LMPD Database

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LMP008179

UniProt Annotations

Entry Information
Gene NameProtein FUM-1
Protein EntryQ8ITZ0_CAEEL
UniProt IDQ8ITZ0
SpeciesC. elegans
Comments
Comment typeDescription
Catalytic Activity(S)-malate = fumarate + H(2)O.
MiscellaneousThere are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors (By similarity). {ECO:0000250}.
PathwayCarbohydrate metabolism; tricarboxylic acid cycle; (S)- malate from fumarate: step 1/1.
SimilarityBelongs to the class-II fumarase/aspartase family. Fumarase subfamily. {ECO:0000305}.
Subcellular LocationMitochondrion {ECO:0000250}.