LIPID MAPS® Structure Database (LMSD)

The LIPID MAPS® Structure Database (LMSD) is a relational database encompassing structures and annotations of biologically relevant lipids. As of today, LMSD contains 46834 unique lipid structures, making it the largest public lipid-only database in the world.

Structures of lipids in the database come from several sources: (i) LIPID MAPS® Consortium's core laboratories and partners; (ii) lipids identified by LIPID MAPS® experiments; (iii) biologically relevant lipids manually curated from LIPID BANK, LIPIDAT, Lipid Library, Cyberlipids, ChEBI and other public sources; (iv) novel lipids submitted to peer-reviewed journals; (v) computationally generated structures for appropriate classes.

All the lipid structures in LMSD adhere to the structure drawing rules proposed by the LIPID MAPS® consortium. All lipids in the LMSD have been classified using the LIPID MAPS® Lipid Classification System. Each lipid structure has been assigned a LIPID MAPS® ID (LM_ID) which reflects its position in the classification hierarchy. In addition to a classification-based retrieval of lipids, users can search LMSD using either text-based or structure-based search options.

Lipid Category Curated Computationally-generated All
Fatty Acyls [FA] 8505 1875 10380
Glycerolipids [GL] 326 7379 7705
Glycerophospholipids [GP] 1725 8312 10037
Sphingolipids [SP] 1784 3168 4952
Sterol Lipids [ST] 3297 0 3297
Prenol Lipids [PR] 2026 0 2026
Saccharolipids [SL] 41 1294 1335
Polyketides [PK] 7102 0 7102
TOTAL 24806 22028 46834
Number of structures per lipid category

Interfaces

We provide multiple options for accessing LMSD records, as outlined below.

References

Sud M, Fahy E, Cotter D, Brown A, Dennis EA, Glass CK, Merrill AH Jr, Murphy RC, Raetz CR, Russell DW, Subramaniam S., LMSD: LIPID MAPS® structure database Nucleic Acids Research, 35: p. D527-32., DOI: 10.1093/nar/gkl838 , PMID: 17098933
Fahy E, Sud M, Cotter D & Subramaniam S., LIPID MAPS® online tools for lipid research Nucleic Acids Research (2007), 35: p. W606-12., DOI: 10.1093/nar/gkm324 , PMID: 17584797