LMPD Database

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LMP006760

Record overview

LMPD IDLMP006760
Gene ID145482
SpeciesHomo sapiens (Human)
Gene Nameprostaglandin reductase 2
Gene SymbolPTGR2
SynonymsHEL-S-298; PGR2; ZADH1
Alternate namesprostaglandin reductase 2; PRG-2; 15-oxoprostaglandin 13-reductase; epididymis secretory protein Li 298; 15-oxoprostaglandin-delta13-reductase; zinc binding alcohol dehydrogenase, domain containing 1; zinc-binding alcohol dehydrogenase domain-containing protein 1
Chromosome14
Map Location14q24.3
EC Number1.3.1.48
SummaryThis gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
OrthologsView orthologs and multiple alignments for PTGR2

Proteins

prostaglandin reductase 2
Refseq ID:NP_001139626
Protein GI:226246680
UniProt ID:Q8N8N7
mRNA ID:NM_001146154
Length:351
RefSeq Status:REVIEWED
MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFY
WPWQTKVILDGNSLEKVDPQLVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSEL
GFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGI
LQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL
 
prostaglandin reductase 2
Refseq ID:NP_001139627
Protein GI:226246682
UniProt ID:Q8N8N7
mRNA ID:NM_001146155
Length:351
RefSeq Status:REVIEWED
Protein sequence is identical to GI:226246680 (mRNA isoform)
 
prostaglandin reductase 2
Refseq ID:NP_689657
Protein GI:22748929
UniProt ID:Q8N8N7
mRNA ID:NM_152444
Length:351
RefSeq Status:REVIEWED
Protein sequence is identical to GI:226246680 (mRNA isoform)