LMPD Database

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LMP007562

Record overview

LMPD IDLMP007562
Gene ID944777
SpeciesEscherecia coli (E. coli)
Gene Name4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4Fe-4S protein
Gene SymBolispH
SynonymsECK0030; JW0027; lytB; yaaE
Summary1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (IspH) catalyzes what is effectively the final step in the methylerythritol phosphate pathway, generating the two pathway products isopentyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP). [More information is available at EcoCyc: EG11081].
OrthologsView orthologs and multiple alignments for ispH

Proteins

4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4Fe-4S protein [Escherichia coli str. K-12 substr. MG1655]
Refseq ID:NP_414570
Protein GI:16128023
UniProt ID:P62623
mRNA ID:
Length:316
RefSeq Status:REVIEWED
MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVT
KVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYAT
TNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENI
VFEVPKELRVDIREVD