Gene/Proteome Database (LMPD)

LMPD ID
LMP014935
Gene ID
574129
Species
Macaca mulatta (Rhesus monkey)
Gene Name
signal transducer and activator of transcription 5A
Gene Symbol
STAT5A
Synonyms
STAT5;
Alternate Names
signal transducer and activator of transcription 5A;
Chromosome
16
Map Location
chromosome:16

Proteins

signal transducer and activator of transcription 5A isoform 1
Refseq ID NP_001265287
Protein GI 508772622
UniProt ID F7G8V4
mRNA ID NM_001278358
Length 794
Protein sequence is identical to GI:297273065 (mRNA isoform)
signal transducer and activator of transcription 5A isoform 2
Refseq ID NP_001265276
Protein GI 508772624
mRNA ID NM_001278347
Length 764
Protein sequence is identical to GI:297273067 (mRNA isoform)
Refseq ID XP_001109557
Protein GI 297273067
UniProt ID F7G8V4
mRNA ID XM_001109557
Length 764
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFGPLAQLSPQERLSRETALRQKQVSLETWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEKMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPERNLWNLKPFTTRDFSIRSLADRLGDLSYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVNASADAGSGSATYMDQAPSPAVCPQAHYNMYPQNPDPVLDQDGEFDLDETMDVARHVEELLRRPMDSLDSRLSPPAGLFTSARGSLS
Refseq ID XP_002800522
Protein GI 297273065
UniProt ID F7G8V4
mRNA ID XM_001109557
Length 794
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFGPLAQLSPQERLSRETALRQKQVSLETWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEKMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPERNLWNLKPFTTRDFSIRSLADRLGDLSYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVNASADAGSGSATYMDQAPSPAVCPQAHYNMYPQNPDPVLDQDGEFDLDETMDVARHVEELLRRPMDSLDSRLSPPAGLFTSARGSLS

Gene Information

Entrez Gene ID
574129
Gene Name
signal transducer and activator of transcription 5A
Gene Symbol
STAT5A
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-SubCell C cytoplasm
GO:0005634 IEA:UniProtKB-SubCell C nucleus
GO:0000979 IEA:Ensembl F RNA polymerase II core promoter sequence-specific DNA binding
GO:0005509 IEA:InterPro F calcium ion binding
GO:0003700 IEA:InterPro F sequence-specific DNA binding transcription factor activity
GO:0004871 IEA:Ensembl F signal transducer activity
GO:0006103 IEA:Ensembl P 2-oxoglutarate metabolic process
GO:0060397 IEA:Ensembl P JAK-STAT cascade involved in growth hormone signaling pathway
GO:0048541 IEA:Ensembl P Peyer's patch development
GO:0033077 IEA:Ensembl P T cell differentiation in thymus
GO:0043029 IEA:Ensembl P T cell homeostasis
GO:0000255 IEA:Ensembl P allantoin metabolic process
GO:0097011 IEA:Ensembl P cellular response to granulocyte macrophage colony-stimulating factor stimulus
GO:0006101 IEA:Ensembl P citrate metabolic process
GO:0006600 IEA:Ensembl P creatine metabolic process
GO:0046449 IEA:Ensembl P creatinine metabolic process
GO:0046543 IEA:Ensembl P development of secondary female sexual characteristics
GO:0046544 IEA:Ensembl P development of secondary male sexual characteristics
GO:0060742 IEA:Ensembl P epithelial cell differentiation involved in prostate gland development
GO:0006631 IEA:Ensembl P fatty acid metabolic process
GO:0007565 IEA:Ensembl P female pregnancy
GO:0006549 IEA:Ensembl P isoleucine metabolic process
GO:0007595 IEA:Ensembl P lactation
GO:0019915 IEA:Ensembl P lipid storage
GO:0001553 IEA:Ensembl P luteinization
GO:0061180 IEA:Ensembl P mammary gland epithelium development
GO:0001779 IEA:Ensembl P natural killer cell differentiation
GO:0045647 IEA:Ensembl P negative regulation of erythrocyte differentiation
GO:0033026 IEA:Ensembl P negative regulation of mast cell apoptotic process
GO:0006107 IEA:Ensembl P oxaloacetate metabolic process
GO:0018108 IEA:Ensembl P peptidyl-tyrosine phosphorylation
GO:0045579 IEA:Ensembl P positive regulation of B cell differentiation
GO:0042104 IEA:Ensembl P positive regulation of activated T cell proliferation
GO:0045588 IEA:Ensembl P positive regulation of gamma-delta T cell differentiation
GO:0050729 IEA:Ensembl P positive regulation of inflammatory response
GO:0045086 IEA:Ensembl P positive regulation of interleukin-2 biosynthetic process
GO:0060376 IEA:Ensembl P positive regulation of mast cell differentiation
GO:0070668 IEA:Ensembl P positive regulation of mast cell proliferation
GO:0045931 IEA:Ensembl P positive regulation of mitotic cell cycle
GO:0040018 IEA:Ensembl P positive regulation of multicellular organism growth
GO:0032825 IEA:Ensembl P positive regulation of natural killer cell differentiation
GO:0045954 IEA:Ensembl P positive regulation of natural killer cell mediated cytotoxicity
GO:0045944 IEA:Ensembl P positive regulation of transcription from RNA polymerase II promoter
GO:0038161 IEA:Ensembl P prolactin signaling pathway
GO:0060740 IEA:Ensembl P prostate gland epithelium morphogenesis
GO:0030155 IEA:Ensembl P regulation of cell adhesion
GO:0030856 IEA:Ensembl P regulation of epithelial cell differentiation
GO:0019218 IEA:Ensembl P regulation of steroid metabolic process
GO:0006105 IEA:Ensembl P succinate metabolic process
GO:0019530 IEA:Ensembl P taurine metabolic process
GO:0006351 IEA:UniProtKB-KW P transcription, DNA-templated
GO:0006573 IEA:Ensembl P valine metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ko05221 Acute myeloid leukemia
mcc05221 Acute myeloid leukemia
ko05220 Chronic myeloid leukemia
mcc05220 Chronic myeloid leukemia
ko04012 ErbB signaling pathway
mcc04012 ErbB signaling pathway
ko05166 HTLV-I infection
mcc05166 HTLV-I infection
mcc05161 Hepatitis B
ko04630 Jak-STAT signaling pathway
mcc04630 Jak-STAT signaling pathway
ko05162 Measles
mcc05162 Measles
mcc05200 Pathways in cancer
ko04917 Prolactin signaling pathway
mcc04917 Prolactin signaling pathway
ko05203 Viral carcinogenesis
mcc05203 Viral carcinogenesis

Domain Information

InterPro Annotations

Accession Description
IPR011992 EF-hand domain pair
IPR000980 SH2 domain
IPR013801 STAT transcription factor, DNA-binding
IPR012345 STAT transcription factor, DNA-binding, subdomain
IPR013800 STAT transcription factor, all-alpha
IPR015988 STAT transcription factor, coiled coil
IPR013799 STAT transcription factor, protein interaction
IPR001217 Transcription factor STAT
IPR008967 p53-like transcription factor, DNA-binding

UniProt Annotations

Entry Information

Gene Name
signal transducer and activator of transcription 5A
Species
Rhesus monkey

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Belongs to the transcription factor STAT family.
Similarity Contains 1 SH2 domain.
Subcellular Location Cytoplasm
Subcellular Location Nucleus

Identical and Related Proteins

Unique RefSeq proteins for LMP014935 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
297273065 RefSeq XP_002800522 794 signal transducer and activator of transcription 5A
297273067 RefSeq XP_001109557 764 signal transducer and activator of transcription 5A

Identical Sequences to LMP014935 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP014935 proteins

Reference Database Accession Length Protein Name
GI:508772622 GenBank EHH24983.1 794 Signal transducer and activator of transcription 5A [Macaca mulatta]
GI:508772622 RefSeq XP_002827564.1 764 PREDICTED: signal transducer and activator of transcription 5A isoform X2 [Pongo abelii]
GI:508772622 RefSeq XP_003913115.1 794 PREDICTED: signal transducer and activator of transcription 5A [Papio anubis]
GI:508772622 RefSeq XP_005584300.1 794 PREDICTED: signal transducer and activator of transcription 5A [Macaca fascicularis]