LMPD Database

LMP002758

Record overview

LMPD ID	LMP002758
Gene ID	2583
Species	Homo sapiens (Human)
Gene Name	beta-1,4-N-acetyl-galactosaminyl transferase 1
Gene Symbol	B4GALNT1
Synonyms	GALGT; GALNACT; GalNAc-T; SPG26
Chromosome	12
Map Location	12q13.3
EC Number	2.4.1.92
Summary	GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
Orthologs	View orthologs and multiple alignments for B4GALNT1

Proteins

beta-1,4 N-acetylgalactosaminyltransferase 1 isoform 1 precursor

Refseq ID:	NP_001469
Protein GI:	4503893
UniProt ID:	Q00973
mRNA ID:	NM_001478
Length:	533
RefSeq Status:	REVIEWED

MWLGRRALCALVLLLACASLGLLYASTRDAPGLRLPLAPWAPPQSPRRPELPDLAPEPRYAHIPVRIKEQVVGLLAWNNCSCESSGGGLPLPFQKQVRAI
DLTKAFDPAELRAASATREQEFQAFLSRSQSPADQLLIAPANSPLQYPLQGVEVQPLRSILVPGLSLQAASGQEVYQVNLTASLGTWDVAGEVTGVTLTG
EGQADLTLVSPGLDQLNRQLQLVTYSSRSYQTNTADTVRFSTEGHEAAFTIRIRHPPNPRLYPPGSLPQGAQYNISALVTIATKTFLRYDRLRALITSIR
RFYPTVTVVIADDSDKPERVSGPYVEHYLMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFVFTARTRLERLVDVLERTPLDLVGGAVREISGFATTYRQLL
SVEPGAPGLGNCLRQRRGFHHELVGFPGCVVTDGVVNFFLARTDKVREVGFDPRLSRVAHLEFFLDGLGSLRVGSCSDVVVDHASKLKLPWTSRDAGAET
YARYRYPGSLDESQMAKHRLLFFKHRLQCMTSQ

sig_peptide: 1..25
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2691
peptide sequence: 
MWLGRRALCALVLLLACASLGLLYA

sig_peptide: 1..25
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2691
peptide sequence: 
MWLGRRALCALVLLLACASLGLLYA

sig_peptide: 1..25
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2691
peptide sequence: 
MWLGRRALCALVLLLACASLGLLYA

beta-1,4 N-acetylgalactosaminyltransferase 1 isoform 2 precursor

Refseq ID:	NP_001263397
Protein GI:	451172101
UniProt ID:	Q00973
mRNA ID:	NM_001276468
Length:	478
RefSeq Status:	REVIEWED

MWLGRRALCALVLLLACASLGLLYASTRDAPGLRLPLAPWAPPQSPRRPELPDLAPEPRYAHIPVRIKEQVVGSQSPADQLLIAPANSPLQYPLQGVEVQ
PLRSILVPGLSLQAASGQEVYQVNLTASLGTWDVAGEVTGVTLTGEGQADLTLVSPGLDQLNRQLQLVTYSSRSYQTNTADTVRFSTEGHEAAFTIRIRH
PPNPRLYPPGSLPQGAQYNISALVTIATKTFLRYDRLRALITSIRRFYPTVTVVIADDSDKPERVSGPYVEHYLMPFGKGWFAGRNLAVSQVTTKYVLWV
DDDFVFTARTRLERLVDVLERTPLDLVGGAVREISGFATTYRQLLSVEPGAPGLGNCLRQRRGFHHELVGFPGCVVTDGVVNFFLARTDKVREVGFDPRL
SRVAHLEFFLDGLGSLRVGSCSDVVVDHASKLKLPWTSRDAGAETYARYRYPGSLDESQMAKHRLLFFKHRLQCMTSQ

beta-1,4 N-acetylgalactosaminyltransferase 1 isoform 3 precursor

Refseq ID:	NP_001263398
Protein GI:	451172103
UniProt ID:	Q00973
mRNA ID:	NM_001276469
Length:	328
RefSeq Status:	REVIEWED

`MWLGRRALCALVLLLACASLGLLYASTRDAPGLRLPLAPWAPPQSPRRPELPDLAPEPRYAHIPVRIKEQVVGLLAWNNCSCESSGGGLPLPFQKQVRAI DLTKAFDPAELRAASATREQEFQAFLSRSQSPADQLLIAPANSPLQYPLQGVEVQPLRSILVPGLSLQAASGQEVYQVNLTASLGTWDVAGEVTGVTLTG EGQADLTLVSPGLDQLNRQLQLVTYSSRSYQTNTADTGARPGWRDGQAGQTEKNQKGWSGQMAEGMGGIWAMARAVQPHNGCFNWTSRARGRKGAFVHLG LEQARGKPEPWVCLPFRPTVGGPRKRLV`