LMPD Database

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LMP012460

UniProt Annotations

Entry Information

Gene Name	polymeric immunoglobulin receptor
Protein Entry	PIGR_RAT
UniProt ID	P15083
Species	Rat

Comments

Comment type	Description
Function	This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Similarity	Contains 5 Ig-like V-type (immunoglobulin-like) domains
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Subcellular Location	Secretory component: Secreted.