LMPD Database

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LMP010752

Record overview

LMPD IDLMP010752
Gene ID821718
SpeciesArabidopsis thaliana (Arabidopsis)
Gene Nameputative peptidyl-prolyl cis-trans isomerase FKBP42
Gene SymbolTWD1
SynonymsATFKBP42; FK506-BINDING PROTEIN 42; FKBP42; TWD1; TWISTED DWARF 1; UCU2; ULTRACURVATA 2
Alternate namesputative peptidyl-prolyl cis-trans isomerase FKBP42
Chromosome3
EC Number5.2.1.8
Summaryencodes a 42 kDa FK506-binding protein (AtFKBP42) that possesses similarity to multidomain peptidyl-prolyl cis/trans isomerases (PPIases, EC 5.2.1.8), which are known to be components of mammalian steroid hormone receptor complexes. The protein appears to be localized to the plasma membrane by electron microscopy and binds to HSP90.1 and calmodulin in vitro. It also aggregates citrate synthase in vitro but does NOT show PPIase activity in vivo. Mutants are reduced in size and exhibit disoriented growth in all organs.
OrthologsView orthologs and multiple alignments for TWD1

Proteins

putative peptidyl-prolyl cis-trans isomerase FKBP42
Refseq ID:NP_188801
Protein GI:30686321
UniProt ID:Q9LDC0
mRNA ID:NM_113059
Length:365
RefSeq Status:REVIEWED
MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLG
KEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQ
QYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAI
RRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKSLFWLIVLWQWFVSLFSRIFRRHRVKAD