Gene/Proteome Database (LMPD)

LMPD ID
LMP014694
Gene ID
701195
Species
Macaca mulatta (Rhesus monkey)
Gene Name
protein kinase C, beta
Gene Symbol
PRKCB
Synonyms
PRKCB1;
Alternate Names
protein kinase C beta type;
Chromosome
20
Map Location
chromosome:20
EC Number
2.7.11.13

Proteins

protein kinase C beta type
Refseq ID NP_001244443
Protein GI 383873165
UniProt ID F7BYH7
mRNA ID NM_001257514
Length 673
Protein sequence is identical to GI:109127928 (mRNA isoform)
Refseq ID XP_001096447
Protein GI 109127928
UniProt ID F7BYH7
mRNA ID XM_001095880
Length 673
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEGNEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEFLKPEVKS
Refseq ID XP_001095880
Protein GI 109127926
UniProt ID F7BYH7
mRNA ID XM_001095880
Length 671
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEGNEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV

Gene Information

Entrez Gene ID
701195
Gene Name
protein kinase C, beta
Gene Symbol
PRKCB
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:Ensembl C cytoplasm
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0005634 IEA:Ensembl C nucleus
GO:0005886 IEA:Ensembl C plasma membrane
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0005246 IEA:Ensembl F calcium channel regulator activity
GO:0003682 IEA:Ensembl F chromatin binding
GO:0035403 IEA:Ensembl F histone kinase activity (H3-T6 specific)
GO:0030374 IEA:Ensembl F ligand-dependent nuclear receptor transcription coactivator activity
GO:0004697 IEA:UniProtKB-EC F protein kinase C activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0042113 IEA:Ensembl P B cell activation
GO:0050853 IEA:Ensembl P B cell receptor signaling pathway
GO:0006816 IEA:Ensembl P calcium ion transport
GO:0006874 IEA:Ensembl P cellular calcium ion homeostasis
GO:0071322 IEA:Ensembl P cellular response to carbohydrate stimulus
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0010829 IEA:Ensembl P negative regulation of glucose transport
GO:0050861 IEA:Ensembl P positive regulation of B cell receptor signaling pathway
GO:0043123 IEA:Ensembl P positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092 IEA:Ensembl P positive regulation of NF-kappaB transcription factor activity
GO:0045766 IEA:Ensembl P positive regulation of angiogenesis
GO:0030949 IEA:Ensembl P positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0006357 IEA:Ensembl P regulation of transcription from RNA polymerase II promoter

KEGG Pathway Links

KEGG Pathway ID Description
ko05143 African trypanosomiasis
mcc05143 African trypanosomiasis
ko04960 Aldosterone-regulated sodium reabsorption
mcc04960 Aldosterone-regulated sodium reabsorption
ko05146 Amoebiasis
mcc05146 Amoebiasis
ko05031 Amphetamine addiction
mcc05031 Amphetamine addiction
ko04020 Calcium signaling pathway
mcc04020 Calcium signaling pathway
ko04062 Chemokine signaling pathway
mcc04062 Chemokine signaling pathway
mcc04725 Cholinergic synapse
ko04713 Circadian entrainment
mcc04713 Circadian entrainment
ko04728 Dopaminergic synapse
mcc04728 Dopaminergic synapse
ko04961 Endocrine and other factor-regulated calcium reabsorption
mcc04961 Endocrine and other factor-regulated calcium reabsorption
ko04012 ErbB signaling pathway
mcc04012 ErbB signaling pathway
ko04666 Fc gamma R-mediated phagocytosis
mcc04666 Fc gamma R-mediated phagocytosis
ko04510 Focal adhesion
mcc04510 Focal adhesion
ko04727 GABAergic synapse
mcc04727 GABAergic synapse
ko04540 Gap junction
mcc04540 Gap junction
ko04971 Gastric acid secretion
mcc04971 Gastric acid secretion
ko05214 Glioma
mcc05214 Glioma
ko04724 Glutamatergic synapse
mcc04724 Glutamatergic synapse
mcc04066 HIF-1 signaling pathway
mcc05161 Hepatitis B
ko04750 Inflammatory mediator regulation of TRP channels
mcc04750 Inflammatory mediator regulation of TRP channels
mcc04911 Insulin secretion
ko05140 Leishmaniasis
mcc05140 Leishmaniasis
ko04670 Leukocyte transendothelial migration
mcc04670 Leukocyte transendothelial migration
ko04730 Long-term depression
mcc04730 Long-term depression
ko04720 Long-term potentiation
mcc04720 Long-term potentiation
ko04010 MAPK signaling pathway
mcc04010 MAPK signaling pathway
ko04916 Melanogenesis
mcc04916 Melanogenesis
ko05206 MicroRNAs in cancer
mcc05206 MicroRNAs in cancer
ko05032 Morphine addiction
mcc05032 Morphine addiction
ko04650 Natural killer cell mediated cytotoxicity
mcc04650 Natural killer cell mediated cytotoxicity
ko05223 Non-small cell lung cancer
mcc05223 Non-small cell lung cancer
ko04921 Oxytocin signaling pathway
mcc04921 Oxytocin signaling pathway
ko04972 Pancreatic secretion
mcc04972 Pancreatic secretion
mcc05200 Pathways in cancer
ko04070 Phosphatidylinositol signaling system
mcc04070 Phosphatidylinositol signaling system
ko05205 Proteoglycans in cancer
mcc05205 Proteoglycans in cancer
ko04015 Rap1 signaling pathway
mcc04015 Rap1 signaling pathway
mcc04014 Ras signaling pathway
ko04723 Retrograde endocannabinoid signaling
mcc04723 Retrograde endocannabinoid signaling
ko04970 Salivary secretion
mcc04970 Salivary secretion
mcc04726 Serotonergic synapse
mcc04919 Thyroid hormone signaling pathway
ko04918 Thyroid hormone synthesis
mcc04918 Thyroid hormone synthesis
ko04530 Tight junction
mcc04530 Tight junction
ko04370 VEGF signaling pathway
mcc04370 VEGF signaling pathway
ko04270 Vascular smooth muscle contraction
mcc04270 Vascular smooth muscle contraction
ko04310 Wnt signaling pathway
mcc04310 Wnt signaling pathway
ko04150 mTOR signaling pathway
mcc04150 mTOR signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR000961 AGC-kinase, C-terminal
IPR000008 C2 domain
IPR020454 Diacylglycerol/phorbol-ester binding
IPR014375 Protein kinase C, alpha/beta/gamma types
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR000719 Protein kinase domain
IPR017441 Protein kinase, ATP binding site
IPR017892 Protein kinase, C-terminal
IPR011009 Protein kinase-like domain
IPR008271 Serine/threonine-protein kinase, active site
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain

UniProt Annotations

Entry Information

Gene Name
protein kinase C, beta
Protein Entry
F7BYH7_MACMU
UniProt ID
F7BYH7
Species
Rhesus monkey

Comments

Comment Type Description
Catalytic Activity ATP + a protein = ADP + a phosphoprotein.
Similarity Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Similarity Contains 1 C2 domain.
Similarity Contains AGC-kinase C-terminal domain.
Similarity Contains protein kinase domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP014694 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109127928 RefSeq XP_001096447 673 protein kinase C, beta
109127926 RefSeq XP_001095880 671 protein kinase C, beta

Identical Sequences to LMP014694 proteins

Reference Database Accession Length Protein Name
GI:383873165 GenBank JAB31456.1 673 protein kinase C beta type isoform 2 [Callithrix jacchus]
GI:383873165 GenBank JAB31457.1 673 protein kinase C beta type isoform 2 [Callithrix jacchus]
GI:383873165 GenBank JAB31458.1 673 protein kinase C beta type isoform 2 [Callithrix jacchus]
GI:383873165 GenBank JAB31459.1 673 protein kinase C beta type isoform 2 [Callithrix jacchus]

Related Sequences to LMP014694 proteins

Reference Database Accession Length Protein Name