LMPD Database

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LMP002003

Gene Information

Entrez Gene ID5739
Gene Nameprostaglandin I2 (prostacyclin) receptor (IP)
Gene SymbolPTGIR
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IDA:BHF-UCLCcytosol
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005886 IDA:BHF-UCLCplasma membrane
GO:0004930 IEA:UniProtKB-KWFG-protein coupled receptor activity
GO:0005085 TAS:ReactomeFguanyl-nucleotide exchange factor activity
GO:0007189 IMP:BHF-UCLPadenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007596 TAS:ReactomePblood coagulation
GO:0007267 TAS:ProtIncPcell-cell signaling
GO:0007187 TAS:ProtIncPG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0010642 ISS:BHF-UCLPnegative regulation of platelet-derived growth factor receptor signaling pathway
GO:0048662 IDA:BHF-UCLPnegative regulation of smooth muscle cell proliferation
GO:0030819 IMP:BHF-UCLPpositive regulation of cAMP biosynthetic process
GO:0043950 IMP:BHF-UCLPpositive regulation of cAMP-mediated signaling
GO:0043547 TAS:GOCPpositive regulation of GTPase activity
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04611Platelet activation
hsa04270Vascular smooth muscle contraction