Gene/Proteome Database (LMPD)

LMPD ID
LMP014419
Gene ID
699235
Species
Macaca mulatta (Rhesus monkey)
Gene Name
NPC1 (Niemann-Pick disease, type C1, gene)-like 1
Gene Symbol
NPC1L1
Alternate Names
Niemann-Pick C1-like protein 1; Niemann-Pick C1-like 1 protein;
Chromosome
3
Map Location
chromosome:3

Proteins

Niemann-Pick C1-like protein 1 precursor
Refseq ID NP_001071157
Protein GI 117956369
UniProt ID A0MJA5
mRNA ID NM_001077689
Length 1332
MAEAGLRGWLLWALLLHLAQSEPYTPIHQPGYCAFYDECGKNPELSGGLMTLSNVSCLSNTPARNITGDHLILLQRICPRLYTGPNTQACCSAKQLVSLEASLSITKALLTRCPACSDNFVSLHCHNTCSPNQSLFINVTRVAQLGAGQLPAVVAYEAFYQHSFAEQSYDSCSRVHIPAAATLAVGSMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQAVGSGIQPLNEGVARCNESQGDDAVACSCQDCAASCPAIAHPQALDSTFRLGRMPGGLVLIIILCSVFTVVAILLVGLRVAPTRDKSKTVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTILVLSVIPVVVLAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSYRYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRNISLQHICYAPLNPDNTSLSDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWRDHFLYCANAPLTFKDGTALALSCMADYGAPVFPFLAVGGYKGKDYSEAEALIMTFSLNNYPAGDPRLAQAQLWEEAFLEEMRAFQRRTAGKFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLIILQVVPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAVVLDFLLQMSAFVALLSLDSKRQEASRLDVCCCVKPRELPLPGQGEGFLLGLFRKAYVPFLLHWITRGVVLLLFLALFGVSLYYMCHISVGLDQELALPKDSYLLDYFLFLNRYFETGAPVYFVTTSGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSSCCRLYISGPNKDQFCPSTVNSLNCLKNCLSITMGSVRPSVEQFYKYLPWFLNDRPNIKCPKGGLGAYSTSVNLTSDGQVLASRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTVTNVFYEQYLTILPEGLFMLSLCLVPTFAVCCLLLGLDLRSGLLNLLSIIMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTRLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDINPALALEQKLAEEAAAAAIAASYPNHPSRVSTADNIYVNHSFEGSIKGAGAVSNFLPNNGRQF
sig_peptide: 1..21 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2350 peptide sequence: MAEAGLRGWLLWALLLHLAQS

Gene Information

Entrez Gene ID
699235
Gene Name
NPC1 (Niemann-Pick disease, type C1, gene)-like 1
Gene Symbol
NPC1L1
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:InterPro C integral component of membrane
GO:0008158 IEA:InterPro F hedgehog receptor activity
GO:0030301 IEA:InterPro P cholesterol transport

KEGG Pathway Links

KEGG Pathway ID Description
ko04975 Fat digestion and absorption
mcc04975 Fat digestion and absorption

Domain Information

InterPro Annotations

Accession Description
IPR004765 Niemann-Pick C type protein
IPR003392 Patched
IPR000731 Sterol-sensing domain

UniProt Annotations

Entry Information

Gene Name
NPC1 (Niemann-Pick disease, type C1, gene)-like 1
Protein Entry
A0MJA5_MACMU
UniProt ID
A0MJA5
Species
Rhesus monkey

Identical and Related Proteins

Unique RefSeq proteins for LMP014419 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
117956369 RefSeq NP_001071157 1332 Niemann-Pick C1-like protein 1 precursor

Identical Sequences to LMP014419 proteins

Reference Database Accession Length Protein Name
GI:117956369 GenBank AED75201.1 1332 Sequence 8 from patent US 7910698
GI:117956369 GenBank AED75202.1 1332 Sequence 10 from patent US 7910698
GI:117956369 GenBank AFO16158.1 1332 Sequence 8 from patent US 8212016
GI:117956369 GenBank AFO16159.1 1332 Sequence 10 from patent US 8212016

Related Sequences to LMP014419 proteins

Reference Database Accession Length Protein Name
GI:117956369 GenBank ABK32535.1 1332 Niemann-Pick C1-like 1 protein [Macaca mulatta]
GI:117956369 GenBank ABK32536.1 1332 Niemann-Pick C1-like 1 protein [Macaca fascicularis]