LMPD Database

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LMP006684

Record overview

LMPD IDLMP006684
Gene ID26007
SpeciesHomo sapiens (Human)
Gene Namedihydroxyacetone kinase 2 homolog (S. cerevisiae)
Gene SymbolDAK
SynonymsNET45
Alternate namesbifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); DHA kinase; glycerone kinase; Dha kinase/FMN cyclase; FAD-AMP lyase cyclizing; FAD-AMP lyase cyclic FMN forming; ATP-dependent dihydroxyacetone kinase
Chromosome11
Map Location11q12.2
EC Number2.7.1.28
SummaryThis gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4',5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been identified, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for DAK

Proteins

bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)
Refseq ID:NP_056348
Protein GI:20149621
UniProt ID:Q3LXA3
mRNA ID:NM_015533
Length:575
RefSeq Status:REVIEWED
MTSKKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDSLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVAQAG
TVGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVIGDDSAFTVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEEIAKQVNVVAKAMGTLGVSLSSCSV
PGSKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKLMLDHMTNTTNASHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALV
GTFMSALEMPGISLTLLLVDEPLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEAPDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAG
DGDCGTTHSRAARAIQEWLKEGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLPAWSAAMDAGLEAMQKYGKAAPGDRTMLDSLW
AAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAGAGRASYISSARLEQPDPGAVAAAAILRAILEVLQS