Gene/Proteome Database (LMPD)

LMPD ID
LMP014592
Gene ID
704520
Species
Macaca mulatta (Rhesus monkey)
Gene Name
phospholipase A2, group IIA (platelets, synovial fluid)
Gene Symbol
PLA2G2A
Alternate Names
phospholipase A2, group IIA (platelets, synovial fluid);
Chromosome
1
Map Location
chromosome:1

Proteins

Refseq ID XP_001094731
Protein GI 108998704
UniProt ID F7EHU8
mRNA ID XM_001094731
Length 144
MKTLLLLAVIMIFGLLQAHGNLVDFRRMIKLKTGKEAALSYGFYGCHCGVGGKGAPKDATDRCCVVHDCCYKRLEKRGCGTKFLSYKFSNKGSTITCAKQDSCRSQLCECDKAAAYCFARNKSTYNKNYQYYSNKFCRGSTPRC

Gene Information

Entrez Gene ID
704520
Gene Name
phospholipase A2, group IIA (platelets, synovial fluid)
Gene Symbol
PLA2G2A
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:Ensembl C endoplasmic reticulum
GO:0005615 IEA:Ensembl C extracellular space
GO:0005739 IEA:Ensembl C mitochondrion
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004623 IEA:Ensembl F phospholipase A2 activity
GO:0005543 IEA:Ensembl F phospholipid binding
GO:0016042 IEA:InterPro P lipid catabolic process
GO:0050680 IEA:Ensembl P negative regulation of epithelial cell proliferation
GO:0046473 IEA:Ensembl P phosphatidic acid metabolic process
GO:0035019 IEA:Ensembl P somatic stem cell maintenance

KEGG Pathway Links

KEGG Pathway ID Description
ko00590 Arachidonic acid metabolism
mcc00590 Arachidonic acid metabolism
ko00565 Ether lipid metabolism
mcc00565 Ether lipid metabolism
ko04975 Fat digestion and absorption
mcc04975 Fat digestion and absorption
ko00564 Glycerophospholipid metabolism
mcc00564 Glycerophospholipid metabolism
ko00591 Linoleic acid metabolism
mcc00591 Linoleic acid metabolism
mcc01100 Metabolic pathways
ko04972 Pancreatic secretion
mcc04972 Pancreatic secretion
mcc04014 Ras signaling pathway
ko04270 Vascular smooth muscle contraction
mcc04270 Vascular smooth muscle contraction
ko00592 alpha-Linolenic acid metabolism
mcc00592 alpha-Linolenic acid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR001211 Phospholipase A2
IPR016090 Phospholipase A2 domain
IPR013090 Phospholipase A2, active site

UniProt Annotations

Entry Information

Gene Name
phospholipase A2, group IIA (platelets, synovial fluid)
Protein Entry
F7EHU8_MACMU
UniProt ID
F7EHU8
Species
Rhesus monkey

Comments

Comment Type Description
Catalytic Activity Phosphatidylcholine + H(2)O = 1- acylglycerophosphocholine + a carboxylate.
Cofactor Note=Binds 1 calcium ion per subunit. ;
Similarity Belongs to the phospholipase A2 family.
Subcellular Location Secreted

Identical and Related Proteins

Unique RefSeq proteins for LMP014592 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
108998704 RefSeq XP_001094731 144 phospholipase A2, group IIA (platelets, synovial fluid)

Identical Sequences to LMP014592 proteins

Reference Database Accession Length Protein Name
GI:108998704 GenBank EHH14401.1 144 hypothetical protein EGK_00322 [Macaca mulatta]

Related Sequences to LMP014592 proteins

Reference Database Accession Length Protein Name
GI:108998704 GenBank EHH49604.1 144 hypothetical protein EGM_00293 [Macaca fascicularis]
GI:108998704 RefSeq XP_005544624.1 144 PREDICTED: phospholipase A2, membrane associated [Macaca fascicularis]
GI:108998704 RefSeq XP_009199061.1 144 PREDICTED: phospholipase A2, membrane associated [Papio anubis]