LMPD Database

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LMP001732

Record overview

LMPD IDLMP001732
Gene ID9588
SpeciesHomo sapiens (Human)
Gene Nameperoxiredoxin 6
Gene SymbolPRDX6
Synonyms1-Cys; AOP2; HEL-S-128m; NSGPx; PRX; aiPLA2; p29
Alternate namesperoxiredoxin-6; 1-Cys PRX; 24 kDa protein; 1-Cys peroxiredoxin; antioxidant protein 2; liver 2D page spot 40; red blood cells page spot 12; non-selenium glutathione peroxidase; acidic calcium-independent phospholipase A2; epididymis secretory sperm binding protein Li 128m
Chromosome1
Map Location1q25.1
EC Number1.11.1.15
SummaryThe protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PRDX6

Proteins

peroxiredoxin-6
Refseq ID:NP_004896
Protein GI:4758638
UniProt ID:P30041
mRNA ID:NM_004905
Length:224
RefSeq Status:REVIEWED
MPGGLLLGDVAPNFEANTTVGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPF
PIIDDRNRELAILLGMLDPAEKDEKGMPVTARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDWKDGDSVMVLPTIPEEEAKK
LFPKGVFTKELPSGKKYLRYTPQP