LIPID MAPS® Structure Database (LMSD)

The LIPID MAPS® Structure Database (LMSD) is a relational database encompassing structures and annotations of biologically relevant lipids. As of today, LMSD contains 47704 unique lipid structures, making it the largest public lipid-only database in the world.

Structures of lipids in the database come from several sources: (i) LIPID MAPS® Consortium's core laboratories and partners; (ii) lipids identified by LIPID MAPS® experiments; (iii) biologically relevant lipids manually curated from LIPID BANK, LIPIDAT, Lipid Library, Cyberlipids, ChEBI and other public sources; (iv) novel lipids submitted to peer-reviewed journals; (v) computationally generated structures for appropriate classes.

All the lipid structures in LMSD adhere to the structure drawing rules proposed by the LIPID MAPS® consortium. All lipids in the LMSD have been classified using the LIPID MAPS® Lipid Classification System. Each lipid structure has been assigned a LIPID MAPS® ID (LM_ID) which reflects its position in the classification hierarchy. In addition to a classification-based retrieval of lipids, users can search LMSD using either text-based or structure-based search options.

Lipid Category Curated Computationally-generated All
Fatty Acyls [FA] 8634 1875 10509
Glycerolipids [GL] 352 7379 7731
Glycerophospholipids [GP] 1737 8327 10064
Sphingolipids [SP] 1793 3168 4961
Sterol Lipids [ST] 3571 0 3571
Prenol Lipids [PR] 2377 0 2377
Saccharolipids [SL] 51 1294 1345
Polyketides [PK] 7146 0 7146
TOTAL 25661 22043 47704
Number of structures per lipid category

Interfaces

We provide multiple options for accessing LMSD records, as outlined below.

References

Sud M, Fahy E, Cotter D, Brown A, Dennis EA, Glass CK, Merrill AH Jr, Murphy RC, Raetz CR, Russell DW, Subramaniam S., LMSD: LIPID MAPS® structure database Nucleic Acids Research, 35: p. D527-32., DOI: 10.1093/nar/gkl838 , PMID: 17098933
Fahy E, Sud M, Cotter D & Subramaniam S., LIPID MAPS® online tools for lipid research Nucleic Acids Research (2007), 35: p. W606-12., DOI: 10.1093/nar/gkm324 , PMID: 17584797