Gene/Proteome Database (LMPD)

LMPD ID
LMP014567
Gene ID
698996
Species
Macaca mulatta (Rhesus monkey)
Gene Name
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Gene Symbol
PIK3R1
Alternate Names
phosphatidylinositol 3-kinase regulatory subunit alpha; phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha);
Chromosome
6
Map Location
chromosome:6

Proteins

phosphatidylinositol 3-kinase regulatory subunit alpha
Refseq ID NP_001248126
Protein GI 386781373
UniProt ID F7BZL6
mRNA ID NM_001261197
Length 724
Protein sequence is identical to GI:109077444 (mRNA isoform)
Refseq ID XP_001089423
Protein GI 109077444
UniProt ID F7BZL6
mRNA ID XM_001089423
Length 724
MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAEQFAPPDVAPPLLIKLVEAIEKKGLECSTLYRTQSSGNLAELRQLLDCDTASVDLEMIDVHILADAFKRYLLDLPNPVIPAAVYSEMISLAQEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR

Gene Information

Entrez Gene ID
698996
Gene Name
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Gene Symbol
PIK3R1
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005911 IEA:Ensembl C cell-cell junction
GO:0016020 IEA:Ensembl C membrane
GO:0005942 IEA:InterPro C phosphatidylinositol 3-kinase complex
GO:0043559 IEA:Ensembl F insulin binding
GO:0016301 IEA:UniProtKB-KW F kinase activity
GO:0035014 IEA:InterPro F phosphatidylinositol 3-kinase regulator activity
GO:0030183 IEA:Ensembl P B cell differentiation
GO:0051531 IEA:Ensembl P NFAT protein import into nucleus
GO:0034644 IEA:Ensembl P cellular response to UV
GO:0008625 IEA:Ensembl P extrinsic apoptotic signaling pathway via death domain receptors
GO:0060396 IEA:Ensembl P growth hormone receptor signaling pathway
GO:0048009 IEA:Ensembl P insulin-like growth factor receptor signaling pathway
GO:0008630 IEA:Ensembl P intrinsic apoptotic signaling pathway in response to DNA damage
GO:0043066 IEA:Ensembl P negative regulation of apoptotic process
GO:0001953 IEA:Ensembl P negative regulation of cell-matrix adhesion
GO:0045671 IEA:Ensembl P negative regulation of osteoclast differentiation
GO:0014065 IEA:Ensembl P phosphatidylinositol 3-kinase signaling
GO:0030335 IEA:Ensembl P positive regulation of cell migration
GO:0045944 IEA:Ensembl P positive regulation of transcription from RNA polymerase II promoter
GO:0032760 IEA:Ensembl P positive regulation of tumor necrosis factor production
GO:0006468 IEA:Ensembl P protein phosphorylation

KEGG Pathway Links

KEGG Pathway ID Description
ko04152 AMPK signaling pathway
mcc04152 AMPK signaling pathway
ko05221 Acute myeloid leukemia
mcc05221 Acute myeloid leukemia
ko04261 Adrenergic signaling in cardiomyocytes
mcc04261 Adrenergic signaling in cardiomyocytes
ko04960 Aldosterone-regulated sodium reabsorption
mcc04960 Aldosterone-regulated sodium reabsorption
ko05146 Amoebiasis
mcc05146 Amoebiasis
ko04210 Apoptosis
mcc04210 Apoptosis
ko04662 B cell receptor signaling pathway
mcc04662 B cell receptor signaling pathway
ko05100 Bacterial invasion of epithelial cells
mcc05100 Bacterial invasion of epithelial cells
ko04973 Carbohydrate digestion and absorption
mcc04973 Carbohydrate digestion and absorption
ko05142 Chagas disease (American trypanosomiasis)
mcc05142 Chagas disease (American trypanosomiasis)
ko04062 Chemokine signaling pathway
mcc04062 Chemokine signaling pathway
mcc04725 Cholinergic synapse
ko05220 Chronic myeloid leukemia
mcc05220 Chronic myeloid leukemia
ko05210 Colorectal cancer
mcc05210 Colorectal cancer
ko05213 Endometrial cancer
mcc05213 Endometrial cancer
ko05169 Epstein-Barr virus infection
mcc05169 Epstein-Barr virus infection
ko04012 ErbB signaling pathway
mcc04012 ErbB signaling pathway
ko04915 Estrogen signaling pathway
mcc04915 Estrogen signaling pathway
ko04664 Fc epsilon RI signaling pathway
mcc04664 Fc epsilon RI signaling pathway
ko04666 Fc gamma R-mediated phagocytosis
mcc04666 Fc gamma R-mediated phagocytosis
ko04510 Focal adhesion
mcc04510 Focal adhesion
mcc04068 FoxO signaling pathway
ko05214 Glioma
mcc05214 Glioma
mcc04066 HIF-1 signaling pathway
ko05166 HTLV-I infection
mcc05166 HTLV-I infection
mcc05161 Hepatitis B
ko05160 Hepatitis C
mcc05160 Hepatitis C
ko04750 Inflammatory mediator regulation of TRP channels
mcc04750 Inflammatory mediator regulation of TRP channels
ko05164 Influenza A
mcc05164 Influenza A
ko04910 Insulin signaling pathway
mcc04910 Insulin signaling pathway
ko04630 Jak-STAT signaling pathway
mcc04630 Jak-STAT signaling pathway
ko04670 Leukocyte transendothelial migration
mcc04670 Leukocyte transendothelial migration
ko05162 Measles
mcc05162 Measles
ko05218 Melanoma
mcc05218 Melanoma
ko04650 Natural killer cell mediated cytotoxicity
mcc04650 Natural killer cell mediated cytotoxicity
ko04722 Neurotrophin signaling pathway
mcc04722 Neurotrophin signaling pathway
ko04932 Non-alcoholic fatty liver disease (NAFLD)
mcc04932 Non-alcoholic fatty liver disease (NAFLD)
ko05223 Non-small cell lung cancer
mcc05223 Non-small cell lung cancer
ko04380 Osteoclast differentiation
mcc04380 Osteoclast differentiation
ko04921 Oxytocin signaling pathway
mcc04921 Oxytocin signaling pathway
ko04151 PI3K-Akt signaling pathway
mcc04151 PI3K-Akt signaling pathway
ko05212 Pancreatic cancer
mcc05212 Pancreatic cancer
mcc05200 Pathways in cancer
ko04070 Phosphatidylinositol signaling system
mcc04070 Phosphatidylinositol signaling system
mcc04611 Platelet activation
ko04914 Progesterone-mediated oocyte maturation
mcc04914 Progesterone-mediated oocyte maturation
ko04917 Prolactin signaling pathway
mcc04917 Prolactin signaling pathway
ko05215 Prostate cancer
mcc05215 Prostate cancer
ko05205 Proteoglycans in cancer
mcc05205 Proteoglycans in cancer
ko04015 Rap1 signaling pathway
mcc04015 Rap1 signaling pathway
mcc04014 Ras signaling pathway
ko04810 Regulation of actin cytoskeleton
mcc04810 Regulation of actin cytoskeleton
ko05211 Renal cell carcinoma
mcc05211 Renal cell carcinoma
ko04550 Signaling pathways regulating pluripotency of stem cells
mcc04550 Signaling pathways regulating pluripotency of stem cells
ko05222 Small cell lung cancer
mcc05222 Small cell lung cancer
ko04660 T cell receptor signaling pathway
mcc04660 T cell receptor signaling pathway
ko04668 TNF signaling pathway
mcc04668 TNF signaling pathway
mcc04919 Thyroid hormone signaling pathway
ko04620 Toll-like receptor signaling pathway
mcc04620 Toll-like receptor signaling pathway
ko05145 Toxoplasmosis
mcc05145 Toxoplasmosis
ko04930 Type II diabetes mellitus
mcc04930 Type II diabetes mellitus
ko04370 VEGF signaling pathway
mcc04370 VEGF signaling pathway
ko05203 Viral carcinogenesis
mcc05203 Viral carcinogenesis
ko04024 cAMP signaling pathway
mcc04024 cAMP signaling pathway
ko04022 cGMP-PKG signaling pathway
mcc04022 cGMP-PKG signaling pathway
ko04150 mTOR signaling pathway
mcc04150 mTOR signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR001720 PI3 kinase, P85 regulatory subunit
IPR008936 Rho GTPase activation protein
IPR000198 Rho GTPase-activating protein domain
IPR000980 SH2 domain
IPR001452 SH3_domain
IPR011511 Variant SH3 domain

UniProt Annotations

Entry Information

Gene Name
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Protein Entry
F7BZL6_MACMU
UniProt ID
F7BZL6
Species
Rhesus monkey

Identical and Related Proteins

Unique RefSeq proteins for LMP014567 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109077444 RefSeq XP_001089423 724 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Identical Sequences to LMP014567 proteins

Reference Database Accession Length Protein Name
GI:386781373 GenBank AFI37456.1 724 phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1 [Macaca mulatta]
GI:386781373 RefSeq XP_009206815.1 724 PREDICTED: phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [Papio anubis]
GI:386781373 RefSeq XP_009206817.1 724 PREDICTED: phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [Papio anubis]
GI:386781373 RefSeq XP_009206818.1 724 PREDICTED: phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [Papio anubis]

Related Sequences to LMP014567 proteins

Reference Database Accession Length Protein Name