August, 2016 update

New funding! - We are pleased to announce a new 5-year £1,362,256 Biomedical Resources Grant from the Wellcome Trust, awarded to Cardiff University, Babraham Institute and UCSD for the continuation of the LIPID MAPS infrastructure and the migration of the LIPID MAPS website to the UK over the next year. The LIPID MAPS international team of researchers will be led by Prof. Valerie O'Donnell, Prof. Shankar Subramaniam, Prof. Michael Wakelam, Prof. Edward Dennis, Dr Eoin Fahy, Dr Robert Andrews and Dr Simon Andrews. The Wellcome Trust is a global charitable foundation dedicated to improving health by supporting bright minds in science, the humanities and social sciences, and public engagement.


    • LIPID MAPS® Highlights

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    • Lipid of the month

      ceramide.png

      Chenodeoxycholic acid (3alpha,7alpha-dihydroxy-5ß-cholan-24-oic acid) is a C24 bile acid and one of the main bile acids produced by the liver. Chenodeoxycholic acid is synthesized in the liver from cholesterol and can be conjugated in the liver with taurine or glycine, forming taurochenodeoxycholic acid or glycochenodeoxycholic acid. Chenodeoxycholic acid is the most potent natural bile acid for stimulating the nuclear bile acid receptor, farnesoid X receptor. The transcription of many genes is activated by FXR.

Key LIPID MAPS® Resources
Publications
- publications related to projects funded through the LIPID MAPS® consortium
Lipid Classification System
- the first internationally accepted lipid classification system
Lipid Standards
- MS/MS spectra, annotations for principal product ions, and acquisition parameters
Experimental Data
- centralized studies on macrophages, lipidomics data on human plasma, and more
Structure Database (LMSD)
- over 40,000 unique structures of biologically relevant lipids
Proteome Database (LMPD)
- over 12,500 lipid-associated proteins from major research species
Pathways
- manually curated lipid metabolism and signaling pathways
LIPID MAPS® REST Service
- web-based/programmatic access to lipid structure and lipid-related gene/protein data
MS analysis tools
- tools for searching various lipid classes by precursor or product ion
Structure Drawing Tools
- draw and save lipid structures using online menus
Protocols
- LIPID MAPS® techniques for lipidomics and macrophage cell culture

LIPID MAPS® is funded by a grant from the Wellcome Trust.

logo LIPID MAPS® is funded by a grant from the Wellcome Trust.