Uncovering complexity of natural epilipidomes
About Dr Maria Fedorova
Maria Fedorova studied Biochemistry at Saint-Petersburg State University, Russia and obtained her PhD at Faculty of Chemistry and Mineralogy, Leipzig University, Germany. Now she is a group leader at the Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, at the University of Leipzig. Her research is focused on development and optimization of chromatography and mass spectrometry methods for analysis of lipids and their modified forms. Dr Fedorova group works on implementation of high throughput LC-MS methods in discovery lipidomics targeting in-depth identification and quantification of human lipidome in variety of tissues. By combining lipidomics data with investigation of related proteins and protein post-translational modifications via systems medicine approach, Dr Fedorova aims for a deeper understanding of pathophysiology of obesity, insulin resistance, type II diabetes and cardiovascular disorders. Another focus of Dr Fedorova’s research is the development and application of mass spectrometry-based methods for analysis of protein and lipid modifications, including lipid-protein adducts. She is working to understand the role of redox lipid and protein signaling in the onset and progression of human disorders associated with chronic inflammation, including cardiovascular and metabolic diseases.