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LMP003356

Record overview

LMPD IDLMP003356
Gene ID14775
SpeciesMus musculus(Mouse)
Gene Nameglutathione peroxidase 1
Gene SymbolGpx1
SynonymsAI195024; AL033363; CGPx; GPx-1; GSHPx-1; Gpx
Alternate namesglutathione peroxidase 1; cellular glutathione peroxidase; selenium-dependent glutathione peroxidase 1
Chromosome9
Map Location9 F1|9 59.24 cM
EC Number1.11.1.9
SummaryThis gene product belongs to the family of glutathione peroxidase, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for Gpx1

Proteins

glutathione peroxidase 1
Refseq ID:NP_032186
Protein GI:84871986
UniProt ID:P11352
mRNA ID:NM_008160
Length:201
RefSeq Status:REVIEWED
MCAARLSAAAQSTVYAFSARPLTGGEPVSLGSLRGKVLLIENVASLUGTTIRDYTEMNDLQKRLGPRGLVVLGFPCNQFGHQENGKNEEILNSLKYVRPG
GGFEPNFTLFEKCEVNGEKAHPLFTFLRNALPTPSDDPTALMTDPKYIIWSPVCRNDIAWNFEKFLVGPDGVPVRRYSRRFRTIDIEPDIETLLSQQSGN
S