LMPD Database

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LMP002590

Gene Information

Entrez Gene ID65112
Gene Nameprostate transmembrane protein, androgen induced 1
Gene SymbolPmepa1
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031901 ISS:UniProtKBCearly endosome membrane
GO:0010008 ISS:UniProtKBCendosome membrane
GO:0000139 ISS:UniProtKBCGolgi membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0060394 IDA:UniProtKBPnegative regulation of pathway-restricted SMAD protein phosphorylation
GO:0010991 ISS:UniProtKBPnegative regulation of SMAD protein complex assembly
GO:0030512 IDA:UniProtKBPnegative regulation of transforming growth factor beta receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
5892763Disease
5893348Downregulation of TGF-beta receptor signaling
5893328Loss of Function of SMAD2/3 in Cancer
5893331Loss of Function of SMAD4 in Cancer
5893337Loss of Function of TGFBR1 in Cancer
5893334Loss of Function of TGFBR2 in Cancer
5893326Signaling by TGF-beta Receptor Complex
5893329Signaling by TGF-beta Receptor Complex in Cancer
5892891Signal Transduction
5893332SMAD2/3 MH2 Domain Mutants in Cancer
5893327SMAD2/3 Phosphorylation Motif Mutants in Cancer
5893330SMAD4 MH2 Domain Mutants in Cancer
5893325TGF-beta receptor signaling activates SMADs
5893336TGFBR1 KD Mutants in Cancer
5893338TGFBR1 LBD Mutants in Cancer
5893335TGFBR2 Kinase Domain Mutants in Cancer
5893333TGFBR2 MSI Frameshift Mutants in Cancer