Lipid Essentials Literature - Highlights - Latest Month

This list was created by means of a weekly literature search with a highly subjective scan to select those papers that appeared helpful to me for updating the Lipid Essentials or Blog pages on this site. They are mainly review articles dealing with the chemistry, occurrence and biochemistry of lipids, and the nutritional/clinical literature is under represented here. They are culled from a scan of ~1500 titles each month. Please note that I may only select references from journals to which I have direct access, or will have access after a period specified by the journal (usually 6 to 24 months). Some papers in press may be listed here without the full citation, but the DOI address should still be valid, and they may be updated later. References are listed alphabetically by the first author.

References Collected in November 2025

Alemany, C. and Morel, E. Phosphoinositides in membrane remodeling during infections and cellular stresses. FEBS Letts, in press (2025); DOI.
Baek, O., Klabunde, B., Wang, T.T., Bonnelykke, K., Stokholm, J., Brustad, N., Nguyen, D.N. and Chawes, B. A scoping review on the possible immunometabolic properties of the furan fatty acid metabolite 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid. Am. J. Clin. Nutr., 122, 1155-1160 (2025); DOI.
Cater, M., Simon, M., Morton, N.M., Kunej, T. and Horvat, S. PLA2G4E in health and disease: Insights from omics and functional analyses. Prog. Lipid Res., 100, 101359 (2025); DOI.
Chen, Y.S., Wu, X.W., Li, J.Q., Ren, Y.X., Miao, H., Zhai, X.J., Huang, C.S. and Chen, X.W. The mechanisms of specialized pro-resolving mediators in pain relief: neuro-immune and neuroglial regulations. Front. Immun., 16, 1634724 (2025); DOI.
Chiappa, NF., Lal, N. and Botchwey, E.A. Resolving versus non-resolving sphingolipid dynamics during macrophage activation: a time-resolved metabolic analysis. J Lipid Res., 66, 100899 (2025); DOI.
Chinnappa, K., Ballorin, F. and Francis, F. Fundamental neurochemistry review: sphingolipids and ceramides in brain development. J. Neurochem., 169, e70262 (2025); DOI.
Chistyakov, D.V., Chistyakov, V.V. and Sergeeva, M.G. Oxylipins in atherosclerosis: their role in inflammation, diagnosis, and therapeutic perspectives. Int. J. Mol. Sci., 26, 10577 (2025); DOI.
Damsté, J.S.S., Koenen, M., Thiel, V., Richter, N., Hopmans, E.C. and Nicole J. Bale, N.J. A comprehensive study of biohopanoid production in Alphaproteobacteria: biosynthetic, chemotaxonomical, and geobiological implications. Geobiology, 23, e70038 (2025); DOI.
Debédat, J., Pastor, L., Knotts, T.A., Pitman, J.G., Griffett, K. and Adams, S.H. Cyclopropane xenolipids resemble monounsaturated fatty acids and modulate peroxisome proliferator-activated receptors, J. Lipid Res., 66, 100896 (2025); DOI.
Dedoni, S., Avdoshina, V., Olianas, M.C. and Onali, P. Role of lysophosphatidic acid in neurological diseases: from pathophysiology to therapeutic implications. Front. Biosci.-Landmark, 30, 28245 (2025); DOI.
Elhan, H and others. ATG2A-mediated DAG transfer recruits DGAT2 for lipid droplet growth. Nature Struct. Mol. Biol., in press (2025); DOI.
Gorina, S.S., Lantsova, N., Iljina, T.M., Toporkova, Y.Y., Grechkin, A.N. Arabidopsis AtCYP71B23: Detection of non-CYP74 enzyme of oxylipin biosynthesis. Biochim. Biophys. Acta, Lipids, 1871, 159699 (2026); DOI.
Guo, S.R., Li, X.Y., Xun, M., He, Y.L., Tai, A.W. and Wang, H.L. Disrupted glycosylphosphatidylinositol anchoring induces ER stress and restricts enterovirus infection. PLOS Path., 21, e1013685 (2025); DOI.
Hou, Y. C. and others. Newcastle disease virus acquires phosphatidylserine through the budding process to enhance infectivity. Virulence, 16, 2580150 (2025); DOI.
Iraji, R. and others. Homeostatic response of phospholipid pathways to PCYT2 deficiency and impaired de novo synthesis of phosphatidylethanolamine. Sci. Rep., 15, 38747 (2025); DOI.
Koh, Y.C., Kamchonemenukool, S., Ho, P.Y., Weerawatanakorn, M. and Pan, M.H. Oleic acid-esterified octacosanol as a functional ingredient to counter obesity-associated lipid dysregulation through PPAR-targeted regulation. J. Agric. Food Chem., in press (2025); DOI.
Krishnan, H., Venugopal, A., Alex, P. and Raghu, P. The multifaceted phosphatidylinositol 5 phosphate 4-kinase proteins: molecular properties and biological functions. Biochim. Biophys. Acta, Lipids, 1871, 159698 (2026); DOI.
Lai, S.Y., Huang, W.B. and He, K.M. Spatial organization of phosphoinositide signaling. FEBS Letts, in press (2025); DOI.
Lange, M. and others. FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis. Nature Cell Biol., 27, 1902-1913 (2025); DOI.
Li, X., Li, Z.Q., Chiang, Y.P., Worgall, T., Souaiaia, T. and Jiang, X.C. Sphingomyelin synthase-related protein is a regulator of serine palmitoyltransferase. J. Lipid Res., 66, 100908 (2025); DOI.
Li, Y.H., Gao, X.L., Gao, Z.A., Cao, Z.H., Xiong, P. and Liu, X.T. Sources and biological functions of nervonic acid: Advances and perspectives. Chem. Phys. Lipids, 273, 105554 (2025); DOI.
Li, Y.Y. and others. 12-HETE Is an endogenous modulator of BLT2 triggering vascular degeneration, dissection, and rupture. Adv. Sci., in press (2025); DOI.
Liu, C.X., Zhang, X.Y., Wu, W.X. and Song, T.X. Roles of diverse lipokines in metabolic homeostasis and their associations with various diseases. Comp. Physiol., 15, e70072 (2025); DOI.
Liu, J.F. and others. DGKs in lipid signaling and disease intervention: structural basis, pathological mechanisms, and emerging therapeutic strategies. Cell. Mol. Biol. Letts, 30, 129 (2025); DOI.
Mendes, A.C., Azevedo, G.M., Barcellos, A.P. and Bahia, D. Phosphatidylinositol 4-kinase as a target of pathogens-friend or foe? FEBS Letts, in press (2025); DOI.
Mondal, S., Kumar, S. and Sankaranarayanan, R. An integrative view on multiple lipid divide events as hallmarks of distinct evolutionary transitions. Biochemistry, 64, 4487-4497 (2025); DOI.
Nani, M.F., Rinaldi, M.M., Miraglia, M., Amico, R., De Cicco, P. and Romano, B. N-Acylethanolamines in cancer: mechanisms and therapeutic potential of lipid regulators of tumor behavior. Prog. Lipid Res., 100, 101358 (2025); DOI.
Roggero, A., Toyama, M.H. and Sousa, S.F. Lands' cycle at the crossroads: phospholipid remodelling, oxidative stress, cellular toxicity, and therapeutic targeting. ACS Pharm. Transl. Sci., 8, 3729-3756 (2025); DOI.
Rubino, R., Squillero, G., Prever, L., Fantastico, E., De Santis, M.C., Kahnamouei, A., Gulluni, F. and Hirsch, E. Decoding class II PI3K signaling: From membrane identity to human disease. Biochim. Biophys. Acta, Lipids, 1871, 159693 (2026); DOI.
Straub, V.M. and others. The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles. Proc. Natl. Acad. Sci. USA, 122, e2421717122 (2025); DOI.
Sun, L.H., Wang, J.Y. and Zhang, L.L. The role of sphingomyelin synthase 2 in lipid metabolism and its implications in diseases. Cell Biol. Int., in press (2025); DOI.
Teder, T., Rådmark, O., Haeggström, JZ. and Lohelaid, H. Animal models in leukotriene research: Current insights into complex pathways and therapeutic intervention. Pharmacol. Therapeut., 276, 108944 (2025); DOI.
Trivedi, P. and others. Scratching the surface: The diversity and roles of triterpenoids in plant cuticular waxes. Phytochem. Rev., in press (2025); DOI.
Tyagi, M., Paul, P.K. and Rameshwari, R. Ergosterol regulation of plant physiology; an underlooked perspective. Bot. Rev., in press (2025); DOI.
Wang, Y.C. and others. Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review). Int. J. Mol. Med., 57, 20 (2026); DOI.
Warren, W., Osborn, M., Yates, A. and O'Sullivan, S. The emerging role of fatty acid-binding protein 3 (FABP3) in cancer. Drug Discovery Today, 30, 104504 (2025); DOI.
Xu, M.K. and Xu, B. Protein lipidation in the tumor microenvironment: enzymology, signaling pathways, and therapeutics. Mol. Cancer, 24, 138 (2025); DOI.
Zhao, X.H. and Pandey, M.K. Central roles of glucosylceramide in driving cancer pathogenesis. Int. J. Mol. Sci., 26, 9879 (2025); DOI.

© Data compiled by Bill Christie
Updated: December 2025	Contact/credits/disclaimer