Highlights from the Lipid Analysis Literature - 2025

The following references were collected as part of a weekly literature search that reflects my (former) personal research interests. However, most mainstream lipid analytical topics are covered. Among the exceptions are "steroidal hormones", "prostanoids", "fat-soluble vitamins" and "terpenoids", although some papers in these categories may be posted. My intention is to list only those papers that exhibit novel analytical methodology as opposed to tried and tested methods, although this may appear to introduce a bias towards modern mass spectrometry techniques. Some papers in press may be listed here without the full citation, but the DOI address should still be valid, and they may be updated later. References are listed alphabetically by the first author.

New references are added at approximately monthly intervals by merging with the existing references. The most recent references of all will be found in the web page - "This month's references".

Abe, A., Hinkovska-Galcheva, V. and Shayman, J.A. Assessment of bis(monoacylglycerol)phosphate isomers by thin layer chromatography using a modified solvent system. Biochem. Biophys. Rep., 44, 102303 (2025); DOI.
Abreu, S., Prost, B., Solgadi, A. and Chaminade, P. Comparison of electrospray ionization-lithium adduct formation and atmospheric pressure chemical ionization for lipid analysis by normal phase liquid chromatography. J. Chromatogr. A, 1756, 466058 (2025); DOI.
Amer, S., Jiang, L.X., Iqfath, M., Weigand, M.R. and Laskin, J. Isomer-selective mass spectrometry imaging using nanospray desorption electrospray ionization (Nano-DESI). Acc. Chem. Res., 58, 3281-3293 (2025); DOI.
Amer, S., Unsihuay, D., Yang, M.X. and Laskin, J. Universal photosensitizer for isomer-selective lipid imaging with high molecular coverage. Anal. Chem., 97, 7071-7078 (2025); DOI.
An, N., Mei, P.C., Li, A., Fu, X.F., Wu, X.Z., Jiang, H.P., Zhu, Q.F. and Feng, Y.Q. Derivatization-assisted acoustic ejection mass spectrometry for high-throughput FAHFA prescreening. Anal. Chem., 97, 9613-9619 (2025); DOI.
Araújo, A.R.D., Buvry, O., Antonny, B. and Debayle, D. Separation of polar and neutral lipids from mammalian cell lines by high-performance thin-layer chromatography. J. Chromatogr. A, 1741, 465610 (2025); DOI.
Araujo, P., Espe, M., Holen, E., Austgulen, M.H. and Iqbal, S. Cross-species comparison of resolvin E and resolvin D biosynthesis: Quantification by liquid chromatography mass spectrometry in fish and human cells exposed to alpha-linolenic acid, eicosapentaenoic acid, and docosahexaenoic acid. J. Chromatogr. B, 1264, 124729 (2025); DOI.
Asadian, M., Croslow, S.W., Trinklein, T.J., Rubakhin, S.S., Lam, F. and Sweedler, J.V. High-throughput fluorescence-guided sequential single-cell MALDI-ICC mass spectrometry. Anal. Chem., 97, 15864-15872 (2025); DOI.
Bale, N.J., Koenen, M., Ding, S. and Damste, J.S.S. N-glyceroyl alkylamine phosphoglycolipids dominate the lipidome of several Bacillota bacteria. System. Appl. Microbiol., 48, 126609 (2025); DOI.
Bang, S., Shin, Y.H., Park, S.M., Deng, L., Williamson, R.T., Graham, D.B., Xavier, R.J. and Clardy, J. Unusual phospholipids from Morganella morganii linked to depression. J. Am. Chem. Soc., 147, 2998-3002 (2025); DOI.
Barbeito, J., Mastrogiovanni, M., García-Roche, M., Mendoza, A., Rubbo, H., Carriquiry, M. and Trostchansky, A. Bovine milk as a source of nitro-conjugated linoleic acid. Int. J. Dairy Techn., 78, e13155 (2025); DOI.
Bauer, V., Haspel, T., Beifuss, U. and Vetter, W. Methyl substituted long chain 1,4-O-bridged-1,3-dienes-novel suitable internal standards for the GC/MS analysis of furan fatty acids in fish oil. J. Am. Oil Chem. Soc., 102, 1525-1533 (2025); DOI.
Beck, O., Barroso, M., Hermansson, S., Widen, C., Wallin, C., Nilsson-Wallmark, C. and de Bejczy, A Volumetric dried blood spots for determination of phosphatidylethanol: Validation of a liquid chromatography tandem mass spectrometry method and clinical application. Drug Test. Anal., 17, 231-237 (2025); DOI.
Beveridge, C., Iyer, S., Randolph, C.E., Muhoberac, M., Manchanda, P., Walker, K.A., Tichy, S. and Chopra, G. CLAW-MRM: comprehensive lipidomics automation workflow for multiple reaction monitoring using large language models. Anal. Chem., 97, 19409-19418 (2025); DOI.
Bilbao, A. The future of a myriad of accelerated biodiscoveries lies in AI-powered mass spectrometry and multiomics integration. J. Mass Spectrom., 60, e5157 (2025); DOI.
Biricioiu, M.R., Sarbu, M., Ica, R., Vukelic, Z., Clemmer, D.E. and Zamfir, A.D. Advanced profiling and structural analysis of anencephaly gangliosides by ion mobility tandem mass spectrometry. Biochimie, 232, 91-104 (2025); DOI.
Biricioiu, M. and others. Advanced ganglioside characterization in epileptic human hippocampus by travelling waves ion mobility tandem mass spectrometry. J. Mass Spectrom., 60, e5190 (2025); DOI.
Boerkamp, V.J.P., Hennebelle, M., Vincken, J.P. and van Duynhoven, J.P.M. Comprehensive quantitative profiling of vegetable oil oxidation products by NMR-based oxylipidomics. Food Res. Int., 202, 115612 (2025); DOI.
Bonney, J.R., Stratton, A.E., Guo, Y.C., Eades, C.B. and Prentice, B.M. Imaging mass spectrometry of sulfatide isomers from rat brain tissue using gas-phase charge inversion ion/ion reactions. J. Am. Soc. Mass Spectrom., 36, 119-126 (2025); DOI.
Bookmeyer, C.H.M., Correig, F.X., Masana, L., Magni, P., Yanes, O. and Vinaixa, M. Advancing atherosclerosis research: the power of lipid imaging with MALDI-MSI. Atherosclerosis, 403, 119130 (2025); DOI.
Böttcher, C., Gorzolka, K., Himmighofen, P. and Meiners, T. Analysis of acyl solamines in tuber periderm of cultivated and wild potatoes using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry. J. Mass Spectrom., 60, e5177 (2025); DOI.
Brash, A.R., Boeglin, W.E., Calcutt, M.W., Voehler, M., Stec, D.F. and Harris, T.M. Analysis of the thiol adduction of linoleate 9,10-dihydroxy-11E-13-ketones of the mammalian skin barrier and their cyclization to hemiketals. ACS Omega, 10, 40512-40520 (2025); DOI.
Brockbals, L., Ueland, M., Fu, S.L. and Padula, M.P. Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets. Talanta, 286, 127442 (2025); DOI.
Camunas-Alberca, S.M., Taha, A.Y., Gradillas, A. and Barbas, C. Comprehensive analysis of oxidized arachidonoyl-containing glycerophosphocholines using ion mobility spectrometry-mass spectrometry. Talanta, 289, 127712 (2025); DOI.
Cao, Y. and others. Three-layer electrospray constructing charged microdroplets for online derivatization and position identification of lipid C=C bonds. Anal. Chem., 97, 10190-10199 (2025); DOI.
Cao, Y.P., Li, X., Wang, K., Wu, X.P., Zhang, J. and Wang, F.E. Simultaneous determination of 23 trans fatty acids in common edible oils by gas chromatography-mass spectrometry. Separations, 12, 171 (2025); DOI.
Carlos, J., Gosset-Erard, C., Salpin, J.Y. and Poyer, S. Electron transfer dissociation of alkali-cationized phosphatidylcholines allows easy double bonds and sn-1/sn-2 localizations. Rapid Commun. Mass Spectrom., 39, e9956 (2025); DOI.
Carpanedo, L., Wende, L.M., Goebel, B., Häfner, A.K., Chromik, M.A., Kampschulte, N., Steinhilber, D. and Schebb, N.H. Substrate-dependent incorporation of 15-lipoxygenase products in glycerophospholipids: 15-HETE and 15-HEPE in PI, 17-HDHA in plasmalogen PE, and 13-HODE in PC. J. Lipid Res., 66, 100841 (2025); DOI.
Cavo, I., Fresnedo, O., Mosteiro, L., López, J.I., Larrinaga, G. and Fernández, J.A. Lipid imaging mass spectrometry: Towards a new molecular histology. Biochim. Biophys. Acta, Lipids, 1870, 159568 (2025); DOI.
Chakraborti, S. and Sistla, J.C. Mycolic acid-like lipids act as substrates for Mycobacterium marinum melH. ACS Omega, 10, 41221-41232 (2025); DOI.
Chao, H.C. and Mcluckey, S.A. Altering lipid A precursor ion types in the gas phase for in-depth structural elucidation via tandem mass spectrometry. Anal. Chem., 97, 1861-1869 (2025); DOI.
Chen, L.X., Yu, W.J., Zhao, J.L., Jia, S.N. and Hu, L.H. Molecular imprinting of phospholipids for targeted cell and exosome recognition. Anal. Chem., 97, 9953-9960 (2025); DOI.
Chen, T. Wang, C.F., Li, Z.G.,Yang, H., Yang, Y. and Xie, S.C. A novel protocol for extracting 3-hydroxy fatty acids from soil with microwave-assisted acid digestion. Org. Geochem., 204, 104988 (2025); DOI.
Chen, Y. and others. Structural annotation method for locating sn- and C=C positions of lipids using liquid chromatography-electron impact excitation of ions from organics (EIEIO)-mass spectrometry. Anal. Chem., 97,4998-5007 (2025); DOI.
Chen, Y. and others. Novel equivalent carbon number strategy for large-scale lipidomics data analysis via ultrahigh-performance liquid chromatography-orbitrap astral mass spectrometry. Anal. Chem., 97, 15550-15555 (2025); DOI.
Cheong, B.S., He, C.C.Z., Laurenson, I., Claxton, P., Kostrzewa, M., Drobniewski, F. and Larrouy-Maumus, G. Performance of direct detection of Mycobacterium tuberculosis within Mycobacterium tuberculosis complex by routine MALDI-TOF for diagnosis using species-specific lipid fingerprint. Microbiol. Spectrum, 13, e0035625 (2025); DOI.
Chevolleau, S. and others. Significant improvements in targeted UHPLC-ESI-MS/MS analysis of the reactive aldehydes 4-hydroxy-2(E)-nonenal and 4-hydroxy-2(E)-hexenal and application to rat serum. J. Chromatogr. B, 1265, 124747 (2025); DOI.
Chiu, D.C., Cho, Y.T., Lin, H.N. and Baskin, J.M. Photoaffinity labeling reveals a role for the unusual triply acylated phospholipid N-acylphosphatidylethanolamine in lactate homeostasis. J. Am. Chem. Soc., 147, 33386-33394 (2025); DOI.
Chocholousková, M. and Torta, F. Fast and comprehensive lipidomic analysis using supercritical fluid chromatography coupled with low and high resolution mass spectrometry. J. Chromatogr. A, 1745, 465742 (2025); DOI.
Cifková, E., Neuerová, Z. and Lísa, M. Reversed-phase liquid chromatography/mass spectrometry approach for (un)targeted analysis of polar to mid-polar metabolites. Talanta, 291, 127853 (2025); DOI.
Clarke, H.A. and others. Spatial mapping of the brain metabolome lipidome and glycome. Nature Commun., 16, 4373 (2025); DOI.
Colin-Leitzinger, C. and others. A machine learning framework for classifying lipids in untargeted metabolomics using mass-to-charge ratios and retention times. Metabolomics, 21, 151 (2025); DOI.
Cousineau, S.L., Sarikahya, M.H., Jurcic, K., Laviolette, S.R., Hardy, D.B. and Yeung, K.K.C. Monitoring the degree of in-source phospholipid fragmentation during MALDI mass spectrometry imaging. Anal. Chim. Acta, 1367, 344297 (2025); DOI.
Croslow, S.W., Sirois, C.H. and Sweedler, J.V. Factorial-design-based optimization of a commercial MALDI-2 timsTOF mass spectrometer for lipid analysis. J. Am. Soc. Mass Spectrom., 36, 942-951 (2025); DOI.
Dai, Y.C., Zhu, B.C., Yan, X.T., Xie, X.B., Zhan, Z.X. and Lv, Y. Iridium isotope tag-assisted LC-MS method for global profiling and quantification of nonvolatile serum fatty acids in nonalcoholic fatty liver mice. Anal. Chem., 97, 7055-7062 (2025); DOI.
Damerau, A., Ahonen, E., Kortesniemi, M., Gudmundsson, H.G., Yang, B.R., Haraldsson, G.G. and Linderborg, K.M. Eicosapentaenoic Acid Is most oxidatively stable in the sn-2 position of triacylglycerols compared with sn-3 and sn-1. Eur. J. Lipid Sci. Technol., 127, e70016 (2025); DOI.
Daramola, O., Gautam, S., Bennett, A.I., Goli, M., Guiterrez-Reyes, C.D., Wang, J.Y. and Mechref, Y. LC-MS/MS of permethylated o-glycans, free oligosaccharides, and glycosphingolipid glycans using mesoporous graphitized carbon column. J. Sep. Sci., 48, e70187 (2025); DOI.
Das, U.S. and Fitzgerald, G.A. Chiral clues to lipid identity. J. Lipid Res., 66, 100710 (2025); DOI.
de Bruin, C.R., de Bruijn, W.J.C., Hemelaar, M.A., Vincken, J.P. and Hennebelle, M. Separation of triacylglycerol (TAG) isomers by cyclic ion mobility mass spectrometry. Talanta, 281, 126804 (2025); DOI.
de la Torre, R.S., Montero-Vílchez, T., García-Gavín, J. and Arias-Santiago, S. Current insights on lipidomics in dermatology: a systematic review. J. Invest. Derm., 145, 1105-1116.e6 (2025); DOI.
Demtschuk, M. and Heinz, P. Systematic literature review of different methods for sample preparation for the quantification of coenzyme Q10 in human blood samples by HPLC. Acta Chromatogr., in press (2025); DOI.
Deng, L.L., Zhang, D., Rorrer, L.C., Slemko, M.J. and Debord, D. Iterative SLIM (itSLIM) for ultrahigh resolution targeted ion mobility analysis. J. Am. Soc. Mass Spectrom., 36, 2578-2585 (2025); DOI.
Dhakal, S., Nalder, T.D., Marshall, S.N. and Barrow, C.J. Analytical approaches to the rapid characterisation of marine glycolipids in bioproduct discovery. Marine Drugs, 23, 352 (2025); DOI.
Ding, Q., Tian, X.Y., Wu, W.S., Yu, F.J., Shao, Z.Q. and Zeng, Z. The metabolic landscape of tomato roots during arbuscular mycorrhizal symbiosis reveals lipid-related metabolic rewiring. Plant Cell Rep., 44, 230 (2025); DOI.
Dong, L. and others. A dominant subgroup of marine Bathyarchaeia assimilates organic and inorganic carbon into unconventional membrane lipids. Nature Microbiol., 10, 2579-2590 (2025); DOI.
dos Santos, G.F. and others. Advancing stable isotope analysis with Orbitrap-MS for fatty acid methyl esters and complex lipid matrices. J. Am. Soc. Mass Spectrom., 36, 1527-1535 (2025); DOI.
Dou, P., Yang, H., Bao, M., Li, Y.L., Liu, X.Y., Liang, X.X., Lu, X., Fan, J.H. and Xu, G.W. Laser capture microdissection-assisted gas chromatography-triple-quadruple mass spectrometry for spatial metabolic profiling of esophageal squamous cell carcinoma. J. Pharm. Biomed. Anal., 265, 117036 (2025); DOI.
Dressman, J.W., Bayram, M.F., Angel, P.M., Drake, R.R. and Mehta, A.S. Single-cell multiomic MALDI-MSI analysis of lipids and N-Glycans through affinity array capture. Anal. Chem., 97, 12493-12502 (2025); DOI.
Ducatez, F. and others. Lysosphingolipid quantitation in plasma and dried-blood spots using targeted high-resolution mass spectrometry. J. Clin. Lab. Anal., 39, e25131 (2025); DOI.
Dyall, S.C. and Plourde, M. Omega-3 polyunsaturated fatty acids in neurodegenerative disorders: Mixed designs = mixed results. Prog. Lipid Res., 100, 101356 (2025); DOI.
Ebbini, M., Wang, Z.C., Zhang, H., Lu, K.H., Huang, P.H., Kaminsky, C.J., Puglielli, L. and Li, L.J. On-tissue chemical derivatization for mass spectrometry imaging of fatty acids with enhanced detection sensitivity. Biomolecules, 15, 366 (2025); DOI.
Emaus, K.J., Dunbar, C.A., Caruso, J., Ruotolo, B.T., Wider, J.M. and Sanderson, T.H. Analysis of neuronal cardiolipin and monolysocardiolipin from biological samples with cyclic ion mobility mass spectrometry. Front. Physiol., 16, 1592008 (2025); DOI.
Ersalena, V.F., Kitaoka, N. and Matsuura, H. Unveiling the presence of jasmonoyl-l-isoleucine in 3 species of moss belonging to Bryophytes. Biosci. Biotechn. Biochem., 89, 1177-1181 (2025); DOI.
Fabian, J I. and Lehr, M. Quantitative profiling of lipid mediators in sperm cells through on-line dilution on-line polymer matrix-based solid-phase extraction liquid chromatography with mass spectrometric detection. Anal. Methods, 17, 7643-7651 (2025); DOI.
Fahs, H.Z. and others. A new class of natural anthelmintics targeting lipid metabolism. Nature Commun., 16, 305 (2025); DOI.
Fanti, F., Sergi, M. and Compagnone, D. LC-MS/MS based analytical strategies for the detection of lipid peroxidation products in biological matrices. J. Pharm. Biomed. Anal., 256, 116681 (2025); DOI.
Farrow, M.A. and others. A lipid atlas of the human kidney. Sci. Adv., 11, eadu3730 (2025); DOI.
Felippe, T.V.D. and others. High-resolution targeted mass spectrometry for comprehensive quantification of sphingolipids: clinical applications and characterization of extracellular vesicles. Anal. Biochem., 698, 115732 (2025); DOI.
Foest, D., Franzke, J. and Brandt, S. Quasi-simultaneous identification of polar and neutral lipids in mass spectrometry by kHz switching of electrospray and plasma ionization. Anal. Chem., 97, 2011-2018 (2025); DOI.
Fougère, L., Moreau, H., Mirande-Bret, C., Fouillen, L I. and Boutte, Y. PhosphoLIMBO: an easy and efficient protocol to separate and analyze phospholipids by HPTLC from plant material. Bio-Protocol, 15, e5434 (2025); DOI.
Fredriksen, T.R., Holbrook, J.H., Rosas, L., Angeles-Lopez, Q.D., Mora, A.L., Rojas, M. and Hummon, A.B. Light-reactive norharmane derivatization of lipid isomers by matrix-assisted laser desorption/ionization mass spectrometry. Anal. Chem., 97, 6001-6008 (2025); DOI.
Freeman, L.M., Rush, J.E., Berridge, B.R., Mitchell, R.N. and Martinez-Romero, E.G. Dogs with diet-associated dilated cardiomyopathy have higher urine di-docosahexaenoyl (22:6)-bis(monoacylglycerol)phosphate, a biomarker of phospholipidosis. Am. J. Vet. Res., 86, 211 (2025); DOI.
Fu, R.R. and others. Tracking the geometric and positional isomerization of lipid C=C bonds in the bacterial stress responses by mass spectrometry. Anal. Chem., 97, 555-564 (2025); DOI.
Gao, X.H., Yin, T.L., Li, Y., Shi, S.F., Liu, F.L., Li, M.J., Liu, R.X., Liu, Q. and Xu, Y.L. Assessment of serum metabolism and eicosanoid profiling in pediatric asthma and bronchiolitis via liquid chromatography-mass spectrometry. Rapid Commun. Mass Spectrom., 39, e9955 (2025); DOI.
Gao, X.Y. and Zhao, X. In-depth characterization of acylcarnitines: utilizing nitroxide radical-directed dissociation in tandem mass spectrometry. Anal. Bioanal. Chem., 417, 3327-3335 (2025); DOI.
Gao, X.Y., Liu, .CL. and Zhao, X. Isomer-resolved characterization of acylcarnitines reveals alterations in type 2 diabetes. Anal. Chim. Acta, 1351, 343856 (2025); DOI.
Garcia, C.J. and others. Novel insights into the human gut microbially conjugated bile acids: the new diversity of the amino acid-conjugated derivatives. J. Agric. Food Chem., 31, 19460–19473 (2025); DOI.
Gatti, N., Greco, V., Cuzzocrea, S., Crupi, R., Gugliandolo, E. and Giuffrida, A. Time-controlled online SPE: strategic approach for N-acylethanolamines quantification in complex matrices. J. Chromatogr. A, 1763, 466449 (2025); DOI.
Gavard, P., Gavard, A., Perquis, L., Collin, F. and Couderc, F. Recent advances in lipid analysis by capillary electromigration methods, 2019-2024. J. Chromatogr. A, 1746, 465756 (2025); DOI.
Genva, M., Mirande-Bret, C. and Fouillen, L. A new approach to detect and semi-quantify all molecular species and classes of anionic phospholipids simultaneously in plant samples. Bio-Protocol, 15, e5282 (2025); DOI.
Geraldo, P.A., do Nascimento, M.P., Berlande, B.M., de Souza, J.C.Q., Adriano, L.H.C. and de Oliveira, M.A.L. Investigation of fatty acids in biological fluid samples and analysis by capillary electrophoresis: state of the art and applications. Electrophoresis, 46, 524-538 (2025); DOI.
Gish, A., Wiart, J.F., Richeval, C., Allorge, D. and Gaulier, J.M. Simultaneous analysis of four endocannabinoids and endocannabinoid congeners together with delta-9 tetrahydrocannabinol and related metabolites in dried blood spots. J. Pharm. Biomed. Anal., 265, 116991 (2025); DOI.
Gomonit, M.M., Roman, M., Skillman, B.N., Truver, M.T. and Kronstrand, R. Quantification of phosphatidylethanol 16:0/18:1 in blood using supercritical fluid chromatography-tandem mass spectrometry. J. Anal. Toxicol., 49, 289-298 (2025); DOI.
Gonzalez-Riano, C., León-Espinosa, G., Regalado-Reyes, M., García, A., Defelipe, J. and Barbas, C. Advanced lipidomics using UHPLC-ESI-QTOF-MS/MS reveals novel lipids in hibernating syrian hamsters. J. Chromatogr. A, 1743, 465692 (2025); DOI.
Good, C.J., Bowman, A.P., Klein, C., Awwad, K., Buck, W.R., Yang, J.H. and Wagner, D.S. Spatial mapping of gangliosides and proteins in amyloid beta plaques at cellular resolution using mass spectrometry imaging and MALDI-IHC. J. Mass Spectrom., 60, e5161 (2025); DOI.
Grossert, J.S. and Ramaley, L. Unified fragmentation pathways of lithiated, longer-chain acylglycerols can be identified from tandem mass spectrometry and density functional computations. J. Am. Soc. Mass Spectrom., 36, 368-378 (2025); DOI.
Guerra, I.M.S. and others. Lipidomic profiling of red blood cells in the mitochondrial fatty acid beta-oxidation disorder MCADD reveals phospholipid and sphingolipid dysregulation. J. Proteome Res., 24, 4631-4642 (2025); DOI.
Gukalova, B., Krims-Davis, K., Sevostjanovs, E., Leduskrasta, A., Konrade, I., Dambrova, M. and Liepinsh, E. LC-MS/MS-based simultaneous quantification of acylcarnitines, eicosapentaenoic acid, and docosahexaenoic acid: exploring potential biomarkers in human plasma. Anal. Bioanal. Chem., 417, 2193-2206 (2025); DOI.
Guo, Y.C., Specker, J.T., Gaikwad, P.B., Miranda-Quintana, R.A. and Prentice, B.M. Characterizing the energy surfaces of competing pathways in gas-phase charge inversion ion/ion reactions involving cationized lipids and anionic diacids. J. Am. Soc. Mass Spectrom., 36, 2103-2116 (2025); DOI.
Gusenda, C., Berlage, S., Burkhart, I., Chagot, B., Weissman, K.J., Schwalbe, H. and Grininger, M. Protocol for the purification, analysis, and handling of acyl carrier proteins from type I fatty acid and polyketide synthases. Star Protocols, 6, 103762 (2025); DOI.
Guttorm, S.J.T., Wilson, S.R.H., Amundsen, E.K., Rootwelt, H. and Elgstoen, K.B.P. Scheduled data-dependent acquisition MS provides enhanced identification and sensitivity in clinical lipidomics. Anal. Chim. Acta, 1371, 344426 (2025); DOI.
Hamzah, K.A., Turner, N., Nichols, D. and Ney, L.J. Advances in targeted liquid chromatography-tandem mass spectrometry methods for endocannabinoid and N-acylethanolamine quantification in biological matrices: A systematic review. Mass Spectrom. Rev., 44, 513-538 (2025); DOI.
He, F.F., Liu, G., Huang, D.Y., Wang, Z., Zhao, A.Z. and Wang, X.Y. Liquid chromatography-mass spectrometry analysis of major lipid species in Bacteroides thetaiotaomicron VPI 5482. Systems Microbiol. Bioman., 5, 409-420 (2025); DOI.
Helms, A. and Brodbelt, J.S. Progress in characterization of lipopolysaccharides and lipid A by mass spectrometry. Mass Spectrom. Rev., in press (2025); DOI.
Hendriks, T.F.E., Birmpili, A., de Vleeschouwer, S., Heeren, R.M.A. and Cuypers, E. Integrating rapid evaporative ionization mass spectrometry classification with matrix-assisted laser desorption ionization mass spectrometry imaging and liquid chromatography-tandem mass spectrometry to unveil glioblastoma overall survival prediction. ACS Chem. Neurosci., 16, 1021-1033 (2025); DOI.
Hermeling, S., Plagge, J., Krautbauer, S., Ecker, J., Burkhardt, R. and Liebisch, G. Rapid quantification of murine bile acids using liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem., 417, 687-696 (2025); DOI.
Hoffmann, N. and others. Introduction of a lipidomics scoring system for data quality assessment. J. Lipid Res., 66, 100817 (2025); DOI.
Homer, N.Z.M., Andrew, R. and Gilroy, D.W. Review of methodology and re-analysis of lipidomic data focusing on specialised pro-resolution lipid mediators (SPMs) in a human model of resolving inflammation. Int. J. Exp. Path., 106, e12523 (2025); DOI.
Hondo, T., Miyake, Y. and Toyoda, M. Algorithm-driven chromatographic method for prostaglandin isomer identification via tandem mass spectrometry. J. Am. Soc. Mass Spectrom., 36, 1729-1736 (2025); DOI.
Hose, J., Juebner, M., Thevis, M. and Andresen-Streichert, H. Assessment and cross-validation of calibration transferability between dried blood spot sampling devices for accurate quantification of phosphatidylethanol. Anal. Bioanal. Chem., 417, 3803-3811 (2025); DOI.
Hotz, L., Zartmann, A., Noack, I., Drees, L.J., Kuschow, M.K., Heinrich, M.R., Janssen, H.G. and Hammann, S. Enzymatically formed fatty acid hydroperoxides determined through GC-MS analysis of enantiomeric excess of hydroxy fatty acids after reduction and ibuprofen derivatization. Eur. J. Lipid Sci. Technol., 127, e202400065 (2025); DOI.
Hu, D.N., Lui, T.Y., Chen, X.F. and Chan, T.W.D. A mass spectrometric study of the role of water in the Paterno-Buchi (PB) reaction between 2-acetylpyridine and unsaturated fatty acids. J. Am. Soc. Mass Spectrom., 36, 1366-1376 (2025); DOI.
Hu, D.N., Lui, T.Y., Chen, X.F. and Chan, T.W.D. Determination of double bond positions in unsaturated fatty acids using permanganate oxidation and tandem mass spectrometry of CuIICl+ adducted ions. Anal. Chem., 97, 7315-17323 (2025); DOI.
Hu, T., Tang, Y., Han, F.F., Ding, X I. and An, Z.L. Development and validation of a machine learning-based retention time prediction model for glycosphingolipids in UHPLC-HRMS analysis. Microchem. J., 218, 115318 (2025); DOI.
Huang, X.Y., Ali, A., Yachioui, D.E.I., Le Dévédec, S.E. and Hankemeier, T. Lipid dysregulation in triple negative breast cancer: Insights from mass spectrometry-based approaches. Prog. Lipid Res., 98, 101330 (2025); DOI.
Huang, Y.F., Wang, M.X., Yang, Z.Q., Wang, X.T., Wang, X.X. and He, F. Determination of nine prostaglandins in the arachidonic acid metabolic pathway with UHPLC-QQQ-MS/MS and application to in vitro and in vivo inflammation models. Front. Pharm., 16, 1595059 (2025); DOI.
Hynds, H.M., Carpenter, J.M. and Hines, K.M. Rapid multi-omics for bacterial identification using flow injection-ion mobility-mass spectrometry. Anal. Chem., 97, 13809-13816 (2025); DOI.
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