Gene/Proteome Database (LMPD)

LMPD ID
LMP014616
Gene ID
698200
Species
Macaca mulatta (Rhesus monkey)
Gene Name
phospholipase C-like 1
Gene Symbol
PLCL1
Alternate Names
inactive phospholipase C-like protein 1;
Chromosome
12
Map Location
chromosome:12
EC Number
3.1.4.11

Proteins

inactive phospholipase C-like protein 1
Refseq ID NP_001247783
Protein GI 386780810
UniProt ID H9ERR5
mRNA ID NM_001260854
Length 1095
Protein sequence is identical to GI:109100496 (mRNA isoform)
Refseq ID XP_001089483
Protein GI 109100496
UniProt ID H9ERR5
mRNA ID XM_001089483
Length 1095
MAEGAAGREDPAPPDAAGGEDDPRVGPDAAGDCVAAASGGRMRDRRSGVALPVTAGTPADSEAGLLEAARATPRRSSIIKDPSNQKCGGRKKTVSFSSMPSEKKISSANDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDMCLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYVRALKMGCRSIELDVSDGSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLLQQKVMVQQMKKVFGNKLYTEAPLPSESYLPSPEKLKRMIIVKGKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGEQKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWEICSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGIVPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFVALDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKVREYTMLRNIGLKTIDDIFKIAVHPLREAIDMRENMQNAIVSIKELCGLPPIASLKQCLLTLSSRLITSDNTPSVSLVMKDSFPYLEPLSAIPDVQKKMLAAYDLMIQESRFLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKLNKATESFAWNITVLKGQGDLLKNAKNEALENMKQIQLACLSCGLSKAPSSSAEAKSKRSLEAIEEKESSEENGKL

Gene Information

Entrez Gene ID
698200
Gene Name
phospholipase C-like 1
Gene Symbol
PLCL1
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005886 IEA:Ensembl C plasma membrane
GO:0005509 IEA:InterPro F calcium ion binding
GO:0070679 IEA:InterPro F inositol 1,4,5 trisphosphate binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0007214 IEA:Ensembl P gamma-aminobutyric acid signaling pathway
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:1900122 IEA:Ensembl P positive regulation of receptor binding
GO:0033135 IEA:Ensembl P regulation of peptidyl-serine phosphorylation
GO:0032228 IEA:Ensembl P regulation of synaptic transmission, GABAergic

KEGG Pathway Links

KEGG Pathway ID Description
ko04727 GABAergic synapse
mcc04727 GABAergic synapse

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR011992 EF-hand domain pair
IPR028382 Inactive phospholipase C-like protein 1
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
phospholipase C-like 1
Protein Entry
H9ERR5_MACMU
UniProt ID
H9ERR5
Species
Rhesus monkey

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PH domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PH domain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP014616 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109100496 RefSeq XP_001089483 1095 phospholipase C-like 1

Identical Sequences to LMP014616 proteins

Reference Database Accession Length Protein Name
GI:386780810 GenBank AFE65073.1 1095 inactive phospholipase C-like protein 1 [Macaca mulatta]
GI:386780810 GenBank AFE65074.1 1095 inactive phospholipase C-like protein 1 [Macaca mulatta]
GI:386780810 GenBank AFH32829.1 1095 inactive phospholipase C-like protein 1 [Macaca mulatta]
GI:386780810 RefSeq XP_005573898.1 1095 PREDICTED: inactive phospholipase C-like protein 1 isoform X1 [Macaca fascicularis]

Related Sequences to LMP014616 proteins

Reference Database Accession Length Protein Name