LipidLynxX

A data transfer hub to support integration of large scale lipidomics datasets

Description

LipidLynxX was developed to provide efficient and accurate data transfer between analytical lipidomics datasets and data integration tools. It consists of three main modules supporting the conversion of diverse lipid annotations deriving from experimental lipidomics to unified identifier of user choice (Converter), cross-matching and equalizing lipid identifications obtained at different levels of structural confirmation (Equalizer), and mapping of annotated lipids to identifiers in a collection of databases and knowledge bases such as LIPID MAPS, SwissLipids, KEGG, Rhea, UniprotKB etc. that can be connected to ontology, pathway and network analysis workflows (Linker). LipidLynxX has built-in support to read and generate abbreviation of lipids while keeping the information e.g. modifications types and positions to perform hierarchical comparison. Based on this, LipidLynxX can reduce the over reporting of lipid identifiers and obtain associated identifiers from multiple databases. LipidLynxX provides a high-thoughput solution to format large-scale lipidomics identifiers and assist data integration workflows.