki, M.S., Aghakhani, L., Hatami, A., Rahnama, I. and Malekahmadi, M. Oleoylethanolamide supplementation on cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials. Front. Nutr., 12, 1553288 (2025); DOI.
- Bainour, K., Zulkifli, N., Sam, K.K., Navarro, J.C., Castro, L.F.C., Glasby, C.J., Shu-Chien, A.C. and Monroig, O. Freshwater-adapted polychaetes exhibit a complete enzymatic machinery for synthesizing long-chain polyunsaturated fatty acids. Open Biol., 15, 250159 (2025); DOI.
- Baker, Z.N. and others. Triacylglycerol mobilization underpins mitochondrial stress recovery. Nature Cell Biol., 27, 298-308 (2025); DOI.
- Bakker, C.E., Barghouth, Z., Ramlawi, S. and Avis, T.J. Biochemistry and differential mechanistic activity of antimicrobial lipopeptides from plant pathogen antagonists from the genus Bacillus. Can. J. Plant Pathol., 47, 98-110 (2025); DOI.
- Balla, T. Phosphatidylinositol 4-phosphate; A minor lipid with multiple personalities. Biochim. Biophys. Acta, Lipids, 1870, 159615 (2025); DOI.
- Balleux, G., Höfte, M., Arguelles-Arias, A., Deleu, M. and Ongena, M. Bacillus lipopeptides as key players in rhizosphere chemical ecology. Trends Microbiol., 33, 80-95 (2025); DOI.
- Bandi, S., Schlemper-Scheidt, M.D., Sanchez, R.R., Sutour, S., Glauser, G., Ishida, Y. and von Reuss, S.H. Glycosylated N-acyl phosphoethanolamines as bacterial food-dependent signaling molecules in Caenorhabditis nematodes. ACS Bio Med Chem AU, 5, 602-619 (2025); DOI.
- Banerjee, S. and others. The Vps13-like protein BLTP2 regulates phosphatidylethanolamine levels to maintain plasma membrane fluidity and breast cancer aggressiveness. Nat Cell Biol 27, 1125-1135 (2025); DOI.
- Bankaitis, V.A., Khan, D., Chen, X.R., Wang, Y.X. and Igumenova, T.I. A brief history of phosphatidylinositol transfer proteins: from the backwaters of cell biology to prime time in lipid signaling. Biochim. Biophys. Acta, Lipids, 1870, 159625 (2025); DOI.
- Barneda, D. and others. Phosphoinositide acyl chain diversity: comparative analysis across species and mouse tissues. Biochim. Biophys. Acta, Lipids, 1870, 159640 (2025); DOI.
- Barnhart, S. and others. Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids. J. Lipid Res., 66, 100730 (2025); DOI.
- Barrantes, F.J. The pleomorphic cholesterol sensing motifs of transmembrane proteins. Chem. Phys. Lipids, 266, 105460 (2025); DOI.
- Bates, P.D. and Shockey, J. Towards rational control of seed oil composition: dissecting cellular organization and flux control of lipid metabolism. Plant Physiol., 197, kiae658 (2025); DOI.
- Bayona-Hernandez, A., Miladinovic, A., Antiga, L., Hozak, P., Sztacho, M. and Castano, E. Lipid-lncRNA crossroads: an overview of interactions between lipids and lncRNA. Cells, 14, 1193 (2025); DOI.
- Bergia, T. and Rippa, S. Sphingolipids in fungi: Biosynthesis and key roles in biological processes. Fungal Biol. Rev., 52, 100430 (2025); DOI.
- Berndsen, Z.T. and Cassidy, C.K. The structure of apolipoprotein B100 from human low-density lipoprotein. Nature, 638, 836-843 (2025); DOI.
- Bertolini, M.S. and others. Generation of inositol polyphosphates through a phospholipase C-independent pathway involving carbohydrate and sphingolipid metabolism in Trypanosoma cruzi. mBio, 16, e0331824 (2025); DOI.
- Biernacki, M. and Skrzydlewska, E. Metabolic pathways of eicosanoids-derivatives of arachidonic acid and their significance in skin. Cell. Mol. Biol. Letters, 30, 7 (2025); DOI.
- Binish, F. and Xiao, J.H. Deciphering the role of sphingosine 1-phosphate in central nervous system myelination and repair. J. Neurochem., 169, e16228 (2025); DOI.
- Blades, F., Yazici, A.T., Cater, R.J. and Mancia, F. MFSD2A in focus: the molecular mechanism of omega-3 fatty acid transport. Physiology, 40, 470-483 (2025); DOI.
- Bodin, S., Elhabashy, H., Macdonald, E., Winter, D. and Gauthier-Rouvière, C. Flotillins in membrane trafficking and physiopathology. Biol. Cell, 117, e2400134 (2025); DOI.
- Böhlig, K., Iglesias-Artola, J.M., Asaro, A., Lennartz, H.M., Link, A.C., Drobot, B. and Nadler, A. Bifunctional probes reveal the rules of intracellular ether lipid transport. Angew. Chem.-Int. Ed., 64, e202513360 (2025); DOI.
- Bohn, T. and others. Vitamin A5: evidence, definitions, gaps, and future directions. Nutrients, 17, 2317 (2025); DOI.
- Borén, J., Packard, C.J. and Binder, C.J. Apolipoprotein B-containing lipoproteins in atherogenesis. Nature Rev. Cardiol., 22, 399-413 (2025); DOI.
- Borrelli, C. and others. Polymyxin B lethality requires energy-dependent outer membrane disruption. Nature Microbiology, 10, 2919-2933 (2025); DOI.
- Bortoletto, R., Comacchio, C., Garzitto, M., Piscitelli, F., Balestrieri, M. and Colizzi, M. Palmitoylethanolamide supplementation for human health: A state-of-the-art systematic review of Randomized Controlled Trials in patient populations. Brain Behav. Immun.-Health, 43, 100927 (2025); DOI.
- Borza, R., Matas-Rico, E.,Perrakis, A. and Moolenaar, W.H. Unlocking the signaling potential of GPI-anchored proteins through lipolytic cleavage. Trends Cell Biol., 10.1016/j.tcb.2024.12.010 (2025); DOI.
- Bradshaw, P.C., Aldridge, J.L., Jamerson, L.E., McNeal, C., Pearson, A.C. and Frasier, C.R. The role of cardiolipin in brain bioenergetics, neuroinflammation, and neurodegeneration. Mol. Neurobiol., 62, 7022-7040 (2025); DOI.
- Brahma, S., Chatterjee, S. and Dey, A. Role of eicosanoids in insect immunity: new insights and recent advances. Insect Sci., 32, 753-766 (2025); DOI.
- Brett, C. and Gout, I. The two faces of coenzyme A in cellular biology. Free Rad. Biol. Med., 233, 162-173 (2025); DOI.
- Brunham, L.R. The role of high-density lipoproteins in sepsis. J. Lipid Res., 66, 100728 (2025); DOI.
- Burns, B.C., Belani, J.D., Wittorf, H.N., Brailoiu, E. and Brailoiu, G.C. Choline - an essential nutrient with health benefits and a signaling molecule. Int. J. Mol. Sci., 26, 7159 (2025); DOI.
- Cahoon, E.B., Kim, P., Xie, T., Solis, A.G., Han, G.S., Gong, X. and Dunn, T.M. Sphingolipid homeostasis: How do cells know when enough is enough? Implications for plant pathogen responses. Plant Physiol., 197, kiae460 (2025); DOI.
- Cai, J.L.Y. and others. Reprogramming of fatty acid metabolism via PPARα-orchestrated FADS2 in keratinocytes modulates skin inflammation in psoriasis. Adv. Sci., e17049 (2025); DOI.
- Cai, W.L., Yu, S.Y. and Hu, Y.H. Synergistic mechanisms of DGAT and PDAT in shaping triacylglycerol diversity: evolutionary insights and metabolic engineering strategies. Front. Plant Sci., 16, 1598815 (2025); DOI.
- Cai, Y. and Horn, P.J. Packaging "vegetable oils": Insights into plant lipid droplet proteins. Plant Physiol., 197, kiae533 (2025); DOI.
- Capdevila, J.H., Falck, J.R. and Adebesin, A.M. Epoxyeicosatrienoic acids (EETs): A novel class of second messengers of hormonal functional responses. Prostaglandins Other Lipid Mediators, 177, 106967 (2025); DOI.
- Caputo, M., Gubar, O., Tóth, P., Vitale, N., Gasman, S. and Ory, S. Lipid asymmetry and membrane trafficking: Transbilayer distribution of structural phospholipids as regulators of exocytosis and endocytosis. J. Biol. Chem., 301, 110441 (2025); DOI.
- Carman, G.M., Stukey, G.J., Jog, R. and Han, G.S. Insights into phosphatidic acid phosphatase and its potential role as a therapeutic target. Adv. Biol. Reg., 95, 101074 (2025); DOI.
- Carney, O.S. and others. A review of disorders of cardiolipin metabolism: Pathophysiology, clinical presentation and future directions. Mol. Gen. Metab., 145, 109184 (2025); DOI.
- Carre, R., Vigne, S. and Pot, C. 25-hydroxycholesterol in inflammation. Curr. Opinion Endocr. Metab. Res., 40, 100582 (2025); DOI.
- Caruso, E.A., De Nunzio, V., Tutino, V. and Notarnicola, M. The endocannabinoid system: implications in gastrointestinal physiology and pathology. Int. J. Mol. Sci., 26, 1306 (2025); DOI.
- Chagas, B.C.A., Jia, H.T., Brixius, B. and Brixius-Anderko, S. The curious family of cytochrome P450 4F fatty acid ?-hydroxylases: recent developments in their function and relevance for human health. Open Biol., 15, 250115 (2025); DOI.
- Chakraborty, A., Punnamraju, P., Sajeevan, T., Kaur, A., Kolthur-Seetharam, U. and Kamat, S.S. Identification of ABHD6 as a lysophosphatidylserine lipase in the mammalian liver and kidneys, J. Biol. Chem., 301, 108157 (2025); DOI.
- Chakraborty, S., Kumar, A.S. and Banerjee, S. Lipids: driving forces in the underlying biology of carcinogenesis. ACS Pharm. Transl. Sci., 8, 1891-1918 (2025); DOI.
- Chang, F., Rowart, P., Salvatore, S.R., Rom, O., Mascal, M. and Schopfer, F.J. The emerging significance of furan fatty acids in food, nutrition, and potential therapeutic use. Food Chem., 479, 143759 (2025); DOI.
- Che, X.H., Zhao, Y., Xu, Z.T., Hu, Y., Ren, A.X., Wu, C.F. and Yang, J.Y. Unlocking the potential of L-α-glycerylphosphorylcholine: from metabolic pathways to therapeutic applications. Nutr. Rev., 83, 1594-1620 (2025); DOI.
- Chen, C.H. and others. Evolving concepts of low-density lipoprotein: From structure to function. Eur. J. Clin. Invest., 55, e70019 (2025); DOI.
- Chen, L., Elizalde, M. and Alvarez-Sola, G. The role of sulfatides in liver health and disease. Front. Biosci.-Landmark, 30, 25077 (2025); DOI.
- Chen, M. and others. Antioxidant-independent activities of alpha-tocopherol. J. Biol. Chem., 301, 108327 (2025); DOI.
- Chen, M., Tan, J.X., Sun, Y., Thapa, N., Cryns, V.L. and Anderson, R.A. Agonist- and stress-driven compartmentalized phosphoinositide signaling in cells. Biochim. Biophys. Acta, Lipids, 1870, 159662 (2025); DOI.
- Chen, M.L. and others. Recent advances in antimicrobial lipopeptide fengycin secreted by Bacillus: Structure, biosynthesis, antifungal mechanisms, and potential application in food preservation. Food Chem., 489, 144937 (2025); DOI.
- Chen, R., Tang, X.H., Wang, Y., Wang, B I. and Mao, F. Protein palmitoylation: an emerging regulator of inflammatory signaling and diseases. Front. Immun., 16, 1652741 (2025); DOI.
- Chen, R.N., Wang, P.R., Liu, J.N., Yang, X., Gong, X.Y., Zhou, H.L., Han, N. and Yang, Z. Suberin in plants: biosynthesis, regulation, and its role in salt stress resistance. Front. Plant Sci., 16, 1624136 (2025); DOI.
- Chen, S.Y., Chen, S.M., Yu, X., Wan, C.J., Wang, Y., Peng, L.X. and Li, Q. Sources of lipopeptides and their applications in food and human health: a review. Foods, 14, 207 (2025); DOI.
- Chen, X. and others. A comprehensive review of beneficial effects of phytosterols on glycolipid metabolism and related mechanisms. J. Agric. Food Chem., 73, 3826-3841 (2025); DOI.
- Chen, X. and others. Arachidonoyl-carnitine and arachidonoyl-coenzyme A are suitable substrates for mammalian ALOX isoforms. J. Lipid Res., 66, 100861 (2025); DOI.
- Chen, Y.F., Yang, H., Zheng, F.F., Wu, R.J., Zhang, C.L., Naafs, B.D.A., Pancost, R.D. and Zeng, Z.R. Temperature-dependent modulation of the methylation degree of (tetra) ester-linked membrane-spanning lipids in an Acidobacterium. Geochim. Cosmochim. Acta, 401, 190-203 (2025); DOI.
- Chen, Y.X., Liu, J.R., He, Y.R., Lue, Y. and Yu, W.H. The role of fatty acid binding protein 7 in neurological diseases. Mol. Neurobiol., 62, 14801-14810 (2025); DOI.
- Cheng, R.W., Yang, S.Q., Wang, D.L., Qin, F.C., Wang, S.K. and Meng, S. Advances in the biosynthesis of plant terpenoids: models, mechanisms, and applications. Plants-Basel, 14, 1428 (2025); DOI.
- Cheng, Z.L. and Montgomery, M.K. Physiological roles of phosphoinositides and inositol phosphates: Implications for metabolic dysfunction-associated steatotic liver disease. Clin. Sci., 139, 1073-1122 (2025); DOI.
- Ciesielski, V. and others. Dietary pentadecanoic acid supplementation at weaning in essential fatty acid-deficient rats shed light on the new family of odd-chain n-8 PUFAs. J. Nutr. Biochem., 137, 109814 (2025); DOI.
- Chitkara, S. and Atilla-Gokcumen, G.E. Decoding ceramide function: how localization shapes cellular fate and how to study it. Trends Biochem. Sci., 50, 356-367 (2025); DOI.
- Cho, H.S. and others. Structure of gut microbial glycolipid modulates host inflammatory response. Cell, 188, 1-18 (2025); DOI.
- Choi, J.H. and Kagan, J.C. Oxidized phospholipid damage signals as modulators of immunity. Open Biol., 15, 240391 (2025); DOI.
- Choudhary, P., Kumari, S., Bagri, K. and Deshmukh, R. Ceramide: a central regulator in Alzheimer's disease pathogenesis. Inflammopharm., 33, 1775-1783 (2025); DOI.
- Chytla, A., Rattay, S., Akgül, B. and Sztacho, M. Plasma membrane and nuclear phosphatidylinositol 4,5-bisphosphate signalling in cancer. Lipids Health Dis., 24, 39 (2025); DOI.
- Coleman, R.A. Lipid metabolism on and off the beaten path. J. Biol. Chem., 301, 110697 (2025); DOI.
- Conte, C. and others. Sphingomyelin regulates the transcriptional machinery in nuclear lipid microdomains. Commun. Biol., 8, 1303 (2025); DOI.
- Corvera, S. and others. Advances in adipose tissue biology. Endocrine Rev., in press (2025); DOI.
- Costa, D.O. and others. Circulating membrane amino-phospholipids contribute to thrombotic risk in rheumatoid arthritis. J. Lipid Res. 66, 100842 (2025); DOI.
- Cui, D.X., Yu, X.Q., Guan, Q.Y., Shen, Y., Liao, J.J., Liu, Y. and Su, Z.G. Cholesterol metabolism: molecular mechanisms, biological functions, diseases, and therapeutic targets. Mol. Biomed., 6, 72 (2025); DOI.
- Dakhili, S.A.T., Yang, K.Y., Stenlund, M.J. and Ussher, J.R. The multifaceted roles of ketones in physiology. Exp. Physiol., in press (2025); DOI.
- Das, A.S., Das, A.S., Chen, Z.S., Peisker, H., Gutbrod, K., Hölzl, G. and Dörmann, P. Multifunctional acyltransferases involved in the synthesis of triacylglycerol, fatty acid phytyl esters and plastoquinol esters in cyanobacteria. Planta, 261, 123 (2025); DOI.
- Davidson, J.W. and others. Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV. Cell Metab., 37, 1413-1425.e6 (2025); DOI.
- Davies, E.M., Jones, E.I., Ooms, L.M., Gurung, R., McGrath, M.J. and Mitchell, C.A. Phosphoinositide phosphatases: Modifiers of phosphoinositide signaling in health and disease. Biochim. Biophys. Acta, Lipids, 1870, 159652 (2025); DOI.
- De Matteis, M.A., Fico, M. and Venditti, R. Regulation and function of PI4P at the Golgi complex. Biochim. Biophys. Acta, Lipids, 1870, 159626 (2025); DOI.
- de Mendoza, D. Membranes, where lipids and protein meet. Chem. Phys. Lipids, 268, 105486 (2025); DOI.
- de Sa, A., Li, G.Y., Byrne, C., Lowe, M. The inositol 5-phosphatases OCRL and INPP5B: Cellular functions and roles in disease. Biochim. Biophys. Acta, Lipids, 1870, 159660 (2025); DOI.
- Debédat, J., Pastor, L., Knotts, T.A., Pitman, J.G., Griffett, K. and Adams, S.H. Cyclopropane xenolipids resemble monounsaturated fatty acids and modulate peroxisome proliferator-activated receptors. J. Lipid Res., 66 10089 (2025); DOI.
- Demmig-Adams, B., Hodges, A.K., Polutchko, S.K. and Adams, W.W. Zeaxanthin and other carotenoids: roles in abiotic stress defense with implications for biotic defense. Plants-Basel, 14, 2703 (2025); DOI.
- Deng, C.Y., Garcia-Molina, A., Gómez-Cadenas, A., Vives-Peris, V., Alcázar, R., Ferrer, A. and Altabella, T. Glycosylated sterols enhance cold tolerance in tomato via membrane stabilization and jasmonate signaling. Plant Physiol., 199, kiaf420 (2025); DOI.
- Deng, Q.S. and others. A polyene macrolide targeting phospholipids in the fungal cell membrane. Nature, 640, 743-751 (2025); DOI.
- Deng, Y.Q., Vale, G., Liang, Y.G., Cui, S.J., Xu, S.M., McDonald, J.G. and Ye, J. Protection against ferroptosis through maintaining homeostasis of docosahexaenoate-containing phospholipids, Mol. Cell, 85, 3474-3485 (2025); DOI.
- Di Stefano, V., Steardo, L. Jr., D'Angelo, M., Monaco, F. and Steardo, L. Palmitoylethanolamide: a multifunctional molecule for neuroprotection, chronic pain, and immune modulation. Biomedicines, 13, 1271 (2025); DOI.
- Ding, M. and others. Acid sphingomyelinase recruits palmitoylated CD36 to membrane rafts and enhances lipid uptake. J. Biol. Chem., 301, 110213 (2025); DOI.
- Ding, N., Dong, H.S. and Ongena, M. Bacterial cyclic lipopeptides as triggers of plant immunity and systemic resistance against pathogens. Plants-Basel, 14, 2644 (2025); DOI.
- Dion, D., Noll, C., Fortin, M., Haroune, L., Saibi, S., Sarret, P. and Carpentier, A.C. Plasma endocannabinoids are independently associated with the metabolic function of white adipose tissue. J. Clin. Endocrin. Metab., 110, e1821-e1832 (2025); DOI.
- Domingues, N., Pires, J., Milosevic, I. and Raimundo, N. Role of lipids in interorganelle communication. Trends Cell Biol., 35, 46-58 (2025); DOI.
- Dong, H.J., Zou, Q. and Cronan, J.E. Defining the Enterococcus faecalis fatty acid kinase system of exogeneous fatty acid utilization. Mol. Microbiol., 124, 400-412 (2025); DOI.
- Dong, L., Cao, Z., Han, W.D. and Wu, Z.Q. Synthesis, function, and therapeutic potential of glycosphingolipids. Front. Immun., 16, 1673713 (2025); DOI.
- Du, M., Gong, M., Wu, G., Jin, J., Wang, X. and Jin, Q. Conjugated linolenic acid (CLnA) vs conjugated linoleic acid (CLA): a comprehensive review of potential advantages in molecular characteristics, health benefits, and production techniques. J. Agric. Food Chem., 72, 5503-5525 (2024); DOI.
- Dubot, P., Sabourdy, F. and Levade, T. Human genetic defects of sphingolipid synthesis. J. Inher. Metab. Dis., 48, e12745 (2025); DOI.
- Dunajová, L., Townley, A., Rochette, S., McLean, D., Webster, J.R.M. and Wheatley, S.P Survivin can alter mitochondrial architecture by regulating phosphatidylethanolamine synthesis. J. Cell Sci., 138, jcs263689 (2025); DOI.
- Dupuy, M., Bondonno, N.P., Pokharel, P., Linneberg, A., Levinger, I., Schultz, C., Hodgson, J.M. and Sim, M. Vitamin K: metabolism, genetic influences, and chronic disease outcomes. Food Sci. Nutr., 13, e70431 (2025); DOI.
- Durand, E., Laguerre, M., Bourlieu-Lacanal, C., Lecomte, J. and Villeneuve, P. Navigating the complexity of lipid oxidation and antioxidation: A review of evaluation methods and emerging approaches. Prog. Lipid Res., 97, 101317 (2025); DOI.
- Edin, M.L., Graves, J.P. and Zeldin, D.C. Putative receptors and signaling pathways responsible for the biological actions of epoxyeicosatrienoic acids. J. Biol. Chem., 301, 110737 (2025); DOI.
- Eftekhari, A., Sabir, U. and Kasumov, T. The role of lysine acetylation in metabolic sensing and proteostasis. Pharmacol. Therapeut., 274, 108908 (2025); DOI.
- El-Gazzar, N., Said, L., Al-Otibi, F.O., Abdelgawwad, M.R. and Rabie, G. Antimicrobial and cytotoxic activities of natural (Z)-13-docosenamide derived from Penicillium chrysogenum. Front. Cell. Infect. Microbiol., 15, 1529104 (2025); DOI.
- Ershov, P.V., Yablokov, E.O., Mezentsev, Y. and Ivanov, A.S. Human prostacyclin and thromboxane synthases: Molecular interactions, regulation, and pharmacology. Biochimie, 234, 76-88 (2025); DOI.
- Es-Sai, B., Wahnou, H., Benayad, S., Rabbaa, S., Laaziouez, Y., El Kebbaj, R., Limami, Y. and Duval, R.E. Gamma-tocopherol: a comprehensive review of its antioxidant, anti-inflammatory, and anticancer properties. Molecules, 30, 653 (2025); DOI.
- Fabbian, S., Masciovecchio, B., Schievano, E. and Giachin, G. Hidden β-γ dehydrogenation products in long-chain fatty acid oxidation unveiled by NMR: implications on lipid metabolism. ACS Bio. Med. Chem. Au., 5, 262-267 (2025); DOI.
- Fadaei, R. and others. N-aldehyde-modified phosphatidylethanolamines generated by lipid peroxidation are robust substrates of N-acyl phosphatidylethanolamine phospholipase D. J. Lipid Res., 66, 100831 (2025); DOI.
- Fan, M.J., Yang, Z.Y., Jin, L.H. and Huang, W.D. Differential roles of individual bile acid in physiology and disease. Pharmacol. Res., 218, 107845 (2025); DOI.
- Farese, R.V. and Walther, T.C. Essential biology of lipid droplets. Annu. Rev. Biochem., 94, 447-477 (2025); DOI.
- Feng, W.J., Yang, K.X., Ju, M.W., Wang, T. and Xiao, R. Epigenetic regulation of cholesterol and oxysterol homeostasis. Nutr. Rev., 83, 2389-2406 (2025); DOI.
- Fenton, N.M., Sharpe, L.J. and Brown, A.J. A revised oxysterol hypothesis highlighting the special roles played by 24(S),25-epoxycholesterol. Curr. Opinion Endocr. Metab. Res., 39, 100578 (2025); DOI.
- Fernàndez-Bernal, A., Mota, N., Pamplona, R., Area-Gómez, E. and Portero-Otin, M. Mission cholesterol: Uncovering its hidden role in ALS neurodegeneration. Biochim. Biophys. Acta, Mol. Basis. Dis., 1871, 168021 (2025); DOI.
- Ferrari, A. and Tontonoz, P. Nonvesicular cholesterol transport in physiology. J. Clin. Invest., 135, e188127 (2025); DOI.
- Ferrero, E., Vaz, F.M., Cheillan, D., Brusco, A. and Marelli, C. The ELOVL proteins: Very and ultra long-chain fatty acids at the crossroads between metabolic and neurodegenerative disorders. Mol. Gen. Metab., 144, 109050 (2025); DOI.
- Fu, J.W., Heiden, K.D., Bailey, L.S., Basso, K.B. and Rathinasabapathi, B. Arabidopsis phytyl ester synthases PES1 and PES2 moonlighted as xanthophyll acyltransferases in plants. Planta, 262, 51 (2025); DOI.
- Fukuishi, N., Takahama, K., Kurosaki, H., Ono, S. and Asai, H. The role of endogenous specialized proresolving mediators in mast cells and their involvement in inflammation and resolution. Int. J. Mol. Sci., 26, 1491 (2025); DOI.
- Furukawa, K., Ohmi, Y., Hamamura, K., Ohkawa, Y., Hashimoto, N., Tajima, O., Kaneko, K. and Furukawa, K. GD2 is a crucial ganglioside in the signal modulation and application as a target of cancer therapeutics. Cancer Sci., 116, 862-870 (2025); DOI.
- Gajendran, T.Y., Ganamurali, N. and Sabarathinam, S. 7-Ketocholesterol: A pathogenic oxysterol in atherosclerosis and lysosomal storage disorders-Molecular insights and clinical implications. J. Steroid Biochem. Mol. Biol., 252, 106797 (2025); DOI.
- Gallego, R.P., von Meijenfeldt, F.A.B., Bale, N.J., Damsté, J.S.S. and Villanueva, L. Emergence and evolution of heterocyte glycolipid biosynthesis enabled specialized nitrogen fixation in cyanobacteria. Proc. Natl. Acad. Sci. USA, 122, e2413972122 (2025); DOI.
- Gamerdinger, M. and others. Mechanism of cotranslational protein N-myristoylation in human cells. Mol. Cell, 85, 2749-2758 (2025); DOI.
- Ganley, J.G. and Seyedsayamdost, M.R. Iron limitation triggers roseoceramide biosynthesis and membrane remodeling in marine roseobacter. Proc. Natl. Acad. Sci. USA, 122, 2414434122 (2025); DOI.
- Gao, Y.H. and others. Saturated ceramide is required for seed germination in soybean. Seed Biol., 4, e006 (2025); DOI.
- Geng, J. and others. Current status of cyclopropane fatty acids on bacterial cell membranes characteristics and physiological functions. Microbial Path., 200, 107295 (2025); DOI.
- Ghorashi, A.C. and others. Fucosylation of glycoproteins and glycolipids: opposing roles in cholera intoxication. Nature Chem. Biol., 21, 555-566 (2025); DOI.
- Gishini, M.F.S., Kachroo, P. and Hildebrand, D. Fatty acid desaturase 3-mediated ?-linolenic acid biosynthesis in plants. Plant Physiol., 197, kiaf012 (2025); DOI.
- Goerger, K., Stanger, L., Rickenberg, A., Nguyen, A., Lee, T., Holman, T.R. and Holinstat, M. The EPA oxylipin, 12-HEPE, directly regulates human platelet activity. J. Lipid Res., 66, 100807 (2025); DOI.
- Goetzman, E.S. and others. Dietary dicarboxylic acids provide a nonstorable alternative fat source that protects mice against obesity. J. Clin. Invest., 134, e174186 (2024); DOI.
- Gomez-Larrauri, A., Benito-Vicente, A., Larrea-Sebal, A., Martin, C. and Gomez-Muñoz, A. Role of ceramide kinase/C1P in the regulation of cell growth and survival. Int. J. Mol. Sci., 26, 8374 (2025); DOI.
- Gomez-Larrauri, A., Larrea-Sebal, A., Martín, C. and Gomez-Muñoz, A. The critical roles of bioactive sphingolipids in inflammation. J. Biol. Chem., 301, 110475 (2025); DOI.
- Grossi, V. and others. Halophilic archaea produce wax esters and use an alternative fatty acyl-coenzyme A reductase for precursor synthesis. ISME J., 19, wraf035 (2025); DOI.
- Gründling, A., Brogan, A.P., James, M.J., Ramirez-Guadiana, F.H., Roney, I.J., Bernhardt, T.G. and Rudner, D.Z. PgpP is a broadly conserved phosphatase required for phosphatidylglycerol lipid synthesis. Proc. Natl. Acad. Sci. USA, 122, e2418775122 (2025); DOI.
- Grytten, E. and others. Inflammatory markers after supplementation with marine n-3 or plant n-6 PUFAs: A randomized double-blind crossover study. J. Lipid Res., 66, 100770 (2025); DOI.
- Guerfali, M. Rhodotorula-derived polyol esters of fatty acids (PEFA): Insights into a promising class of high-value glycolipids. Process Safe. Environ.Protect., 195, 106815 (2025); DOI.
- Gupta, V.K., Gupta, K., Sonker, P., Mishra, M. and Kumar, A. Role of lysophosphatidic acid in the regulation of immune cells and hematological malignancies. Prostaglandins Other Lipid Mediators, 180, 107028 (2025); DOI.
- Guy, A.T. and others. Lysophospholipid stereoisomers exert distinct GPR55-mediated functions via different G? subunits. J. Biol. Chem., 301, 110324 (2025); DOI.
- Guzman, G. and others. Characterization of Caenorhabditis elegans sphingomyelin synthases through heterologous expression. J. Biol. Chem., 301, 110300 (2025); DOI.
- Hajeer, W., Blanco, A., Miller, A.P. and Amengual, J. Recent advances in carotenoid absorption, distribution, and elimination. Biochim. Biophys. Acta, Lipids, 1870, 159619 (2025); DOI.
- Hannun, Y.A., Merrill, A.H. and Luberto, C. The bioactive sphingolipid playbook. A primer for the uninitiated as well as sphingolipidologists. J. Lipid Res., 66, 100813 (2025); DOI.
- Haukaas, H.S. and Stenmark, H. Phosphoinositides as regulators of membrane contact sites. Biochim. Biophys. Acta, Lipids, 1870, 159673 (2025); DOI.
- Hayashi, D., Batsika, C.S., Bourboula, A., Shinohara, M., Kanamaru, K., Kokotos, G. and Dennis, E.A. Specificity mechanism of Group VIA calcium-independent phospholipase A2 toward truncated-oxidized phospholipids and its application for specific inhibitor design. Biochim. Biophys. Acta, Lipids, 1870, 159655 (2025); DOI.
- He, Z.Y., Zhang, L.L., Gong, S.Y., Yang, X.D. and Xu, G.X. Cholesterol metabolism and cancer: Molecular mechanisms, immune regulation and an epidemiological perspective (Review). Int. J. Mol. Med., 56, 226 (2025); DOI.
- Hedger, G. and Yen, H.Y. The influence of phosphoinositide lipids in the molecular biology of membrane proteins: recent insights from simulations. Int. J. Mol. Biol., 437, 168937 (2025); DOI.
- Heilmann, M. and Heilmann, I. Getting attached to membranes - How plant signaling networks employ PtdIns(4,5)P2. Plant Physiol., 197, kiae393 (2025); DOI.
- Hein, V. and others. The GD3 ganglioside promotes cell growth, plasticity and chemotherapy resistance of human glioblastoma cancer stem cells. Cancer Cell Int., 25, 246 (2025); DOI.
- Heise, N., Koeller, C.M., Sharif, M. and Bangs, J.D. Stage-specific function of sphingolipid synthases in African trypanosomes. mBio, 16, e03501-24 (2025); DOI.
- Hernández, C.B., Tsiotsia, A., Pipitò, L., Chamberlain, L.H., Greaves, J. and Triola, G. Different chains for different gains: How acyl chain diversity shapes S-acylated protein function. Prog. Lipid Res., 100, 101354 (2025); DOI.
- Hidrobo, M.S. and others. Cold-induced phosphatidylethanolamine synthesis in liver and brown adipose tissue of mice. Biochim. Biophys. Acta, Lipids, 1870, 159562 (2025); DOI.
- Hifdi, N., Vaucourt, M., Hnia, K., Panasyuk, G. and Vandromme, M. Phosphoinositide signaling in the nucleus: Impacts on chromatin and transcription regulation. Biol. Cell, 117, e2400096 (2025); DOI.
- Holdaway, C.M. and others. Alterations in phosphatidylethanolamine metabolism impacts hepatocellular lipid storage, energy homeostasis, and proliferation. Biochim. Biophys. Acta, Lipids, 1870, 159608 (2025); DOI.
- Honda, A., Ueda, H., Miyazaki, T. and Ikegami, T. Oxysterol-related disorders. Curr. Opinion Endocr. Metab. Res., 40, 100583 (2025); DOI.
- Hornemann, T. Sphingoid base diversity. Atherosclerosis, 401, 119091 (2025); DOI.
- Hou, X.T. and others. Phosphoinositide signalling in cell motility and adhesion. Nature Cell Biol., 27, 736-748 (2025); DOI.
- Hou, X.T., Chen, Y., Carrillo, N.D., Cryns, V.L., Anderson, R.A., Sun, J.C., Wang, S.L. and Chen, M. Phosphoinositide signaling at the cytoskeleton in the regulation of cell dynamics. Cell Death Disease, 16, 296 (2025); DOI.
- Hou, Y.N., Liu, S.J., Chen, F., Wang, S., Song, S.Y., Yang, W.Q. and Li, L.M. 20-HETE: Its potential role in physiological and pathophysiological processes. Biochem. Pharm., 242, 117238 (2025); DOI.
- Hoyt, L.R. and others. Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis in mice. Science, 389, eadp0240 (2025); DOI.
- Hu, W.B., Huo, X.Y., Ma, T.F., Li, Z.G., Yang, T.Y., Yang, H.L. and Feng, S.S. Insights into the role of cyclopropane fatty acid synthase (CfaS) from extreme acidophile in bacterial defense against environmental acid stress. Extremophiles, 29, 1 (2025); DOI.
- Huang, W.H., Liu, J.H., Zhao, L.X. and He, H.M. Function of ceramides in the skin and its relationship with skin disease. J. Steroid Biochem. Mol. Biol., 254, 106842 (2025); DOI.
- Huang, W.W. and others. Cis-Palmitoleic acid regulates lipid metabolism via diacylglycerol metabolic shunting. Foods, 14, 2504 (2025); DOI.
- Huang, Y.Q., Li, H.Y., Gu, J.L., Li, Z.R., Bao, W.J. and Wang, X.S. Branched-chain fatty acids with different structure exhibit distinct anti-hepatoma activities and characteristics. Chem. Phys. Lipids, 273, 105549 (2025); DOI.
- Huelsmeier, A.J. Glycosphingolipids in neurodegeneration - Molecular mechanisms, cellular roles, and therapeutic perspectives. Neurobiol. Disease, 207, 106851 (2025); DOI.
- Hummels, K.R. The regulation of lipid A biosynthesis. J. Biol. Chem., 301, 110556 (2025); DOI.
- Hutchinson, E.S., Martinez-Carranza, M., Fu, B., Mäler, L. and Stenmark, P. Structure and membrane interactions of Arabidopsis thaliana DGD2, a glycosyltransferase in the chloroplast membrane. J. Biol. Chem., 301, 108431 (2025); DOI.
- Inamori, K.I. and Inokuchi, J.I. When ganglioside pathways go awry: congenital disorders and experimental insights. J. Human Gen., in press (2025); DOI.
- Ioannidis, M., Tjepkema, J., Uitbeijerse, M.R.P. and van den Bogaart, G. Immunomodulatory effects of 4-hydroxynonenal. Redox Biol., 85, 103719 (2025); DOI.
- Iqbal, A., Bao, H.N., Wang, J., Liu, H.J., Liu, J.T., Huang, L.Q. and Li, D.P. Role of jasmonates in plant response to temperature stress. Plant Sci., 355, 112477 (2025); DOI.
- Isot, I., Yangi, D.D., Demirel-Yalciner, T., Surh, Y., Ozer, N.K. and Sozen, E. 17-Oxo-DHA potentiates macrophage efferocytosis via Nrf2/HO-1-mediated biosynthesis of specialized pro-resolving mediators. IUBMB Life, 77, e70057 (2025); DOI.
- Ito, R., Endo, M., Aoki, M., Fujiwara, S. and Sato, N. Evolutionary conservation of acylplastoquinone species from cyanobacteria to eukaryotic photosynthetic organisms of green and red lineages. Front. Plant Sci., 16, 1569038 (2025); DOI.
- Ivashkevich, D., Ponomarenko, A., Manzhulo, I. and Dyuizen, I. Mechanistic insights into N-oleoylethanolamide-mediated hepatoprotection via PPAR-α. Biocell, 49, 607-627 (2025); DOI.
- Jaganjac, M., Markovic, A.S., Deiana, N. and Zarkovic, N. Short overview on the involvement of lipid peroxidation product 4-hydroxynonenal in diverse pathways of cell death. Front. Biosci.-Landmark, 30, 37139 (2025); DOI.
- Jang, Y. Bioactive compounds targeting dihydroceramide and their therapeutic potential in cancer treatment. Cancers, 17, 909 (2025); DOI.
- Jha, A. and Kumar, H. The overlooked complexity of Resolution: Specialized pro-resolving mediators in focus. Eur. J. Pharm., 1002, 177808 (2025); DOI.
- Ji, X., Xu, C.Y., Luo, J.H., Hu, X.H. and Wu, X.M. S-Palmitoylation in bone biology: emerging insights and therapeutic potential. Biochem. Pharm., 242, 117232 (2025); DOI.
- Jiang, H. and others. Multiple roles of palmitic acid in cardiovascular diseases. J. Inflam. Res., 18, 14515-14533 (2025); DOI.
- Jiang, Y.L., Zhang, M. and Sun, M.Y. ACSL4 at the helm of the lipid peroxidation ship: a deep-sea exploration towards ferroptosis. Front. Pharm., 16, 1594419 (2025); DOI.
- Jing, N. and others. The gut microbiota mediates epoxy eicosanoid metabolism in the colon. J. Biol. Chem., 301, 110338 (2025); DOI.
- Jitobaom, K. and Auewarakul, P. Inositol metabolism as a broad-spectrum antiviral target. Front. Microbiol., 16, 1620775 (2025); DOI.
- Jwa, N.S. and Hwang, B.K. Ferroptosis in plant immunity. Plant Commun., 6, 101299 (2025); DOI.
- Kabeya, N. and others. Methyl-end desaturases determine the capability for de novo biosynthesis of polyunsaturated fatty acids in bivalves. Biochim. Biophys. Acta, Lipids, 1870, 159617 (2025); DOI.
- Kachoueiyan, F. and others. Butyrate: a key mediator of gut-brain communication in Alzheimer's disease. Metab. Brain Dis., 40, 189 (2025); DOI.
- Kalkman, H.O. and Smigielski, L. Ceramides may play a central role in the pathogenesis of Alzheimer's disease: a review of evidence and horizons for discovery. Mol. Neurobiol., 62, 14424-14441 (2025); DOI.
- Kalyesubula, M., Von Bank, H., Davidson, J.W., Burhans, M.S., Becker, M.M., Aljohani, A., Simcox, J. and Ntambi, J.M. Stearoyl-CoA desaturase 1 deficiency drives saturated lipid accumulation and increases liver and plasma acylcarnitines. J. Lipid Res., 66, 100824 (2025); DOI.
- Kanemaru, K. and Nakamura, Y. Phosphatidylinositol-specific phospholipase C across biological kingdoms: domain organization, functions and regulation. J. Biochem., 178, 305-313 (2025); DOI.
- Kang, J.H., Toita, R., Kawano, T., Murata, M. and Kano, A. Phospholipids and their metabolites as diagnostic biomarkers of human diseases. Prog. Lipid Res., 99, 101340 (2025); DOI.
- Kattuman, E.E.S., Teegala, L.R., Darzi, S., Thodeti, C.K. and Paruchuri, S. Leukotrienes: bridging the inflammatory gap in asthma and inflammatory bowel diseases (IBD). Comp. Physiol., 15, e70022 (2025); DOI.
- Kenny, T.C., Scharenberg, S., Abu-Remaileh, M. and Birsoy, K. Cellular and organismal function of choline metabolism. Nature Metab., 7, 35-52 (2025); DOI.
- Kharrat, O. and others. Molecular recognition of fungal methylated glucosylceramides by ETD151 defensin. J. Biol. Chem., 301, 110587 (2025); DOI.
- Kim, D. and others. Mitochondrial NADPH fuels mitochondrial fatty acid synthesis and lipoylation to power oxidative metabolism. Nature Cell Biol., 27, 790-800 (2025); DOI.
- Kim, M. and Zheng, Z. Walking the VLDL tightrope in cardiometabolic diseases. Trends Endocrinol. Metab., 36, 278-291 (2025); DOI.
- Kim, Y.A., Lee, Y. and Kim, M.S. Carnitine shuttle and ferroptosis in cancer. Antioxidants, 14, 972 (2025); DOI.
- Kiriyama, Y., Tokumaru, H., Sadamoto, H. and Nochi, H. Biological actions of bile acids via cell surface receptors. Int. J. Mol. Sci., 26, 5004 (2025); DOI.
- Kitaoka, N. Existence, biosynthesis, metabolism, bioactivities, and biological functions of 12-hydroxyjasmonates. Biosci. Biotechn. Biochem., 89, 1531-1538 (2025); DOI.
- Koley, S. and others. Persistent fatty acid catabolism during plant oil synthesis. Cell Rep., 44, 115492 (2025); DOI.
- Komazin, G., Wigmore, R.M., Ranade, A.M., Rizk, AA., Gardiner, J.H. and Meredith, T.C. Lipoprotein N-terminal modification in Bacillus: a new paradigm for extracellular acetylation and species-dependent Toll-like receptor 2 immunomodulation. mBio, 16, e0099625 (2025); DOI.
- Kosma, D.K., Graça, J. and Molina, I. Update on the structure and regulated biosynthesis of the apoplastic polymers cutin and suberin. Plant Physiol., 197, kiae653 (2025); DOI.
- Kotowska, A.M., Hiramatsu, F., Alexander, M.R., Scurr, D.J., Lightfoot, J.W. and Chauhan, V.M. Surface lipids in nematodes are influenced by development and species-specific adaptations. J. Am. Chem. Soc., 147, 6439-6449 (2025); DOI.
- Koudelka, A. and others. Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling. J. Lipid Res., 66, 100705 (2025); DOI.
- Kumari, A. and others. ANGPTL3/8 is an atypical unfoldase that regulates intravascular lipolysis by catalyzing unfolding of lipoprotein lipase. Proc. Natl. Acad. Sci. USA, 122, e2420721122 (2025); DOI.
- Kumar, A., Partap, M. and Warghat, A.R. Jasmonic acid: a versatile phytohormone regulating growth, physiology, and biochemical responses. J. Plant Growth Reg., 44, 131-154 (2025); DOI.
- Lancaster, G.I. and Murphy, A.J. Do physiological changes in fatty acid composition alter cellular ferroptosis susceptibility and influence cell function? J. Lipid Res., 66, 100765 (2025); DOI.
- Lather, S. and Garg, N. Unraveling the complexity of ferroptosis in plants: Triggers, pathways, antioxidant system and connecting links. Plant Physiol. Biochem., 228, 110221 (2025); DOI.
- Laureano, G., Matos, A.R. and Figueiredo, A. Exploring the potential of lipid elicitors to enhance plant immunity. Prog. Lipid Res., 98, 101332 (2025); DOI.
- Laxalt, A.M., van Hooren, M. and Munnik, T. Plant PI-PLC signaling in stress and development. Plant Physiol., 197, kiae534 (2025); DOI.
- Lee, J. and Roh, J.L. Lipid metabolism in ferroptosis: Unraveling key mechanisms and therapeutic potential in cancer. Biochim. Biophys. Acta, Rev. Cancer, 1880, 189258 (2025); DOI.
- Lee, M., Boyce, J.A. and Barrett, N.A. Cysteinyl leukotrienes in allergic inflammation. Annu. Rev. Pathol., Mechanisms Disease, 20, 115-141 (2025); DOI.
- Lee-Okada, H.C., Xue, C.X. and Yokomizo, T. Recent advances on the physiological and pathophysiological roles of polyunsaturated fatty acids and their biosynthetic pathway. Biochim. Biophys. Acta, Lipids, 1870, 159564 (2025); DOI.
- Lentini, G., Querqui, A., Giuliani, A., Verna, R. and Bizzarri, M. Inositol and PIP2/PIP3 ratio: at the crossroad of the biodynamic interface between cells and their microenvironment. Biomolecules, 15, 451 (2025); DOI.
- Lesur, E. and others. Synthetic mycolates derivatives to decipher protein mycoloylation, a unique post-translational modification in bacteria. J. Biol. Chem., 301, 108243 (2025); DOI.
- Li, D.Y., Chen, H.W., Vale, G., Meinhardt, N.E., Hatton, A., Rong, S.X., McDonald, J.G. and Li, X.C. Molecular insights into human phosphatidylserine synthase 2 and its regulation of SREBP pathways. Proc. Natl. Acad. Sci. USA, 122, e2501177122 (2025); DOI.
- Li, D.Y. and others. Endogenous synthesis of n-3 PUFAs can reduce lipid synthesis in Fad3 transgenic cattle. Biochim. Biophys. Acta, Lipids, 1870, 159672 (2025); DOI.
- Li, J.H., Zhang, J.P., Wang, Y., Yang, Y.J., Su, Y.J., Gu, L.P. and Chang, C.H. L-Alpha-Glycerylphosphorylcholine (L-?-GPC): a comprehensive review of its preparation techniques and versatile biological effects. J. Food Sci., 90, e70338 (2025); DOI.
- Li, L.L., Huang, Y.X., Gui, Y.Q., Xiang, W.Q., Yang, M., Hou, Y. and Peng, M.X. The role of phosphatidylcholine metabolism in tumors. Med. Oncol., 42, 450 (2025); DOI.
- Li, N.J. and Li, G.B. Sphingolipid signaling in kidney diseases. Am. J. Physiol., Renal Physiol., 328, F431-F443 (2025); DOI.
- Li, T., He, H.Y., Zhang, .EJ., Hu, F.J., Wang, Z., Xu, J., Zeng, M.L. and Peng, B.W. The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system. Brain Pathol., in press (2025); DOI.
- Li, Y., Liu, Q., Pan, C.Y. and Lan, X.Y. The free fatty acid receptor 2 (FFA2): Mechanisms of action, biased signaling, and clinical prospects. Pharmacol. Therapeut., 272, 108878 (2025); DOI.
- Li, Y.-K., Zhang, Y.-M., Dai, G.-Y., Chen, Y.-L., Chen, D.-K. and Yao, N. Sphingolipid remodeling in the plasma membrane is essential for osmotic stress tolerance in Arabidopsis. Plant Physiol., 197, kiaf031 (2025); DOI.
- Li, Y.X., Li, Z., Ran, Q. and Wang, P. Sterols in ferroptosis: from molecular mechanisms to therapeutic strategies. Trends Mol. Med., 31, 36-49 (2025); DOI.
- Li, Z.Z., Xiao, H.X., Hu, J.J., Xie, W., Wang, Z.X., Pan, Y.P., Li, X.H. and Yu, X.F. The mechanisms and implications of cardiolipin in the regulation of cell death. Cell Biochem. Function, 43, e70066 (2025); DOI.
- Liepinsh, E. and others. EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines. Biofactors, 51, e70014 (2025); DOI.
- Lin, J.H., Lai, Y.F., Lu, F.J. and Wang, W.M. Targeting ACSLs to modulate ferroptosis and cancer immunity. Trends Endocrinol. Metab., 36, 677-690 (2025); DOI.
- Lin, L., Sun, ML., Wang, K., Gao, J., Ji, X.-J. and Zhao, Q. Biosynthesis of conjugated linoleic acid: current status and future perspectives. Bioresour. Bioprocess., 12, 72 (2025); DOI.
- Lin, W.J and others. LipidFun: a database of lipid functions. Bioinformatics, 41, btaf110 (2025); DOI.
- Liong, A. and Leao, P.N. Fatty acyl-AMP ligases in bacterial natural product biosynthesis. Nat. Prod. Rep., 42, 739-753 (2025); DOI.
- Lis, J., Fichna, J. and Tarasiuk-Zawadzka, A. The role of free fatty acid receptors activation in pancreatic disorders. Mol. Aspects Med., 104, 101386 (2025); DOI.
- Liu, H.C., Wen, S., Xu, C., Kang, X.H. and Kong, E.Y. Mechanisms and functional implications of ZDHHC5 in cellular physiology and disease. J. Lipid Res., 66, 100793 (2025); DOI.
- Liu, H.Z., Gishini, M.F.S., Kurokawa, T., Singh, R.M., Kachroo, A. and Kachroo, P. Role of cuticle, sterols, sphingolipids, and glycerolipids in plant defense. J. Exp. Botany, in press (2025); DOI.
- Liu, T. and Ai, D. Roles of lipoxygenases in cardiovascular diseases. J. Cardiovasc. Transl. Res., 18, 599-610 (2025); DOI.
- Liu, X., Duan, L.Q. and Song, J.M. Phosphorus limitation induces membrane lipid remodeling in aquatic phytoplankton. Marine Environ. Res., 212, 107526 (2025); DOI.
- Liu, X.J. and others. Peroxisomal metabolism of branched fatty acids regulates energy homeostasis. Nature, 646, 1223-1231 (2025); DOI.
- Liu, X.R., Li, M., Hao, Q.Q., Yu, Y.J., Liao, C., Yu, R., Kong, D.L. and Wang, Y. Unraveling cysteinyl leukotrienes and their receptors in inflammation through the brain-gut-lung axis. Virulence, 16, 2502555 (2025); DOI.
- Liu, X.X., Izzat, S., Wang, G.Q., Xiong, Z.Q. and Ai, L.Z. Research progress on biosynthesis and regulation of conjugated linoleic acid in lactic acid bacteria. Biotechn. Appl. Biochem., 72, 1450-1457 (2025); DOI.
- Liu, Y.Q. and others. Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE. Nature Commun., 16, 3974 (2025); DOI.
- Liu, Z.H. and You, C.G. The bile acid profile. Clin. Chim. Acta, 565, 120004 (2025); DOI.
- Los, D.A. and Leusenko, A. 50 years since the concept of homeoviscous adaptation. Biochimie, 231, 98-103 (2025); DOI.
- Löser, T., Bekbulat, F., Behl, C. and Schepers, J. Phosphatidylinositol 3-phosphate metabolism impacts cellular ?-synuclein localization in Saccharomyces cerevisiae. J. Biol. Chem., 301, 110666 (2025); DOI.
- Lu, T.T. and others. ARV1 is a component of the enzyme initiating glycosylphosphatidylinositol biosynthesis. J. Biol. Chem., 301, 110236 (2025); DOI.
- Lundgren, J.G., Flynn, M.G. and List, K. GPI-anchored serine proteases: essential roles in development, homeostasis, and disease. Biol. Chem., 406, 1-28 (2025); DOI.
- Luo, Y.Q., Xue, H.P., Gao, Y., Ji, G. and Wu, T. Sphingosine kinase 2 in cancer: A review of its expression, function, and inhibitor development. Int. J. Biol. Macromol., 306, 141392 (2025); DOI.
- Lysyganicz, P.K., Barbosa, A.D., Khondker, S., Stewart, N.A., Carman, G.M., Stansfeld, P.J., Dymond, M.K. and Siniossoglou, S. Partitioning of fatty acids between membrane and storage lipids controls ER membrane expansion. EMBO J., 44, 781-800 (2025); DOI.
- Ma, X.C. and Clardy, J. Spontaneous generation of an endogenous ROR?t agonist. J. Am. Chem. Soc., 147, 11688-11692 (2025); DOI.
- Ma, Y.L. and others. Glycosylphosphatidylinositol biosynthesis functions as a conserved host defense pathway against coronaviruses via regulation of LY6E. PLOS Pathogens, 21, e1013441 (2025); DOI.
- Machhua, P., Unnithan, V.G., Liu, Y., Jiang, Y.P., Zhang, L.F. and Guo, Z.H. Daptomycin forms a stable complex with phosphatidylglycerol for selective uptake to bacterial membrane. eLife, 13, RP93267 (2025); DOI.
- Macrae, C., Lalovic, D., Bunney, T.D. and Katan, M. Phosphoinositide-specific phospholipase C enzymes: Recent advances in a long journey. Biochim. Biophys. Acta, Lipids, 1870, 159627 (2025); DOI.
- Mahawar, U. and Wattenberg, B. Intricate regulation of sphingolipid biosynthesis: an in-depth look into ORMDL-mediated regulation of serine palmitoyltransferase. Bioessays, 47, e70036 (2025); DOI.
- Manhertz-Patterson, R. and Atilla-Gokcumen, G.E. S-acylation in apoptotic and non-apoptotic cell death: a central regulator of membrane dynamics and protein function. Biochem. Soc. Trans., 53, 487-496 (2025); DOI.
- Mansilla, M.C. and de Mendoza, D. Fatty acid synthesis and utilization in gram-positive bacteria: insights from Bacillus subtilis. Microbiol. Mol. Biol. Rev., 89, e0006923 (2025); DOI.
- Markelova, N. and Chumak, A. Antimicrobial activity of Bacillus cyclic lipopeptides and their role in the host adaptive response to changes in environmental conditions. Int. J. Mol. Sci., 26, 336 (2025); DOI.
- Marques, A.R.A and others. Glucosylated cholesterol accumulates in atherosclerotic lesions and impacts macrophage immune response. J. Lipid Res., 66, 100825 (2025); DOI.
- Marqués-Gálvez, J.E., Weston, D.J. and Veneault-Fourrey, C. To immunity and beyond: the central role of jasmonate signalling in beneficial root-microbe-environment interactions. New Phytol., 247, 2564-2570 (2025); DOI.
- Maryam, A., Khan, R.I., Abbas, M., Hussain, K., Muhammad, S., Sabir, M.A., Ahmed, T. and Khalid, M.F. Beyond the membrane: the pivotal role of lipids in plants abiotic stress adaptation. Plant Growth Reg., in press (2025); DOI.
- Mata-Pérez, C. and others. Nitro-fatty acids modulate germination onset through S-nitrosothiol metabolism. Plant Physiol., 197, kiaf038 (2025); DOI.
- Matthews, B., Steeves, S.A., Akefe, I.O., Ahmed, N.Y., Gormal, R.S., Dehorter, N., Wallis, T.P. and Meunier, F.A Lysine myristoylation mediates long-term potentiation via membrane enrichment of synaptic plasticity effectors. EMBO J., 44, 4196-4221 (2025); DOI.
- Maurício, T. and others. Phosphatidylethanolamine species with n-3 and n-6 fatty acids modulate macrophage lipidome and attenuate responses to LPS stimulation. Biochim. Biophys. Acta, Lipids, 1870, 159614 (2025); DOI.
- Mauger, M. and others. Towards bacterial resistance via the membrane strategy: enzymatic, biophysical and biomimetic studies of the lipid cis-trans isomerase of Pseudomonas aeruginosa. Chembiochem, 26, e202400844 (2025); DOI.
- May, K.L. and Grabowicz, M. Outer membrane lipoproteins: late to the party, but the center of attention. J. Bact., 207, e00442-24 (2025); DOI.
- MckeOubonna, S., Jung, K.I., Wolf, J.J., Seo, Y.J. and Hahm, B. Multiple sphingolipid-metabolizing enzymes modulate influenza virus replication. Virology, 603, 110367 (2025); DOI.
- Mclaughlin, J.E. and Tumer, N.E. Roles of non-specific lipid transfer proteins in plant defense: structural and functional perspectives. Front. Fungal Biol., 6, 1640465 (2025); DOI.
- Merheb, C., Gerbal-Chaloin, S., Casas, F., Diab-Assaf, M., Daujat-Chavanieu, M. and Feillet-Coudray, C. Omega-3 fatty acids, furan fatty acids, and hydroxy fatty acid esters: dietary bioactive lipids with potential benefits for MAFLD and liver health. Nutrients, 17, 1031 (2025); DOI.
- Merrill, A.H. Don't be surprised when these surprise you: some infrequently studied sphingoid bases, metabolites, and factors that should be kept in mind during sphingolipidomic studies. Int. J. Mol. Sci., 26, 650 (2025); DOI.
- Michell, R.H. What was the scientific context in which I wrote my 1975 Inositol phospholipids and cell surface receptor function review? Biochim. Biophys. Acta, Lipids, 1870, 159601 (2025); DOI.
- Miranda-Molina, A., Alvarez, L., Antunez-Mojica, M. and Velasco-Bejarano, B. Reviewing glycosyl-inositols: natural occurrence, biological roles, and synthetic techniques. Chembiochem, 26, e202400823 (2025); DOI.
- Mirtaleb, M.S., Bakhshandeh, B., Mohammadipanah, F., Shirazi, S.R.S. and Mobashery, A.R. Bacterial and fungal quorum sensing interactions with human cells., mechanisms and potential therapeutical applications. Microbial Pathogenesis, 207, 107925 (2025); DOI.
- Mishima, E. and others. Recommendations for robust and reproducible research on ferroptosis. Nature Rev. Mol. Cell Biol., 26, 615-630 (2025); DOI.
- Mittendorf, J., Haslam, T.M., Herrfurth, C., Esnay, N., Boutte, Y., Feussner, I. and Lipka, V. Identification of Inositol Phosphorylceramide Synthase 2 (IPCS2) as a new rate-limiting component in Arabidopsis pathogen entry control. Plant J., 122, e70159 (2025); DOI.
- Moffatt, C.B., Plaman, B.A., Rowe, S.J., Caruso, A., Early, S.A., Ruiz, N. and Kahne, D. Inhibiting lipopolysaccharide biogenesis: the more you know the further you go. Annu. Rev. Biochem., 94, 137-160 (2025); DOI.
- Mohammed, T.A. and Zalzala, M.H. Impact of nuclear receptors on the control of bile acid metabolism and synthesis: a comprehensive review. Curr. Pharm. Rep., 11, 25 (2025); DOI.
- Mohanty, I., Allaband, C., Mannochio-Russo, H., El Abiead, Y., Hagey, L.R., Knight , R. and Dorrestein, P.C. The changing metabolic landscape of bile acids - keys to metabolism and immune regulation. Nat. Rev. Gastroenterol. Hepatol., 21, 493-516 (2024); DOI.
- Mondal, S., Pal, B. and Sankaranarayanan, R. Mechanistic understanding of bacterial FAALs and the role of their homologs in eukaryotes. Proteins Struct. Funct. Bioinf., 93, 26-37 (2025); DOI.
- Monyror, J. and others. Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo. Sci. Adv., 11, eady5212 (2025); DOI.
- Monte, M.J., Fabrega, L., Romero, M.R., Temprano, A.G., Kaplowitz, N., Garcia-Ruiz, C., Marin, J.J.G. and Fernandez-Checa, J.C. Bile acids in liver and gastrointestinal cancer. Seminars Cancer Biol., 116, 45-58 (2025); DOI.
- Mostaq, M.S., Kang, L., Patwardhan, G.A., Zhao, Y.F., Shi, R.H. and Liu, Y.Y. Glucosylceramide synthase, a key enzyme in sphingolipid metabolism, regulates expression of genes accounting for cancer drug resistance. Int. J. Mol. Sci., 26, 5112 (2025); DOI.
- Müller, M. and others. Nitro-oleic acid enhances mitochondrial metabolism and ameliorates heart failure with preserved ejection fraction in mice. Nature Commun., 16, 3933 (2025); DOI.
- Murakami, C., Atsuta-Tsunoda, K., Inomata, S., Kawai, T., Hijikata, Y., Dilimulati, K., Sakai, H. and Sakane, F. Human PHOSPHO1 exhibits phosphatidylcholine- and phosphatidylethanolamine-phospholipase C activities and interacts with diacylglycerol kinase δ. FEBS Letts, 599, 1169-1186 (2025); DOI.
- Murakami, M. Secreted phospholipase A2 regulates intercellular communications by coordinating extracellular phospholipid metabolism. Int. Immun., 37, 599-610 (2025); DOI.
- Murakami, Y. Biosynthesis of GPI anchored proteins, its deficiencies and treatment. J. Human Gen., in press (2025); DOI.
- Nadhan, R., Nath, K., Basu, S., Isidoro, C., Song, Y.S. and Dhanasekaran, D.N. Decoding lysophosphatidic acid signaling in physiology and disease: mapping the multimodal and multinodal signaling networks. Signal Transd. Targ. Therapy, 10, 337 (2025); DOI.
- Nam, L.B., Kim, S.J., Nguyen, T.K., Jeong, C.Y., Lee, J.Y., Lee, J.S., Seo, J.T. and Moon, S.J. Cholesterol sulfate as a negative regulator of cellular cholesterol homeostasis. Molecules Cells, 48, 100209 (2025); DOI.
- Nasrallah, N., Atallah, M., Harb, T., Gerstenblith, G. and Leucker, T.M. Lipoprotein(a) in clinical practice: Risk stratification and therapeutic strategies. Eur. J. Clin. Invest., in press (2025); DOI.
- Nassini, R. and others. Targeting prostaglandin E2 receptor 2 in Schwann cells inhibits inflammatory pain but not inflammation. Nature Commun., 16, 8262 (2025); DOI.
- Navarro-Mabarak, C. and Morán, J. Molecular mechanisms of cytochrome P450-derived epoxy-fatty acids neuroprotection. Biochim. Biophys. Acta, Lipids, 1870, 159663 (2025); DOI.
- Neff, R.J. and Radka, C.D. Exploring oxylipins in host-microbe interactions and their impact on infection and immunity. Curr. Issues Mol. Biol., 47, 190 (2025); DOI.
- Ng, E.Z.Q., Lee, E., Chng, S.S., Kim, J. and Li Guan, X. Endogenous formation of phosphatidylhomoserine in Escherichia coli through phosphatidylserine synthase. J. Biol. Chem., 301, 110255 (2025); DOI.
- Ni, B., Klein, M., Hossbach, B., Feussner, K., Hornung, E., Herrfurth, C., Hamberg, M. and Feussner, I. Arabidopsis GH3.10 conjugates jasmonates. Plant Biol., 27, 476-491 (2025); DOI.
- Nikolaenko, V., Vootukuri, R., Eaton, S., Hällqvist, J., Baldwin, T., Mills, K. and Heywood, W. Glucosylsphingosine affects mitochondrial function in a neuronal cell model. Commun. Biol., 8, 1260 (2025); DOI.
- Nishizato, Y., Okumura, T., Matsumoto, K. and Ueda, M. Recent advances in the chemistry and biology of plant oxylipin hormones. Nat. Prod. Rep., 42, 1175-1194 (2025); DOI.
- Niu, Y. and Balla, T. The inner nuclear membrane has a unique lipid signature. Bioessays, 47, e70055 (2025); DOI.
- Noguchi, N., Saito, Y. and Niki, E. Lipid peroxidation, ferroptosis, and antioxidants. Free Rad. Biol. Med., 237, 228-238 (2025); DOI.
- Niu, Y. and Balla, T. The inner nuclear membrane has a unique lipid signature. Bioessays, 47, e70055 e70055 (2025); DOI.
- Noguchi, S., Boeglin, W.E., Nakashima, F., Stec, D.F., Calcutt, M.W., Takeichi, T., Akiyama, M. and Brash, A.R. The origin of hydroxy-cyclohexenone fatty acids from skin barrier protein and relevance to covalent binding of ceramides. J. Lipid Res., 66, 100843 (2025); DOI.
- O'Donnell, V.B. Recent updates in mammalian oxylipin biochemistry. J. Biol. Chem., 301, 110629 (2025); DOI.
- Obana, A. Measurement of skin carotenoids and their association with diseases: a narrative review. Biochim. Biophys. Acta, Lipids, 1870, 159612 (2025); DOI.
- Ohba, Y., Motohashi, M. and Arita, M. Characterization of UGT8 as a monogalactosyl diacylglycerol synthase in mammals. J. Biochem., 177, 141-152 (2025); DOI.
- Ohhara, Y., Sato, A., Hirono-Hara, Y., Hara, K.Y. and Yamakawa-Kobayashi, K. Evolution of a horizontally acquired fatty acid desaturase enables the biosynthesis of omega-3 polyunsaturated fatty acids in Collembola. Insect Biochem. Mol. Biol., 183, 104381 (2025); DOI.
- Oleszycka, E., Kwiecien, K., Grygier, B., Cichy, J. and Kwiecinska, P. The many faces of DGAT1. Life Sci., 362, 123322 (2025); DOI.
- Oliw, E.H. Structural comparisons of bifunctional fatty acid dioxygenases with allene oxide, epoxy alcohol, or diol synthase activities. Arch. Biochem. Biophys., 771, 110490 (2025); DOI.
- Oliw, E.H. Catalytic and structural comparisons of fatty acid dioxygenases related to cyclooxygenases and peroxidases. Arch. Biochem. Biophys., 773, 110574 (2025); DOI.
- Omidkhoda, S.F., Rajabian, F. and Hosseinzadeh, H. Lipoic acid as a protective agent against lipopolysaccharide and other natural toxins: a comprehensive review. Naunyn-Schmiedebergs Arch. Pharmacol., 398, 12811-12829 (2025); DOI.
- Ostermeyer-Fay, A.G., Kanodia, A., Pathak, R., Hernandez-Corbacho, M.J., van der Spoel, A.C., Hannun, Y.A. and Canals, D. The steady-state level of plasma membrane ceramide is regulated by neutral sphingomyelinase 2. J. Lipid Res., 66, 100719 (2025); DOI.
- Oubohssaine, M., Hnini, M. and Rabeh, K. Phospholipid signaling in plant growth and development: Insights biotechnological implications and future directions. J. Plant Physiol., 307, 154454 (2025); DOI.
- Ouyang, Z.W., Tan, Z.D., Ali, U., Zhang, Y., Li, B., Yao, X., Yang, B. and Guo, L. Ceramide-1-phosphate enhances defense responses against Sclerotinia sclerotiorum in Brassica napus. Plant Physiol., 197, kiae649 (2025); DOI.
- Pan, H.M., Su, H.G. and Huang, X. New players on lipid droplets: Their regulations and functions. Curr. Opinion Cell. Biol., 95, 102541 (2025); DOI.
- Pandi, A., Sen, N. and Kalappan, V.M. Fatty acid transport protein 2: A novel therapeutic target in lipid metabolism and disease - A review. Int. J. Biol. Macromol., 322, 146856 (2025); DOI.
- Paret, C. and others. Ganglioside profiling uncovers distinct patterns in high-risk neuroblastoma. Int. J. Mol. Sci., 26, 8431 (2025); DOI.
- Paul, S. and others. Modulation of endogenous plasmalogens by genetic ablation of lysoplasmalogenase (Tmem86b) in mice. J. Lipid Res., 66, 100808 (2025); DOI.
- Perera, S.D., Wang, J., Mcintyre, A.D. and Hegele, R.A. Lipoprotein lipase: structure, function, and genetic variation. Genes, 16, 55 (2025); DOI.
- Plouzennec, S., de la Barca, J.M.C. and Chevrollier, A. The role of phospholipids in mitochondrial dynamics and associated diseases. Front. Biosci.-Landmark, 30, 27634 (2025); DOI.
- Prottschiay, M.B. and others. Aspirin modulates generation of procoagulant phospholipids in cardiovascular disease by regulating LPCAT3. J. Lipid Res., 66, 100727 (2025); DOI.
- Pulica, R. and others. Dys-regulated phosphatidylserine externalization as a cell intrinsic immune escape mechanism in cancer. Cell Commun. Signal., 23, 131 (2025); DOI.
- Qian, C. and others. Arachidonic acid in aging: New roles for old players. J. Adv. Res., 70, 79-101 (2025); DOI.
- Qiu, H. and Ye, C.Q. Phospholipid biosynthesis: an unforeseen modulator of nuclear metabolism. Biol. Cell, 117, e70002 (2025); DOI.
- Quan, J., Zhang, C.H., Chen, X., Cai, X.F. and Luo, X.J. Lipid droplet - organelle crosstalk and its implication in cancer. Prog. Biophys. Mol. Biol., 197, 11-20 (2025); DOI.
- Quinlivan, K.M., Howard, I.V., Southan, F., Bayer, R.L., Torres, K.L., Serhan, C.N. and Panigrahy, D. Exploring the unique role of specialized pro-resolving mediators in cancer therapeutics. Prostaglandins Other Lipid Mediators, 178, 106944 (2025); DOI.
- Rajakumari, S. and Divakaran, S.J. EBF2 regulates cardiolipin and phosphatidylethanolamine remodeling and mitochondrial dynamics in brown fat. J. Lipid Res., 66, 100888 (2025); DOI.
- Rajha, H.E., Hassanein, A., Mesilhy, R., Nurulhaque, Z., Elghoul, N., Burgon, P.G., Al Saady, R.M. and Pedersen, S. Apolipoprotein A (ApoA) in neurological disorders: connections and insights. Int. J. Mol. Sci., 26, 7908 (2025); DOI.
- Rao, B.D. and others. Horizontal acquisition of prokaryotic hopanoid biosynthesis reorganizes membrane physiology driving lifestyle innovation in a eukaryote. Nature Commun., 16, 3291 (2025); DOI.
- Rao, D. and Wu, S.M. Food oxylipins: Formation, distribution, analysis and implications for health. Trends Food Sci. Techn., 159, 104968 (2025); DOI.
- Rao, Z.G. and others. Alkylglycerol monooxygenase represses prostanoid biosynthesis in a sex-dependent manner. Cell Biosci., 15, 80 (2025); DOI.
- Rapino, C., Standoli, S., Cencetti, F., Bruni, P., Oddi, S. and Maccarrone, M. New insights into the crosstalk between endocannabinoids and sphingosine-1-phosphate. J. Biol. Chem., 301, 110781 (2025); DOI.
- Rappoport, A. A lipid-raft theory of Alzheimer's disease. Annu. Rev. Biochem., 94, 387-416 (2025); DOI.
- Rashed, N., Liu, W.B. and Luo, X.J. The role of fatty acid oxidation in the tumor microenvironment: Implications for cancer progression and therapeutic strategies. Biochim. Biophys. Acta, Rev. Cancer, 1880, 189474 (2025); DOI.
- Rasmi, R.R., Kovatich, R., Farley, A., Sakthivel, K.M., Takiar, V. and Sertorio, M. Targeting SREBP2 in cancer progression: Molecular mechanisms, oncogenic crosstalk, and therapeutic interventions. Cell. Signal., 135, 112044 (2025); DOI.
- Reinisch, K.M., De Camilli, P. and Melia, T.J. Lipid dynamics at membrane contact sites. Annu. Rev. Biochem., 94, 479-502 (2025); DOI.
- Ren, M.D., Chen, S.Y., Greenberg, M.L. and Schlame, M. ABHD18 degrades cardiolipin by stepwise hydrolysis of fatty acids. J. Biol. Chem., 301, 110237 (2025); DOI.
- Ren, S.S. and others. Regulating arachidonic acid metabolism: a novel strategy to prevent colorectal inflammatory cancer transformation. J. Cancer, 16, 4155-4171 (2025); DOI.
- Revol-Cavalier, J., Quaranta, A., Newman, J.W., Brash, A.R., Hamberg, M. and Wheelock, C.E. The octadecanoids: synthesis and bioactivity of 18-carbon oxygenated fatty acids in mammals, bacteria, and fungi. Chem. Rev., 125, 1-90 (2025); DOI.
- Ribeiro, M., Alvarenga, L., Nascimento, D., Lima, L.S., Mafra, D. and Cardozo, L.F.M.F. Ceramides in non-communicable diseases: pathways, nutritional modulation, and therapeutic opportunities. J. Physiol. Biochem., in press (2025); DOI.
- Ridlon, J.M. and Gaskins, H.R. Another renaissance for bile acid gastrointestinal microbiology. Nat. Rev. Gastroenterol. Hepatol., 21, 348-364 (2024); DOI.
- Riley, N. and others. Dietary lipids are largely deposited in skin and rapidly affect insulating properties. Nature Commun., 16, 4570 (2025); DOI.
- Robles-Martinez, L., Morin, K.H. and Nikolova-Karakashian, M. Ceramide homeostasis in hepatic lipid droplets. Biochem. Soc. Trans., 53, 509-518 (2025); DOI.
- Rossignol, F., Lamari, F. and Mitchell, G.A. Phosphoinositide metabolism: biochemistry, physiology and genetic disorders. J. Inher. Metab. Dis., 48, e70008 (2025); DOI.
- Roussel, C., Lessard-Lord, J., Nallabelli, N., Muller, C., Flamand, N., Silvestri, C. and Di Marzo, V. Human gut microbes produce EPA- and DHA-derived oxylipins, but not N-acyl-ethanolamines, from fish oil. FASEB J., 39, e70713 (2025); DOI.
- Roychowdhury, R. and others. Jasmonic acid (JA) in plant immune response: unravelling complex molecular mechanisms and networking of defence signalling against pathogens. J. Plant Growth Regul., 44, 89-114 (2025); DOI.
- Rubbo, H. and Trostchansky, A. Nitro-fatty acid signaling: Therapeutic potential in inflammatory diseases. Redox Biochem. Chem., 8, 100027 (2025); DOI.
- Rufail, M.L., Bassi, R. and Giussani, P. Sphingosine-1-phosphate metabolic pathway in cancer: implications for therapeutic targets. Int. J. Mol. Sci., 26, 1056 (2025); DOI.
- Ruscica, M., Loh, W.J., Sirtori, C.R. and Watts, G.F. Phytosterols and phytostanols in context: From physiology and pathophysiology to food supplementation and clinical practice. Pharmacol. Res., 214, 107681 (2025); DOI.
- Saber, S.H. and others. DDHD2 provides a flux of saturated fatty acids for neuronal energy and function. Nature Metab., 7, 2117-2141 (2025); DOI.
- Sakane, F., Murakami, C. and Sakai, H. Upstream and downstream pathways of diacylglycerol kinase : Novel phosphatidylinositol turnover-independent signal transduction pathways. Adv. Biol. Reg., 95, 101054 (2025); DOI.
- Salomon, S., Oliva, O., Amato, A., Bastien, O., Michaud, M. and Jouhet, J. Betaine lipids: biosynthesis, functional diversity and evolutionary perspectives. Prog. Lipid Res., 97, 101320 (2025); DOI.
- Salsabila, S.D. and Kim, J. Structural insights into phosphatidylethanolamine N-methyltransferase PmtA mediating bacterial phosphatidylcholine synthesis. Sci. Adv., 10, eadr0122 (2025); DOI.
- Saqib, U. and others. Lipoxins as modulators of diseases. Cells, 14, 1244 (2025); DOI.
- Savulescu-Fiedler, I. and others. The cross-talk between the peripheral and brain cholesterol metabolisms. Curr. Issues Mol. Biol., 47, 115 (2025); DOI.
- Sawasato, K., Dowhan, W. and Bogdanov, M. Its own architect: Flipping cardiolipin synthase. Sci. Adv., 11, eads0244 (2025); DOI.
- Schmidt, T. and others. Roles of acyl carrier proteins in ladderane fatty acid producing-organisms. Biochim. Biophys. Acta, General Subjects, 1869, 130763 (2025); DOI.
- Schopfer, F.J., Teng, L.H., Sekandari, A., Ekhator, E.S., Kohan, A.B., Freeman, B.A. and Fazzari, M. Fatty acid nitroalkenes regulate intestinal lipid absorption. J. Lipid Res., 66, 100855 (2025); DOI.
- Serhan, C.N. and Levy, B.D. Proresolving lipid mediators in the respiratory system. Annu. Rev. Physiol., 87, 491-512 (2025); DOI.
- Shang, Z. and others. Self-resistance gene-guided discovery of the molecular basis for biosynthesis of the fatty acid synthase inhibitor cerulenin. Angew. Chem.-Int. Ed., Angew. Chem.-Int. Ed., 64, e202414941 (2025); DOI.
- Sharma, G., Badruddeen., Akhtar, J., Khan, M.I., Ahmad, M. and Sharma, P.K. Methyl jasmonate: bridging plant defense mechanisms and human therapeutics. Naunyn-Schmiedebergs Arch. Pharmacol., 398, 6429-6451 (2025); DOI.
- Shaw, A.L. and Burke, J.E. Molecular insight on the role of the phosphoinositide PIP3 in regulating the protein kinases Akt, PDK1, and BTK. Biochem. Soc. Trans., 53, 737-749 (2025); DOI.
- Shaw, A.L., Barlow-Busch, I. and Burke, J.E, Molecular basis for regulation of the class I phosphoinositide 3-kinases (PI3Ks), and their targeting in human disease. Biochim. Biophys. Acta, Lipids, 1870, 159689 (2025); DOI.
- Shen, X., Miao, S., Zhang, Y., Guo, X., Li, W., Mao, X. and Zhang, Q. Stearic acid metabolism in human health and disease. Clin. Nutr., 44, 222-238 (2025); DOI.
- Shen, X.P., Feng, R., Zhou, R., Zhang, Z.Y., Liu, K.Y. and Wang, S. Ceramide as a promising tool for diagnosis and treatment of clinical diseases: a review of recent advances. Metabolites, 15, 195 (2025); DOI.
- Sheokand, P.K. and others. RAM-LAG1-CLN8 family proteins are acyltransferases regulating phospholipid composition. Sci. Adv., 11, eadr3723 (2025); DOI.
- Shetty, V.V. and Shetty, S.S. Fatty acid desaturase: the yin or yang of disease pathology. Mol. Diagnosis Therapy, 29, 637-654 (2025); DOI.
- Shin, Y.H., Bang, S., Xavier, R. and Clardy, J. Eggerthella lenta produces a cryptic pro-inflammatory lipid. J. Am. Chem. Soc., 147, 25180-2518 (2025); DOI.
- Sikder, M.M. and others. PLAAT5 as an N-acyltransferase responsible for the generation of anti-inflammatory N-acylethanolamines in testis. Biochim. Biophys. Acta, Lipids, 1870, 159583 (2025); DOI.
- Simankowicz, P. and Stepniewska, J. The role of endocannabinoids in physiological processes and disease pathology: a comprehensive review. J. Clin. Med., 14, 2851 (2025); DOI.
- Sokol, K.H. and others. Lipid availability influences ferroptosis sensitivity in cancer cells by regulating polyunsaturated fatty acid trafficking. Cell Chem. Biol. 32, 408-422 (2025); DOI.
- Sol, J. and others. Ether lipids and sphingolipids drive sex-specific human aging dynamics. Redox Biol., 85, 103779 (2025); DOI.
- Sonkar, K. and Singh, A. Metabolic and physiological functions of Patatin-like phospholipase-A in plants. Int. J. Biol. Macromol., 287, 138474 (2025); DOI.
- Sousa, LG., Correia-da-Silva, G., Teixeira, N. and Fonseca, B.M. Specialized pro-resolving mediators: key regulators in placental function and pregnancy complications. J. Mol. Med., 103, 885-897 (2025); DOI.
- Starikov, A.Y., Sidorov, R.A. and Los, D.A. Counting modes of acyl-lipid desaturases. Funct. Plant Biol., 52, FP24338 (2025); DOI.
- Starikov, A.Y., Sidorov, R.A., Kazakov, G., Leusenko, P.A. and Los, D.A. The substrate preferences and counting mode of the cyanobacterial w3 (D15) acyl-lipid desaturase. Biochimie, 232, 74-82 (2025); DOI.
- Stea, D.M. and D'Alessio, A. Caveolae: metabolic platforms at the crossroads of health and disease. Int. J. Mol. Sci., 26, 2918 (2025); DOI.
- Stonik, V.A., Makarieva, T.N., Shubina, L.K., Guzii, A.G. and Ivanchina, N.V. Structure diversity and properties of some bola-like natural products. Marine Drugs, 23, 3 (2025); DOI.
- Su, H., Li, Y., Li, Z.P., Li, SM., Pan, J.S., Ji, G., Lu, L. and Xu, H.C. Ceramides and associated key enzymes at the evolutionary crossroad of colorectal inflammatory immune responses and tumorigenesis. Int. J. Biol. Macromol., 322, 146916 (2025); DOI.
- Sugimoto, Y., Aikawa, S., Inazumi, T. and Hirota, Y. Roles of prostaglandin signaling in implantation and decidualization. Prog. Lipid Res., 100, 101357 (2025); DOI.
- Suo, Y.X., Jiang, Z.R., Heberlig, G.W., Wang, E.Y., Sankaran, B., La Clair, J.J. and Burkart, M.D. Role of human mitochondrial ketosynthase in long-chain fatty acid biosynthesis. J. Am. Chem. Soc., 147, 33248-33255 (2025); DOI.
- Suzuki, H., Cuiné, S., Légeret, B., Wijffels, R.H., Hulatt, C.J., Li-Beisson, Y. and Kiron, V. Phosphorus starvation induces the synthesis of novel lipid class diacylglyceryl glucuronide and diacylglyceryl-N,N,N-trimethylhomoserine in two species of cold-adapted microalgae Raphidonema (Chlorophyta). Plant J., 121, e17227 (2025); DOI.
- Suzuki, T., Taketomi, Y., Yanagida, K., Yoshida-Hashidate, T., Nagase, T., Murakami, M., Shimizu, T. and Shindou, H. Re-evaluation of the canonical PAF pathway in cutaneous anaphylaxis. Biochim. Biophys. Acta, Lipids, 1870, 159563 (2025); DOI.
- Svistunov, V.O., Ehrmann, K.J., Lencer, W.I. and Schmieder, S.S. Sorting of complex sphingolipids within the cellular endomembrane systems. Front. Cell Developm. Biol., 12, 1490870 (2025); DOI.
- Tamazawa, A., Naganuma, T., Otsuka, K., Takahashi, T., Sassa, T. and Kihara, A. Fatty acyl-CoA reductase FAR1 is essential for the testicular seminolipid synthesis required for spermatogenesis and male fertility. J. Biol. Chem., 301, 108538 (2025); DOI.
- Tan, D. and Saghatelian, A. The measurement, regulation and biological activity of FAHFAs. Nature Chem. Biol., 21, 796-806 (2025); DOI.
- Tan, R.L. and others. CDP-DAG synthases regulate plant growth and broad-spectrum disease resistance. Plant Signal. Behavior, 20, 2471503 (2025); DOI.
- Tang, J.B., Li, X.H., Li, W. and Cao, C. The protective effect of octanoic acid on sepsis: a review. Nutr. Rev., 83, e1270-e1285 (2025); DOI.
- Tao, Y., Sun, Y.L., Chai, Y.D., Duma, L. and Rossez, Y. Fatty acid desaturases in non-photosynthetic bacteria: classification, regulation, and roles in plasma membrane function and cellular homeostasis. Biochim. Biophys. Acta, Lipids, 1870, 159630 (2025); DOI.
- Teng, Y.Y., Xue, H.P., Deng, X.L., Luo, Y.Q. and Wu, T. The role of phosphatidylethanolamine-binding protein (PEBP) family in various diseases: Mechanisms and therapeutic potential. Progr Biophys. Mol. Biol., 196, 102-113 (2025); DOI.
- Teyani, R.L. and Moniri, N.H. Biased agonism at free-fatty acid receptor-4 (FFA4/GPR120). Pharmacol. Therapeut., 266, 108784 (2025); DOI.
- Thakkar, H., Vincent, V. and Chaurasia, B. Ceramide signaling in immunity: a molecular perspective. Lipids Health Dis., 24, 225 (2025); DOI.
- Thatavarthy, S. and others. Cardiolipin dynamics promote membrane remodeling by mitochondrial OPA1. Nature Commun., 16, 8685 (2025); DOI.
- Tian, C. and Wang, Q. Protein prenylation in plants: mechanisms and functional implications. Plants-Basel, 14, 1759 (2025); DOI.
- Tredicine, M., Mucci, M., Recchiuti, A. and Mattoscio, D. Immunoregulatory mechanisms of the arachidonic acid pathway in cancer. FEBS Letts, 599, 927-951 (2025); DOI.
- Tsap, M.I. and Shcherbata, H.R. The balancing act between lipid droplets and lysosomes for membrane functionality in age-related neurodegeneration and inflammation. Prog. Lipid Res., 99, 101341 (2025); DOI.
- Tsujimura, K., Yakabe, M., Kano, H. and Matsumori, N. Apoptosis induction by ceramide derivatives and its potential mechanisms through domain formation. Bioorg. Med. Chem., 126, 118222 (2025); DOI.
- Umair, Z., Nawaz, Z., Hasnain, S. and Fischle, W. The oily nucleus- role of phospholipids in genome biology: membrane-directed roles and signaling in the nucleoplasm. Cell. Mol. Life Sci., 82, 286 (2025); DOI.
- Umar, A.W., Hussain, H. and Ahmad, N. The known unknowns: an enigmatic pathway of C17-polyacetylenic oxylipins in carrot (Daucus carota L.) Curr. Issues Mol. Biol., 47, 471 (2025); DOI.
- Uyama, T., Sasaki, S., Okada-Iwabu, M. and Murakami, M. Recent progress in N-acylethanolamine research: biological functions and metabolism regulated by two distinct N-acyltransferases: cPLA2ε and PLAAT enzymes. Int. J. Mol. Sci., 26, 3359 (2025); DOI.
- Uyama, T., Sasaki, S., Sikder, M.M., Okada-Iwabu, M. and Ueda, N. The PLAAT family as phospholipid-related enzymes. Prog. Lipid Res., 98, 101331 (2025); DOI.
- Vafaee, F., Derakhshani, M., Rahbardar, M.G. and Hosseinzadeh, H. Alpha-lipoic acid, as an effective agent against toxic elements: a review. Naunyn-Schmiedebergs Arch. Pharmacol., 398, 3345-3372 (2025); DOI.
- Valkenburg, A.D., Ncube, M.Z., Teke, G.M., van Rensburg, E. and Pott, R.W.M. Cellobiose lipids: applications, production, and downstream processing. Trends Biotechn., 43, 555-571 (2025); DOI.
- Vanauberg, D. and others. O-GlcNAcylation of fatty acid synthase is required for its proper subcellular localization, expression level, and activity. J. Biol. Chem., 301, 110497 (2025); DOI.
- Vásquez, A., Leidy, C. and Manrique-Moreno, M. Lysyl-phosphatidylglycerol: a lipid involved in the resistance of Staphylococcus aureus to antimicrobial peptide activity. Antibiotics-Basel, 14, 349 (2025); DOI.
- Vaz, F.M., Ferdinandusse, S., Salomons, G.S. and Wanders, R.J.A. Disorders of fatty acid homeostasis. J. Inher. Metab. Dis., 48, e12734 (2025); DOI.
- Victoria, V.M., Constanza, P.M., Victoria, G.M., Virginia, S.P., Jose, L., Gustavo, B. and Cecilia, S.M. Nitro-Oleic acid protects from neovascularization, oxidative stress, gliosis and neurodegeneration in oxygen-induced retinopathy. Redox Biol., 83, 103634 (2025); DOI.
- Viña, I. and López-Moreno, M Meta-analysis of palmitoylethanolamide in pain management: addressing literature gaps and enhancing understanding. Nutr. Rev., 83, e1604-e1618 (2025); DOI.
- Visser, A., Hussain, M.M. and Kuivenhoven, J.A. The intracellular chylomicron highway: novel insights into chylomicron biosynthesis, trafficking, and secretion. Curr. Opinion Lipidol., 36, 145-152 (2025); DOI.
- Voss, J., Hornemann, T. and Belgardt, B. Impact of nutrition on sphingolipid-regulated physiology: a review. Mol. Nutr. Food Res., e70182 (2025); DOI.
- Vyssotski, M., Lagutin, K., Mackenzie, A., Mitchell, K., Stewart, A.W., Scott, D., Stott, M.B. and Compton, B.J. Serinophospholipids: a third type of natural phospholipid discovered in a thermophilic bacterium. J. Nat. Prod., in press (2025); DOI.
- Wang, H., Liu, D. and Zhou, X. Effect of mycolic acids on host immunity and lipid metabolism. Int. J. Mol. Sci., 25, 396 (2024); DOI.
- Wang, H.N., Wang, Y., Zhang, S.Y. and Bai, L. Emerging roles of the acid sphingomyelinase/ceramide pathway in metabolic and cardiovascular diseases: Mechanistic insights and therapeutic implications. World J. Cardiol., 17, 102308 (2025); DOI.
- Wang, K., Feng, Y., Ma, F., Li, J.J., Chen, J. and Ma, X. The role of gangliosides in male reproduction. Glycobiology, 35, cwaf036 (2025); DOI.
- Wang, S.N., Jin, Z.H., Wu, B.Y., Morris, A.J. and Deng, P. Role of dietary and nutritional interventions in ceramide-associated diseases. J. Lipid Res., 66, 100726 (2025); DOI.
- Wang, Y., Guo, J., Mao, Z.Q. and Chen, Y. Symphony of the gut microbiota and endocannabinoidome: a molecular and functional perspective. Front. Cell. Infect. Microbiol., 15, 1566290 (2025); DOI.
- Wang, Y.N. and Liu, S.Y. The role of ALDHs in lipid peroxidation-related diseases. Int. J. Biol. Macromol., 288, 138760 (2025); DOI.
- Wang, Y.P., Sanyal, A.J., Hylemon, P. and Ren, S.L. Discovery of a novel regulator, 3β-sulfate-5-cholestenoic acid, of lipid metabolism and inflammation. Am. J. Physiol., Endocrin. Metab., 328, E543-E554 (2025); DOI.
- Wang, Z., Gao, H.Y., Ma, X.T., Zhu, D.L., Zhao, L.L. and Xiao, W.H. Adrenic acid: A promising biomarker and therapeutic target (Review). Int. J. Mol. Med., 55, 20 (2025); DOI.
- Wang, Z.Y., Li, X.Y. and Sun, X.Y. Targeting cholesterol metabolism in tumor and its immune microenvironment: opportunities and challenges. Biochim. Biophys. Acta, Rev. Cancer, 1880, 189422 (2025); DOI.
- Warda, M., Tekin, S., Gamal, M., Khafaga, N., Çelebi, F. and Tarantino, G. Lipid rafts: novel therapeutic targets for metabolic, neurodegenerative, oncological, and cardiovascular diseases. Lipids Health Dis., 24, 147 (2025); DOI.
- Watanabe, Y., Kumeta, H. and Watanabe, S. Structural basis for phosphatidylcholine synthesis by bacterial phospholipid N-methyltransferases. J. Biol. Chem., 301, 108507 (2025); DOI.
- Wei, W., Wang, L.F., Tao, J.J., Zhang, W.K., Chen, S.Y., Song, Q.X. and Zhang, J.S. The comprehensive regulatory network in seed oil biosynthesis. J. Integr. Plant Biol., 67, 649-66 (2025); DOI.
- Welcome, F.S., Elizaire, T.C.M. and Airola, M. Lipin phosphatidic acid phosphatases: Structure, function, regulation, and disease association. Adv. Biol. Reg., 96, 101082 (2025); DOI.
- Wertz, P.W. A provocation on formation of the corneocyte lipid envelope. Skin Pharmacol. Physiol., 38, 59-164 (2025); DOI.
- Weske, S. and others. Intracellular sphingosine-1-phosphate induces lipolysis through direct activation of protein kinase c zeta. FASEB J., 39, e70528 (2025); DOI.
- Wijesinghe, G.K., Nobbs, A.H. and Bandara, H.M.H.N. The diffusible signaling factor family in microbial signaling: a current perspective. Crit. Rev. Microbiol., 27, 1-16 (2025); DOI.
- Wiley, A.M. and others. Selective knockdown of ceramide synthases reveals opposite roles of different ceramide species in cardiac homeostasis. Metabolites, 15, 584 (2025); DOI.
- Williams, D.M. and Peden, A.A. Greasing the wheels of inflammasome formation: regulation of NLRP3 function by S-linked fatty acids. Biochem. Soc. Trans., 53, BST20241738 (2025); DOI.
- Wu, C.T., Lin, J.J., Chen, Q.K., Zhao, W.X., Kawahata, I. and Cheng, A. Targeting the FABP axis: interplay between lipid metabolism, neuroinflammation, and neurodegeneration. Cells, 14, 1502 (2025); DOI.
- Wu, Y., Deng, Y.R., Angelov, B. and Angelova, A. Plasmalogen as a bioactive lipid drug: from preclinical research challenges to opportunities in nanomedicine. FASEB Bioadv., 7, e70028 (2025); DOI.
- Wu, Y.M., Song, W.Q., Su, M., He, J., Hu, R. and Zhao, Y.B. The role of cholesterol metabolism and its regulation in tumor development. Cancer Med., 14, e70783 (2025); DOI.
- Wuerch, E.C. and Yong, V.W. Cholesterol in the CNS: functions, recycling and remyelination. J. Neuroinflamm., 22, 180 (2025); DOI.
- Wundersitz, A., Hoffmann, K.M.V. and van Dongen, J.T. Acyl-CoA-binding proteins: bridging long-chain acyl-CoA metabolism to gene regulation. New Phytol., 246, 1960-1966 (2025); DOI.
- Xiang, F., Zhang, Z.M., Xie, J.C., Xiong, S.H., Yang, C., Liao, D.F., Xia, B.H., Lin, L.M. Comprehensive review of the expanding roles of the carnitine pool in metabolic physiology: beyond fatty acid oxidation. J. Transl. Med., 23, 324 (2025); DOI.
- Xie, M. and others. Structure and pH dependence of membranolytic mechanisms by truncated oxidized phospholipids. J. Am. Chem. Soc., 147, 9175-9189 (2025); DOI.
- Xie, S.J. and others. Globotriaosylceramide Gb3 influences wound healing and scar formation by orchestrating fibroblast heterogeneity. Adv. Sci., 12, e09733 (2025); DOI.
- Xu, G.W., Xiao, W., Sun, P.Q., Sun, Y.J., Yang, X.Y., Yin, X.M. and Liu, Y. Lysophosphatidylethanolamine improves diastolic dysfunction by alleviating mitochondrial injury in the aging heart. J. Lipid Res., 66, 100713 (2025); DOI.
- Xu, M.K. and Xu, B. Protein lipidation in the tumor microenvironment: enzymology, signaling pathways, and therapeutics. Mol. Cancer, 24, 138 (2025); DOI.
- Xu, R.C., Molenaar, A.J., Chen, Z. and Yuan, Y. Mode and mechanism of action of omega-3 and omega-6 unsaturated fatty acids in chronic diseases. Nutrients, 17, 1540 (2025); DOI.
- Xu, Z. and others. Sphingosine-1-phosphate signalling activates E-Syt1 to facilitate HDL-derived cholesterol transport. Nature Cell Biol., 27, 918-930 (2025); DOI.
- Yadav, R., Obinata, H. and Venkataraman, K. Delineating the intricacies of polymorphisms, structures, functions and therapeutic applications of biological high-density lipoprotein-apolipoprotein M: A review. Int. J. Biol. Macromol., 310, 143187 (2025); DOI.
- Yaghmour, M.H., Sajeevan, T., Thiele, C. and Kuerschner, L. Phosphatidylcholine synthesis and remodeling in brain endothelial cells. J. Lipid Res., 66, 100773 (2025); DOI.
- Yamaga, M. and Martin, T.F.J. PI(4,5)P2 is a master regulator for Ca2+-triggered vesicle exocytosis. Biochim. Biophys. Acta, Lipids, 1870, 159651 (2025); DOI.
- Yang, B. and others. Regulation of glucosylceramide synthase and sphingolipid remodeling in the plant response to phosphate deficiency. Plant Cell, 37, koaf138 (2025); DOI.
- Yang, B., Fan, R.Y., Yao, S.B., Lou, H.X., Li, J.W., Guo, L. and Wang, X.M. Non-specific phospholipase Cs and their potential for crop improvement. J. Exp. Botany, in press (2025); DOI.
- Yang, C., Lai, Y.M. and Yao, N. Plant sphingolipids: Subcellular distributions and functions. Curr. Opinion Plant Biol., 85, 102704 (2025); DOI.
- Yang, G. and others. CHP1 promotes lipid droplet growth and regulates the localization of key enzymes for triacylglycerol synthesis. Proc. Natl. Acad. Sci. USA, 122, e2508912122 (2025); DOI.
- Yang, J., Zhong, W.Y., Li, Q.Q., Zhang, W., Lin, W.Y., Fan, X.M., He, Y.J. and Ma, N. Sphingosine-1-phosphate signaling in respiratory diseases: mechanisms and therapeutic perspectives. Int. Immunopharm., 166, 115578 (2025); DOI.
- Yang, W., Feng, X., Chen, H.H., Liman, G.L.S., Santangelo, T.J., Zhang, C.Y. and Zeng, Z.R. Cyclization of archaeal membrane lipids impacts membrane protein activity and archaellum formation. Proc. Natl. Acad. Sci. USA, 122, 2423648122 (2025); DOI.
- Yang, X.R., Tu, Y.B., Liang, N., Li, L.L., Zhang, J., Xu, J.Y. and Li, C.M. Lp-PLA2 in the cancer landscape: From molecular mechanisms to therapeutic potential (Review). Int. J. Oncol., 67, 87 (2025); DOI.
- Yao, J., Xie, C.Y. and Yang, A.M. The emerging roles of S-acylation in autophagy. Trends Biochem. Sci., 50, 744-747 (2025); DOI.
- Yao, S.B., Yang, B., Li, J.W., Tang, S., Tang, S.H., Kim, S.C. and Wang, X.M. Phosphatidic acid signaling in modulating plant reproduction and architecture Plant Commun., 6, 101234 (2025); DOI.
- Yoo, Y., Yeon, M., Yoon, M.S. and Seo, Y.K. Role of cardiolipin in skeletal muscle function and its therapeutic implications. Cell Commun. Signal., 23, 36 (2025); DOI.
- You, Y.F., Zeng, Q.H., Hu, Z.Y., Chen, Y., Zhan, M.M., Wang, Y.L. and Duan, J.J. Myristic acid remodels sphingolipid metabolism via dual pathways: canonical d18-sphingolipid regulation and non-canonical d16-sphingolipid synthesis. Nutrients, 17, 2881 (2025); DOI.
- Yu, P.X., Orlando, M.A. and Orlando, B.J. Structure and post-translational modification of the prostaglandin transporter. Commun. Biol., 8, 1066 (2025); DOI.
- Yu, X.Q., Lei, S.M., Shen, Y., Liu, T., Li, J., Wang, J. and Su, Z.G. Cholesterol sulfate: pathophysiological implications and potential therapeutics. Biomolecules, 15, 646 (2025); DOI.
- Yue, Z.J., Li, X.R., Shi, Z. and Li, X.W. Myocardial ferroptosis may exacerbate the progression of atrial fibrillation through isolevuglandins. Eur. J. Med. Res., 30, 93 (2025); DOI.
- Yui, K., Imataka, G. and Ichihashi, M. Prostaglandins: biological action, therapeutic aspects, and pathophysiology of autism spectrum disorders. Curr. Issues Mol. Biol., 47, 71 (2025); DOI.
- Yuksel, S. and Butovich, I.A. Biosynthesis of fatty aldehydes and alcohols in the eye and their role in meibogenesis. J. Biol. Chem., 301, 110330 (2025); DOI.
- Zapi-Colín, L.A., Dotor-Hernández, J.E., Contreras, I. and Estrada, J.A. Arachidonoylethanolamide promotes cellular senescence in a human glioblastoma cell line. Biochem. Biophys. Res. Commun., 745, 151235 (2025); DOI.
- Zbylicki, B.R., Cochran, S., Weiss, D.S. and Ellermeier, C.D. Identification of two glycosyltransferases required for synthesis of membrane glycolipids in Clostridioides difficile. mBio, 16, e0351224 (2025); DOI.
- Zeng, F.S., Heier, C., Yu, Q., Pang, H.M., Huang, F.F., Zhao, Z. and Chang, P.A. Human transmembrane protein 68 links triacylglycerol synthesis to membrane lipid homeostasis. FEBS J., 292, 2935-2952 (2025); DOI.
- Zerun, J. and Bajguz, A. Around the brassinosteroids in algae. Algal Res., Biomass Biofuels Bioprod., 85, 103881 (2025); DOI.
- Zhang, H.J., Yu, F.Z., Tian, Z.J. and Jia, D.D. Cardiolipin remodeling in cardiovascular diseases: implication for mitochondrial dysfunction. Acta Physiol., 241, e70073 (2025); DOI.
- Zhang, H.S., Feng, T.H. and Chang, Q.X. Impact of molecular regulation on plant oil synthesis. Plant Sci., 354, 112428 (2025); DOI.
- Zhang, J.W., Wu, S.Y., Xu, Y.T., Zhang, L., Cong, C., Zhang, M.H., Jiang, Y.H. and Liu, Y. Lipid overload meets S-palmitoylation: a metabolic signalling nexus driving cardiovascular and heart disease. Cell Commun. Signal., 23, 392 (2025); DOI.
- Zhang, L., Wang, X. and Chen, X.-W. The biogenesis and transport of triglyceride-rich lipoproteins. Trends Endocrin. Metab., 36, 262-277 (2025); DOI.
- Zhang, L.L., Duan, W.X. and Li, .LY. Phosphatidylethanolamine: A key player in lung disease. Clin. Transl. Disc., 5, e70076 (2025); DOI.
- Zhang, L.Q., Wang, X. and Chen, X.W. The biogenesis and transport of triglyceride-rich lipoproteins. Trends Endocrinol. Metab., 36, 262-277 (2025); DOI.
- Zhang, X., Zhang, X.C., Lin, L., Wang, K.F. and Ji, X.J. Advances in the biosynthesis of tetraacetyl phytosphingosine, a key substrate of ceramides. Synth. Systems Biotechn., 10, 1-9 (2025); DOI.
- Zhang, Y.C., Chen, Y.Q., Zhuang, C., Qi, J.X., Zhao, R.C. and Wang, J. Lipid droplets in the nervous system: involvement in cell metabolic homeostasis. Neural Regen. Res., 20, 740-750 (2025); DOI.
- Zhang, Y.L., Wu, W.Z. and Chen, Z. Dual roles of prostaglandin E2 (PGE2) in bone remodeling and pain management: bridging the gap in osteoarthritis research. Med. Inflamm., 2025, 8882429 (2025); DOI.
- Zhao, M.T., Liu, Z.Y., Zhang, W.L., Xia, G.H., Li, C., Rakariyatham, K. and Zhou, D.Y. Advance in aldehydes derived from lipid oxidation: A review of the formation mechanism, attributable food thermal processing technology, analytical method and toxicological effect. Food Res. Int., 203, 115811 (2025); DOI.
- Zhao, Q., Duan, Z.L., Lai, R. and Ma, P.C. Novel microbially transformed bile acids: Biosynthesis, structure, and function. Pharmacol. Res., 216, 107775 (2025); DOI.
- Zhao, Y.J., Cao, R., Li, J.C., Xu, Y.Y., Zhou, L.J. and Ye, Y.J. Lipid droplets in plants: turnover and stress responses. Front. Plant Sci., 16, 1625830 (2025); DOI.
- Zheng, C., Chen, J.P., Wang, X.W. and Li, P. Reactive oxygen species in plants: metabolism, signaling, and oxidative modifications. Antioxidants, 14, 617 (2025); DOI.
- Zheng, J.S. and Conrad, M. Ferroptosis: when metabolism meets cell death. Physiol. Rev., 105, 651-706 (2025); DOI.
- Zhu, J.J. and others. Divergent fatty acid desaturase 2 is essential for falcarindiol biosynthesis in carrot. Plant Commun., 6, 101323 (2025); DOI.
- Zhu, J.Z., Wang, Y.J., Zhu, K.P. and Zhang, C.L. Advances in understanding the role of squalene epoxidase in cancer prognosis and resistance. Mol. Biol. Rep., 52, 162 (2025); DOI.
- Zhu, S., He, Y., Lei, J.N., Liu, Y.F. and Xu, Y.J. The chemical and biological characteristics of fatty acid esters of hydroxyl fatty acids. Nutr. Rev., 83, e427-e442 (2025); DOI.
- Zhu, Y.Q., Cho, K.V., Lacin, H., Zhu, Y., DiPaola, J.T., Wilson, B.A., Patti, G. and Skeath, J.B. Loss of dihydroceramide desaturase drives neurodegeneration by disrupting endoplasmic reticulum and lipid droplet homeostasis in glial cells. eLife, 13, RP99344 (2025); DOI.
- Zhuang, T.X. and others. Biological functions and pharmacological behaviors of bile acids in metabolic diseases. J. Adv. Res., 75, 779-792 (2025); DOI.
| © Data compiled by Bill Christie | ![]() |
|
| Updated: December 2025 | Contact/credits/disclaimer | |
