LIPID MAPS® Structure Database (LMSD)
The LIPID MAPS® Structure Database (LMSD) is a relational database encompassing structures and annotations of biologically relevant lipids. As of today, LMSD contains 47867 unique lipid structures, making it the largest public lipid-only database in the world.
Structures of lipids in the database come from several sources: (i) LIPID MAPS® Consortium's core laboratories and partners; (ii) lipids identified by LIPID MAPS® experiments; (iii) biologically relevant lipids manually curated from LIPID BANK, LIPIDAT, Lipid Library, Cyberlipids, ChEBI and other public sources; (iv) novel lipids submitted to peer-reviewed journals; (v) computationally generated structures for appropriate classes.
All the lipid structures in LMSD adhere to the structure drawing rules proposed by the LIPID MAPS® consortium. All lipids in the LMSD have been classified using the LIPID MAPS® Lipid Classification System. Each lipid structure has been assigned a LIPID MAPS® ID (LM_ID) which reflects its position in the classification hierarchy. In addition to a classification-based retrieval of lipids, users can search LMSD using either text-based or structure-based search options.
| Lipid Category | Curated | Computationally-generated | All |
|---|---|---|---|
| Fatty Acyls [FA] | 8675 | 1878 | 10553 |
| Glycerolipids [GL] | 354 | 7379 | 7733 |
| Glycerophospholipids [GP] | 1746 | 8328 | 10074 |
| Sphingolipids [SP] | 1801 | 3168 | 4969 |
| Sterol Lipids [ST] | 3643 | 0 | 3643 |
| Prenol Lipids [PR] | 2401 | 0 | 2401 |
| Saccharolipids [SL] | 51 | 1294 | 1345 |
| Polyketides [PK] | 7149 | 0 | 7149 |
| TOTAL | 25820 | 22047 | 47867 |
Interfaces
We provide multiple options for accessing LMSD records, as outlined below.
- LIPID MAPS® Classification System — View lipids by category, or drill down to view lipids by main class, sub class.
- Keyword / ontology — Search by LM ID, name, mass, formula, category, main class, and subclass.
- Structure — Draw and search by complete structure or substructure in conjunction with optional data fields.
- Programmatic Access — Retrieve LMSD data via the command line using wget.
- Download — Download LMSD as an SDF file.
- Submit structures — Submit novel lipid structures and annotations for addition to LMSD.