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LMPD Database

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LMP002716

Gene Information

Entrez Gene ID	20597
Gene Name	sphingomyelin phosphodiesterase 1, acid lysosomal
Gene Symbol	Smpd1
Species	Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005615	IEA:Ensembl	C	extracellular space
GO:0070062	IEA:Ensembl	C	extracellular vesicular exosome
GO:0042599	IEA:Ensembl	C	lamellar body
GO:0005764	IEA:UniProtKB-KW	C	lysosome
GO:0016798	IEA:UniProtKB-KW	F	hydrolase activity, acting on glycosyl bonds
GO:0004767	IEA:UniProtKB-EC	F	sphingomyelin phosphodiesterase activity
GO:0046513	IEA:Ensembl	P	ceramide biosynthetic process
GO:0043407	IEA:Ensembl	P	negative regulation of MAP kinase activity
GO:0043065	IEA:Ensembl	P	positive regulation of apoptotic process
GO:0035307	IEA:Ensembl	P	positive regulation of protein dephosphorylation
GO:0042220	IEA:Ensembl	P	response to cocaine
GO:0042493	IEA:Ensembl	P	response to drug
GO:0006685	IEA:InterPro	P	sphingomyelin catabolic process
GO:0023021	IEA:Ensembl	P	termination of signal transduction

KEGG Pathway Links

KEGG Pathway ID	Description
mmu04142	Lysosome
mmu00600	Sphingolipid metabolism

BIOCYC Pathway Links

BIOCYC Pathway ID	Description
PWY3DJ-11281	sphingomyelin metabolism

REACTOME Pathway Links

REACTOME Pathway ID	Description
5893995	Glycosphingolipid metabolism