Gene/Proteome Database (LMPD)

LMPD ID
LMP014300
Gene ID
695240
Species
Macaca mulatta (Rhesus monkey)
Gene Name
lipase A, lysosomal acid, cholesterol esterase
Gene Symbol
LIPA
Alternate Names
lysosomal acid lipase/cholesteryl ester hydrolase;
Chromosome
9
Map Location
chromosome:9

Proteins

lysosomal acid lipase/cholesteryl ester hydrolase precursor
Refseq ID NP_001253275
Protein GI 388453533
UniProt ID F7EC56
mRNA ID NM_001266346
Length 399
Protein sequence is identical to GI:109089860 (mRNA isoform)
sig_peptide: 1..23 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2591 peptide sequence: MKMRFLGLVVCLVLWTLHSEASG
Refseq ID XP_001085504
Protein GI 109089860
UniProt ID F7EC56
mRNA ID XM_001085632
Length 399
MKMRFLGLVVCLVLWTLHSEASGGKLTAVNPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALAPVVSVDFCTSPMAKLGRLPDLLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDINILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMKKYQ
sig_peptide: 1..23 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2591 peptide sequence: MKMRFLGLVVCLVLWTLHSEASG
Refseq ID XP_001085632
Protein GI 109089862
UniProt ID F7EC56
mRNA ID XM_001085632
Length 399
Protein sequence is identical to GI:109089860 (mRNA isoform)
sig_peptide: 1..23 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2591 peptide sequence: MKMRFLGLVVCLVLWTLHSEASG
Refseq ID XP_001085160
Protein GI 297301446
UniProt ID F7EC56
mRNA ID XM_001085632
Length 409
MSKSQVEGKRMKMRFLGLVVCLVLWTLHSEASGGKLTAVNPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALAPVVSVDFCTSPMAKLGRLPDLLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDINILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMKKYQ
sig_peptide: 1..23 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2591 peptide sequence: MKMRFLGLVVCLVLWTLHSEASG

Gene Information

Entrez Gene ID
695240
Gene Name
lipase A, lysosomal acid, cholesterol esterase
Gene Symbol
LIPA
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0016298 IEA:Ensembl F lipase activity
GO:0004771 IEA:Ensembl F sterol esterase activity
GO:0000902 IEA:Ensembl P cell morphogenesis
GO:0008283 IEA:Ensembl P cell proliferation
GO:0001816 IEA:Ensembl P cytokine production
GO:0048873 IEA:Ensembl P homeostasis of number of cells within a tissue
GO:0006954 IEA:Ensembl P inflammatory response
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:0030324 IEA:Ensembl P lung development
GO:0048771 IEA:Ensembl P tissue remodeling

KEGG Pathway Links

KEGG Pathway ID Description
ko04142 Lysosome
mcc04142 Lysosome
ko00100 Steroid biosynthesis
mcc00100 Steroid biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR000073 Alpha/beta hydrolase fold-1
IPR025483 Lipase, eukaryotic
IPR006693 Partial AB-hydrolase lipase domain

UniProt Annotations

Entry Information

Gene Name
lipase A, lysosomal acid, cholesterol esterase
Protein Entry
F7EC56_MACMU
UniProt ID
F7EC56
Species
Rhesus monkey

Identical and Related Proteins

Unique RefSeq proteins for LMP014300 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
297301446 RefSeq XP_001085160 409 lipase A, lysosomal acid, cholesterol esterase
109089860 RefSeq XP_001085504 399 lipase A, lysosomal acid, cholesterol esterase

Identical Sequences to LMP014300 proteins

Reference Database Accession Length Protein Name
GI:388453533 GenBank EHH64862.1 399 hypothetical protein EGM_18189 [Macaca fascicularis]
GI:388453533 GenBank AFE78232.1 399 lysosomal acid lipase/cholesteryl ester hydrolase precursor [Macaca mulatta]
GI:388453533 GenBank AFH32377.1 399 lysosomal acid lipase/cholesteryl ester hydrolase precursor [Macaca mulatta]
GI:388453533 GenBank AFI37114.1 399 lysosomal acid lipase/cholesteryl ester hydrolase precursor [Macaca mulatta]

Related Sequences to LMP014300 proteins

Reference Database Accession Length Protein Name
GI:388453533 GenBank EHH19208.1 399 hypothetical protein EGK_19878 [Macaca mulatta]
GI:388453533 SwissProt Q4R4S5.1 399 RecName: Full=Lysosomal acid lipase/cholesteryl ester hydrolase; Short=Acid cholesteryl ester hydrolase; Short=LAL; AltName: Full=Cholesteryl esterase; AltName: Full=Lipase A; AltName: Full=Sterol esterase; Flags: Precursor [Macaca fascicularis]