LMPD Database

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LMP001389

UniProt Annotations

Entry Information
Gene Nameglycosylphosphatidylinositol anchor attachment 1
Protein EntryGPAA1_HUMAN
UniProt IDO43292
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=O43292-1; Sequence=Displayed; Name=2; IsoId=O43292-2; Sequence=VSP_009542;
FunctionEssential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate.
PathwayGlycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Sequence CautionSequence=CAB75660.2; Type=Erroneous gene model prediction; Note=Erroneous prediction from an unspliced cDNA.; Evidence= ;
Subcellular LocationEndoplasmic reticulum membrane ; Multi-pass membrane protein .
SubunitForms a complex with PIGK/GPI8, PIGT, PIGU and PIGS.
Tissue SpecificityUbiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues.