Gene/Proteome Database (LMPD)

LMPD ID
LMP014611
Gene ID
699569
Species
Macaca mulatta (Rhesus monkey)
Gene Name
phospholipase C, delta 4
Gene Symbol
PLCD4
Alternate Names
phospholipase C, delta 4;
Chromosome
12
Map Location
chromosome:12
EC Number
3.1.4.11

Proteins

Refseq ID XP_001091368
Protein GI 297264903
UniProt ID G7N8X4
mRNA ID XM_001091368
Length 799
MASLLQDRLTTDQDLLLMQEGMPMRKVRSKSWKKLRYFRLQNDGMTVWHARQARGSAKPSFSISDVETIRNGHDSELLRSLTEELPLEQGFTVVFHGRRSNLDLVANSVEEAQIWMRGLHLLVDLVTSMDHQERLDQWLSDWFQRGDKNQDGKMSFQEVQRLLHLMNVEMDQEYAFSLFQAADTSQSGTLEGEEFVEFYKALTKRAEVQELFESFSADGQKLTLLEFLDFLREEQKERDCTSELALELIDRYEPSDSGKLRHVLSMDGFLSYLCSKDGDIFNPACLPIYQDMTQPLNHYFICSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVWDGPSGEPVVYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETHCSWEQQQTMARHLTEILGEQLLSTTLDGVLPTQLPSPEELRRKILVKGKKLTLEEDLEYEEEEVEPGLEGEHESELALESQFETESEPEPQEQNLQIKDKKKVVTCPLFCPSICCQIVAQAPISKPGSLLLSQQKSKTILCPALSSLVIYLKSVSFRSFTHSKKHYHFYEISSFSETKAKRLIKEAGNEFVQHNTWQLSRVYPSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGGCGYVLKPDFLRDNQSSFHPERPISPFKAQTLLIQVISGQQLPKLNKTKEGSIVDPLVKVQIFGVRLDTARQETNYVENNGFNPYWGQTLCFRVLVPELAMLRFVVMDYDWKSRNDFIGQYTLPWSCMQQGYRHIHLLSKDGISLCPASIFVYICIREGLEGDES

Gene Information

Entrez Gene ID
699569
Gene Name
phospholipase C, delta 4
Gene Symbol
PLCD4
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005622 IEA:InterPro C intracellular
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0007340 IEA:InterPro P acrosome reaction
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:0046488 IEA:InterPro P phosphatidylinositol metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ko04020 Calcium signaling pathway
mcc04020 Calcium signaling pathway
ko00562 Inositol phosphate metabolism
mcc00562 Inositol phosphate metabolism
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
mcc_M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
mcc01100 Metabolic pathways
ko04070 Phosphatidylinositol signaling system
mcc04070 Phosphatidylinositol signaling system
mcc04919 Thyroid hormone signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR028387 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
IPR000008 C2 domain
IPR018247 EF-Hand 1, calcium-binding site
IPR002048 EF-hand domain
IPR011992 EF-hand domain pair
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
phospholipase C, delta 4
Protein Entry
G7N8X4_MACMU
UniProt ID
G7N8X4
Species
Rhesus monkey

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PH domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains 3 EF-hand domains.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PH domain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP014611 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
297264903 RefSeq XP_001091368 799 phospholipase C, delta 4

Identical Sequences to LMP014611 proteins

Reference Database Accession Length Protein Name
GI:297264903 GenBank EHH21674.1 799 hypothetical protein EGK_04797 [Macaca mulatta]
GI:297264903 RefSeq XP_005574345.1 799 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [Macaca fascicularis]
GI:297264903 RefSeq XP_005574346.1 799 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X2 [Macaca fascicularis]

Related Sequences to LMP014611 proteins

Reference Database Accession Length Protein Name
GI:297264903 DBBJ BAE01262.1 799 unnamed protein product [Macaca fascicularis]