July, 2016 update

New funding! - We are pleased to announce a new 5-year £1,362,256 Biomedical Resources Grant from the Wellcome Trust, awarded to Cardiff University, Babraham Institute and UCSD for the continuation of the LIPID MAPS infrastructure and the migration of the LIPID MAPS website to the UK over the next year. The LIPID MAPS international team of researchers will be led by Prof. Valerie O'Donnell, Prof. Shankar Subramaniam, Prof. Michael Wakelam, Prof. Edward Dennis, Dr Eoin Fahy, Dr Robert Andrews and Dr Simon Andrews. The Wellcome Trust is a global charitable foundation dedicated to improving health by supporting bright minds in science, the humanities and social sciences, and public engagement.

    • LIPID MAPS® Highlights

      more highlights

    • Lipid of the month


      Ceramides, such as Cer(d18:1/16:0) (systematic name: N-(hexadecanoyl)-sphing-4-enine) are a class of sphingolipids composed of the long-chain base sphingosine attached to a fatty acid via an N-acyl linkage. Ceramides are found in high concentrations within the cell membrane of cells. De novo synthesis of ceramide occurs in the endoplasmic reticulum. Ceramide is subsequently transported to the Golgi apparatus by either vesicular trafficking or the ceramide transfer protein CERT. Once in the Golgi apparatus, ceramide can be further metabolized to other sphingolipids, such as sphingomyelin (a key component of cell membranes) and the complex glycosphingolipids.

Key LIPID MAPS® Resources
- publications related to projects funded through the LIPID MAPS® consortium
Lipid Classification System
- the first internationally accepted lipid classification system
Lipid Standards
- MS/MS spectra, annotations for principal product ions, and acquisition parameters
Experimental Data
- centralized studies on macrophages, lipidomics data on human plasma, and more
Structure Database (LMSD)
- over 40,000 unique structures of biologically relevant lipids
Proteome Database (LMPD)
- over 12,500 lipid-associated proteins from major research species
- manually curated lipid metabolism and signaling pathways
- web-based/programmatic access to lipid structure and lipid-related gene/protein data
MS analysis tools
- tools for searching various lipid classes by precursor or product ion
Structure Drawing Tools
- draw and save lipid structures using online menus
- LIPID MAPS® techniques for lipidomics and macrophage cell culture

LIPID MAPS® is funded by a grant from the Wellcome Trust.

logo LIPID MAPS® is funded by a grant from the Wellcome Trust.