Structure Database (LMSD)
Common Name
11S-HETE
Systematic Name
11S-hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic acid
Synonyms
3D model of 11S-HETE
Please note: Where there are chiral atoms but the stereochemistry is undefined, the 3D model takes an arbitrary conformation
Classification
Biological Context
11(S)-HETE is an oxylipin and the (S) enantiomer of 11(R)-HETE . It is formed non-enzymatically from arachidonic acid .1 Levels of 11(S)-HETE are higher than those of 11(R)-HETE in isolated human plasma and serum and in LPS-stimulated isolated human plasma. Serum labels of 11(S)-HETE decrease in patients with allergic rhinitis after one year of double-mite subcutaneous immunotherapy (DM-SCIT) and are associated with an improved quality of life in regards to rhinoconjunctivitis.2
This information has been provided by Cayman Chemical
References
String Representations
InChiKey (Click to copy)
GCZRCCHPLVMMJE-YZGNWCGPSA-N
InChi (Click to copy)
InChI=1S/C20H32O3/c1-2-3-4-5-7-10-13-16-19(21)17-14-11-8-6-9-12-15-18-20(22)23/h6-7,9-11,13-14,16,19,21H,2-5,8,12,15,17-18H2,1H3,(H,22,23)/b9-6-,10-7-,14-11-,16-13+/t19-/m1/s1
SMILES (Click to copy)
C(O)(=O)CCC/C=C\C/C=C\C[C@H](O)/C=C/C=C\CCCCC
Other Databases
Calculated Physicochemical Properties
Heavy Atoms
23
Rings
0
Aromatic Rings
0
Rotatable Bonds
14
Van der Waals Molecular Volume
367.73
Topological Polar Surface Area
57.53
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
3
logP
5.47
Molar Refractivity
97.94
Admin
Created at
-
Updated at
-