LMPD Database

LMP003356

Gene Information

Entrez Gene ID	14775
Gene Name	glutathione peroxidase 1
Gene Symbol	Gpx1
Species	Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	ISS:BHF-UCL	C	cytoplasm
GO:0070062	IEA:Ensembl	C	extracellular vesicular exosome
GO:0005739	IDA:MGI	C	mitochondrion
GO:0005634	IEA:Ensembl	C	nucleus
GO:0043295	IEA:Ensembl	F	glutathione binding
GO:0004602	IDA:MGI	F	glutathione peroxidase activity
GO:0047066	IEA:Ensembl	F	phospholipid-hydroperoxide glutathione peroxidase activity
GO:0008430	IEA:Ensembl	F	selenium binding
GO:0007568	IEA:Ensembl	P	aging
GO:0060055	IMP:MGI	P	angiogenesis involved in wound healing
GO:0006915	IMP:MGI	P	apoptotic process
GO:0043534	IMP:MGI	P	blood vessel endothelial cell migration
GO:0008283	IMP:MGI	P	cell proliferation
GO:0045454	IEA:Ensembl	P	cell redox homeostasis
GO:0001885	IMP:MGI	P	endothelial cell development
GO:0045444	IMP:MGI	P	fat cell differentiation
GO:0006749	IEA:Ensembl	P	glutathione metabolic process
GO:0060047	IMP:MGI	P	heart contraction
GO:0042744	IMP:MGI	P	hydrogen peroxide catabolic process
GO:0051702	IGI:MGI	P	interaction with symbiont
GO:0008631	IMP:MGI	P	intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0006629	IMP:MGI	P	lipid metabolic process
GO:0051450	IMP:MGI	P	myoblast proliferation
GO:0014902	IMP:MGI	P	myotube differentiation
GO:0043066	IMP:MGI	P	negative regulation of apoptotic process
GO:0043154	IEA:Ensembl	P	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:1902042	IEA:Ensembl	P	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0002862	IGI:MGI	P	negative regulation of inflammatory response to antigenic stimulus
GO:1902176	IMP:MGI	P	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0090201	IEA:Ensembl	P	negative regulation of release of cytochrome c from mitochondria
GO:0051897	IMP:MGI	P	positive regulation of protein kinase B signaling
GO:0018158	IMP:MGI	P	protein oxidation
GO:0040029	IEA:Ensembl	P	regulation of gene expression, epigenetic
GO:0033599	IEA:Ensembl	P	regulation of mammary gland epithelial cell proliferation
GO:0043523	IMP:MGI	P	regulation of neuron apoptotic process
GO:0061136	IEA:Ensembl	P	regulation of proteasomal protein catabolic process
GO:0032355	IEA:Ensembl	P	response to estradiol
GO:0051593	IEA:Ensembl	P	response to folic acid
GO:0010332	IGI:MGI	P	response to gamma radiation
GO:0009749	IEA:Ensembl	P	response to glucose
GO:0042542	ISS:BHF-UCL	P	response to hydrogen peroxide
GO:0033194	IMP:MGI	P	response to hydroperoxide
GO:0006982	IEA:Ensembl	P	response to lipid hydroperoxide
GO:0035094	IEA:Ensembl	P	response to nicotine
GO:0006979	IMP:MGI	P	response to oxidative stress
GO:0000302	IMP:MGI	P	response to reactive oxygen species
GO:0010269	IEA:Ensembl	P	response to selenium ion
GO:0009609	IGI:MGI	P	response to symbiotic bacterium
GO:0009636	IMP:MGI	P	response to toxic substance
GO:0009611	IMP:MGI	P	response to wounding
GO:0009410	IMP:MGI	P	response to xenobiotic stimulus
GO:0007605	IMP:MGI	P	sensory perception of sound
GO:0048741	IMP:MGI	P	skeletal muscle fiber development
GO:0043403	IMP:MGI	P	skeletal muscle tissue regeneration
GO:0001659	IGI:MGI	P	temperature homeostasis
GO:0006641	IMP:MGI	P	triglyceride metabolic process
GO:0009650	IEA:Ensembl	P	UV protection
GO:0042311	IMP:MGI	P	vasodilation

KEGG Pathway Links

KEGG Pathway ID	Description
mmu04918	Thyroid hormone synthesis