LMPD Database

LMP000453

Gene Information

Entrez Gene ID	1571
Gene Name	cytochrome P450, family 2, subfamily E, polypeptide 1
Gene Symbol	CYP2E1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005789	TAS:Reactome	C	endoplasmic reticulum membrane
GO:0000139	IEA:Ensembl	C	Golgi membrane
GO:0031227	IEA:Ensembl	C	intrinsic component of endoplasmic reticulum membrane
GO:0005739	IEA:Ensembl	C	mitochondrion
GO:0019899	IPI:BHF-UCL	F	enzyme binding
GO:0020037	IDA:UniProtKB	F	heme binding
GO:0005506	IEA:InterPro	F	iron ion binding
GO:0004497	IDA:BHF-UCL	F	monooxygenase activity
GO:0016491	IDA:BHF-UCL	F	oxidoreductase activity
GO:0016709	TAS:UniProtKB	F	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0016712	IEA:Ensembl	F	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019825	TAS:ProtInc	F	oxygen binding
GO:0017144	IDA:BHF-UCL	P	drug metabolic process
GO:0046483	IDA:BHF-UCL	P	heterocycle metabolic process
GO:0016098	IDA:BHF-UCL	P	monoterpenoid metabolic process
GO:0055114	IDA:BHF-UCL	P	oxidation-reduction process
GO:0042493	IEA:Ensembl	P	response to drug
GO:0045471	IEA:Ensembl	P	response to ethanol
GO:0010243	IEA:Ensembl	P	response to organonitrogen compound
GO:0010193	IEA:Ensembl	P	response to ozone
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0008202	IMP:BHF-UCL	P	steroid metabolic process
GO:0006641	IEA:Ensembl	P	triglyceride metabolic process
GO:0006805	TAS:Reactome	P	xenobiotic metabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
hsa05204	Chemical carcinogenesis
hsa04932	Non-alcoholic fatty liver disease (NAFLD)