LMPD Database

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LMP001389

Record overview

LMPD IDLMP001389
Gene ID8733
SpeciesHomo sapiens (Human)
Gene Nameglycosylphosphatidylinositol anchor attachment 1
Gene SymbolGPAA1
SynonymsGAA1; hGAA1
Alternate namesglycosylphosphatidylinositol anchor attachment 1 protein; GAA1 protein homolog; GPI transamidase subunit; GPI anchor attachment protein 1; GPAA1P anchor attachment protein 1 homolog; glycophosphatidylinositol anchor attachment 1; anchor attachment protein 1 (Gaa1p, yeast) homolog; glycosylphosphatidylinositol anchor attachment protein 1 homolog
Chromosome8
Map Location8q24.3
SummaryPosttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for GPAA1

Proteins

glycosylphosphatidylinositol anchor attachment 1 protein
Refseq ID:NP_003792
Protein GI:4504079
UniProt ID:O43292
mRNA ID:NM_003801
Length:621
RefSeq Status:REVIEWED
MGLLSDPVRRRALARLVLRLNAPLCVLSYVAGIAWFLALVFPPLTQRTYMSENAMGSTMVEEQFAGGDRARAFARDFAAHRKKSGALPVAWLERTMRSVG
LEVYTQSFSRKLPFPDETHERYMVSGTNVYGILRAPRAASTESLVLTVPCGSDSTNSQAVGLLLALAAHFRGQIYWAKDIVFLVTEHDLLGTEAWLEAYH
DVNVTGMQSSPLQGRAGAIQAAVALELSSDVVTSLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPEDWTSLDGPLQGLQTLLLMVLRQASG
RPHGSHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFLYLLPGLSRFVSIGLYMPAVGFLLLVLGLKALELWMQLHEAG
MGLEEPGGAPGPSVPLPPSQGVGLASLVAPLLISQAMGLALYVLPVLGQHVATQHFPVAEAEAVVLTLLAIYAAGLALPHNTHRVVSTQAPDRGWMALKL
VALIYLALQLGCIALTNFSLGFLLATTMVPTAALAKPHGPRTLYAALLVLTSPAATLLGSLFLWRELQEAPLSLAEGWQLFLAALAQGVLEHHTYGALLF
PLLSLGLYPCWLLFWNVLFWK