LMPD Database

LMP001272

Gene Information

Entrez Gene ID	3248
Gene Name	hydroxyprostaglandin dehydrogenase 15-(NAD)
Gene Symbol	HPGD
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0016323	IEA:Ensembl	C	basolateral plasma membrane
GO:0005829	NAS:UniProtKB	C	cytosol
GO:0070062	IDA:UniProt	C	extracellular vesicular exosome
GO:0016404	IDA:UniProtKB	F	15-hydroxyprostaglandin dehydrogenase (NAD+) activity
GO:0003824	IDA:UniProtKB	F	catalytic activity
GO:0051287	IDA:UniProtKB	F	NAD binding
GO:0070403	IDA:UniProtKB	F	NAD+ binding
GO:0004957	IDA:UniProtKB	F	prostaglandin E receptor activity
GO:0042803	TAS:UniProtKB	F	protein homodimerization activity
GO:0019369	TAS:Reactome	P	arachidonic acid metabolic process
GO:0019371	TAS:Reactome	P	cyclooxygenase pathway
GO:0097070	ISS:UniProtKB	P	ductus arteriosus closure
GO:0007565	IDA:UniProtKB	P	female pregnancy
GO:2001300	TAS:Reactome	P	lipoxin metabolic process
GO:0019372	TAS:UniProtKB	P	lipoxygenase pathway
GO:0045786	IDA:UniProtKB	P	negative regulation of cell cycle
GO:0030728	ISS:UniProtKB	P	ovulation
GO:0007567	IDA:UniProtKB	P	parturition
GO:0006693	IDA:UniProtKB	P	prostaglandin metabolic process
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0070493	ISS:UniProtKB	P	thrombin receptor signaling pathway
GO:0007179	IDA:UniProtKB	P	transforming growth factor beta receptor signaling pathway

KEGG Pathway Links

KEGG Pathway ID	Description
hsa05202	Transcriptional misregulation in cancer

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_150320	Synthesis of Lipoxins (LX)
REACT_150149	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)