LMPD Database

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LMP004249

Gene Information

Entrez Gene ID12759
Gene Nameclusterin
Gene SymbolClu
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0097440 ISS:Alzheimers_University_of_TorontoCapical dendrite
GO:0072562 IEA:EnsemblCblood microparticle
GO:0005737 ISS:Alzheimers_University_of_TorontoCcytoplasm
GO:0031410 IEA:UniProtKB-KWCcytoplasmic vesicle
GO:0005783 IEA:UniProtKB-KWCendoplasmic reticulum
GO:0031012 IEA:EnsemblCextracellular matrix
GO:0005615 ISS:UniProtKBCextracellular space
GO:0070062 IEA:EnsemblCextracellular vesicular exosome
GO:0016020 IEA:UniProtKB-KWCmembrane
GO:0005739 IEA:UniProtKB-KWCmitochondrion
GO:0097418 ISS:Alzheimers_University_of_TorontoCneurofibrillary tangle
GO:0005634 IEA:UniProtKB-KWCnucleus
GO:0048471 ISS:UniProtKBCperinuclear region of cytoplasm
GO:0034366 ISS:UniProtKBCspherical high-density lipoprotein particle
GO:0051787 ISS:UniProtKBFmisfolded protein binding
GO:0031625 ISS:UniProtKBFubiquitin protein ligase binding
GO:0000902 ISS:Alzheimers_University_of_TorontoPcell morphogenesis
GO:0032286 ISS:Alzheimers_University_of_TorontoPcentral nervous system myelin maintenance
GO:0051131 ISS:Alzheimers_University_of_TorontoPchaperone-mediated protein complex assembly
GO:0061077 ISS:UniProtKBPchaperone-mediated protein folding
GO:0097193 ISS:UniProtKBPintrinsic apoptotic signaling pathway
GO:0001774 ISS:Alzheimers_University_of_TorontoPmicroglial cell activation
GO:0061518 ISS:Alzheimers_University_of_TorontoPmicroglial cell proliferation
GO:1902430 ISS:Alzheimers_University_of_TorontoPnegative regulation of beta-amyloid formation
GO:1902230 ISS:BHF-UCLPnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0032463 ISS:UniProtKBPnegative regulation of protein homooligomerization
GO:0043065 ISS:UniProtKBPpositive regulation of apoptotic process
GO:1902004 IMP:Alzheimers_University_of_TorontoPpositive regulation of beta-amyloid formation
GO:2001244 ISS:UniProtKBPpositive regulation of intrinsic apoptotic signaling pathway
GO:1902998 ISS:Alzheimers_University_of_TorontoPpositive regulation of neurofibrillary tangle assembly
GO:1901216 IMP:Alzheimers_University_of_TorontoPpositive regulation of neuron death
GO:0051092 ISS:UniProtKBPpositive regulation of NF-kappaB transcription factor activity
GO:0045429 ISS:Alzheimers_University_of_TorontoPpositive regulation of nitric oxide biosynthetic process
GO:0032436 ISS:UniProtKBPpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:2000060 ISS:UniProtKBPpositive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:1902949 ISS:Alzheimers_University_of_TorontoPpositive regulation of tau-protein kinase activity
GO:0032760 ISS:Alzheimers_University_of_TorontoPpositive regulation of tumor necrosis factor production
GO:0017038 ISS:Alzheimers_University_of_TorontoPprotein import
GO:0050821 ISS:UniProtKBPprotein stabilization
GO:1900221 ISS:Alzheimers_University_of_TorontoPregulation of beta-amyloid clearance
GO:1902847 ISS:Alzheimers_University_of_TorontoPregulation of neuronal signal transduction
GO:1901214 ISS:Alzheimers_University_of_TorontoPregulation of neuron death
GO:0051788 ISS:UniProtKBPresponse to misfolded protein
GO:0009615 IEA:EnsemblPresponse to virus
REACTOME Pathway Links
REACTOME Pathway IDDescription
5893155Hemostasis
5893154Platelet activation, signaling and aggregation
5893613Platelet degranulation
5893156Response to elevated platelet cytosolic Ca2+