LMPD Database

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LMP009869

UniProt Annotations

Entry Information
Gene Nameaquaporin TIP1-1
Protein EntryTIP11_ARATH
UniProt IDP25818
SpeciesArabidopsis
Comments
Comment typeDescription
Disruption PhenotypePlants display lesion formation or plant death, and low contents of glucose, fructose, inositol, and threonic, succinic, fumaric, and malic acids. {ECO:0000269|PubMed:15584951}.
DomainAquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
FunctionWater channel required to facilitate the transport of water, diffusion of amino acids and/or peptides from the vacuolar compartment to the cytoplasm. Does not promote glycerol permeability. May play a role in the control of cell turgor and cell expansion. Its function is impaired by Hg(2+). May be involved in a vesicle-based metabolite routing through or between pre-vacuolar compartments and the central vacuole. Transports urea in yeast cells in a pH-independent manner. Transports H(2)O(2) in yeast cells. {ECO:0000269|PubMed:14576283, ECO:0000269|PubMed:15584951, ECO:0000269|PubMed:17105724, ECO:0000269|PubMed:8508761}.
InductionBy gibberellins.
Sequence CautionSequence=CAA38633.1; Type=Frameshift; Positions=244; Evidence={ECO:0000305};
SimilarityBelongs to the MIP/aquaporin (TC 1.A.8) family. TIP (TC 1.A.8.10) subfamily. {ECO:0000305}.
Subcellular LocationVacuole membrane {ECO:0000269|PubMed:15584951}; Multi-pass membrane protein {ECO:0000269|PubMed:15584951}. Note=Tonoplast. Specifically located in the tonoplast of lytic or degradative vacuoles (LV) (By similarity). {ECO:0000250}.
SubunitInteracts with cucumber mosaic virus (CMV) Protein 1a. {ECO:0000269|PubMed:17030879}.
Tissue SpecificityIn all the vegetative organs, but not in seeds. Preferentially expressed in roots. {ECO:0000269|PubMed:8624437}.