Gene/Proteome Database (LMPD)

LMPD ID
LMP014279
Gene ID
708714
Species
Macaca mulatta (Rhesus monkey)
Gene Name
inositol 1,4,5-trisphosphate receptor, type 2
Gene Symbol
ITPR2
Alternate Names
inositol 1,4,5-trisphosphate receptor, type 2; inositol 1,4,5-triphosphate receptor, type 2;
Chromosome
11
Map Location
chromosome:11

Proteins

Refseq ID XP_001102937
Protein GI 109095988
UniProt ID F7DGC2
mRNA ID XM_001102937
Length 2700
MTDKMSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLANPPKKFRDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENKKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNAGQPLHASNIELLDNPGCKEVNAVNCNTSWKITLFMKYSSYREDVLKGGDVVRLFHAEQEKFLTCDEYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVRDDHPTSKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTDEERPVMLKIGTCQTKEDKEAFAIVSVPLSEVRDLDFANDANKVLATTVKKLENGTITQNERRFVTKLLEDLIFFVADVPNNGQEVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYMLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPGNADILIQTKVVSMQADNPMESSILSDDIDDEEVWLYWIDSNREPHGKAIRHLAQEAKEGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPMSVPDVPPSIHPSKQGSPAEHEDVTVMDTKLKIIEILQFILSVRLDYRISYMLSIYKKEFGEDNDNAETSASGSPDTLLPSAIVPDIDEIAAQAETMFAGRKEKNPVQLDDEGGRTFLRVLIHLIMHDYPPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSSNYENGEIGESQVKGGEEPIEESNILSPVQDGTKKPQIDSNKSNNYRIVKEILIRLSKLCVQNKKCRIQHQRLLKNMGAHSVVLDLLQIPYEKNDEKMNEVMNLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLHMMCSERDRGDESGPLAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRKHADLFLEKCVTESIMNIVSGFFNSPFSDNSTSLQTHQPVFIQLLQSAFRIYNCTWPNPSQKASVESCIRTLAEVAKNRGIAIPVDLDGQVNTLFMKSHSNMVQRAAMGWRLSARSGPRFKEALGGPSWDYRNIIEKLQDVVASLEHQFSPMMQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINHTKKLMEKEEKLCIKILQTLREMLEKKDSFVEEGNTLRKILLNRYFKGDYSIGMNGHLSGAYSKTAQVGGSFSGQDSDKMGISMSDIQCLLDKEGASELVIDVIVNTKNDRIFSEGIFLGIALLEGGNTQTQYSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGSKKRDDDNELMTSGPRMRVRDSTLHLKEGMKGQLTEASSATSKAYCVYRREMDPEIDIMCTGPEAGNTEEKSAEEVTMSPAIAIMQPILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLGKYRMDLVLQLKNNASKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQGLECDHGDDEGGDDGVSPKDVGHNIYILAHQLARHNKLLQQMLKPGSDPDEGDEALKYYANHTAQIEIVRHDRTMEQIVFPVPNICEYLTRESKCRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPLFSVLLWIAVAICTSMLFFFSKPVGIRPFLVSIMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGSHQVPTMTLTTMMEACAKENCSPTIPASNTADEEYEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDEPLFAARVVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGSNTPHVNHHMPPH

Gene Information

Entrez Gene ID
708714
Gene Name
inositol 1,4,5-trisphosphate receptor, type 2
Gene Symbol
ITPR2
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:InterPro C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005220 IEA:InterPro F inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

KEGG Pathway Links

KEGG Pathway ID Description
ko05010 Alzheimer's disease
mcc05010 Alzheimer's disease
ko04020 Calcium signaling pathway
mcc04020 Calcium signaling pathway
mcc04725 Cholinergic synapse
ko04728 Dopaminergic synapse
mcc04728 Dopaminergic synapse
ko04915 Estrogen signaling pathway
mcc04915 Estrogen signaling pathway
ko04540 Gap junction
mcc04540 Gap junction
ko04971 Gastric acid secretion
mcc04971 Gastric acid secretion
ko04724 Glutamatergic synapse
mcc04724 Glutamatergic synapse
ko04912 GnRH signaling pathway
mcc04912 GnRH signaling pathway
ko04750 Inflammatory mediator regulation of TRP channels
mcc04750 Inflammatory mediator regulation of TRP channels
ko04730 Long-term depression
mcc04730 Long-term depression
ko04720 Long-term potentiation
mcc04720 Long-term potentiation
ko04114 Oocyte meiosis
mcc04114 Oocyte meiosis
ko04921 Oxytocin signaling pathway
mcc04921 Oxytocin signaling pathway
ko04972 Pancreatic secretion
mcc04972 Pancreatic secretion
ko04070 Phosphatidylinositol signaling system
mcc04070 Phosphatidylinositol signaling system
mcc04611 Platelet activation
ko05205 Proteoglycans in cancer
mcc05205 Proteoglycans in cancer
ko04723 Retrograde endocannabinoid signaling
mcc04723 Retrograde endocannabinoid signaling
ko04970 Salivary secretion
mcc04970 Salivary secretion
mcc04726 Serotonergic synapse
ko04918 Thyroid hormone synthesis
mcc04918 Thyroid hormone synthesis
ko04270 Vascular smooth muscle contraction
mcc04270 Vascular smooth muscle contraction
ko04022 cGMP-PKG signaling pathway
mcc04022 cGMP-PKG signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR016024 Armadillo-type fold
IPR000493 Inositol 1,4,5-trisphosphate-binding protein receptor
IPR014821 Inositol 1,4,5-trisphosphate/ryanodine receptor
IPR005821 Ion transport domain
IPR016093 MIR_motif
IPR000699 RIH (RyR and IP3R Homology) domain
IPR013662 RyR/IP3R Homology associated domain
IPR015925 Ryanodine receptor-related

UniProt Annotations

Entry Information

Gene Name
inositol 1,4,5-trisphosphate receptor, type 2
Protein Entry
F7DGC2_MACMU
UniProt ID
F7DGC2
Species
Rhesus monkey

Identical and Related Proteins

Unique RefSeq proteins for LMP014279 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109095988 RefSeq XP_001102937 2700 inositol 1,4,5-trisphosphate receptor, type 2

Identical Sequences to LMP014279 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP014279 proteins

Reference Database Accession Length Protein Name
GI:109095988 GenBank AFE78150.1 2700 inositol 1,4,5-trisphosphate receptor type 2 [Macaca mulatta]
GI:109095988 GenBank AFH32304.1 2700 inositol 1,4,5-trisphosphate receptor type 2 [Macaca mulatta]
GI:109095988 RefSeq XP_005570479.1 2700 PREDICTED: inositol 1,4,5-trisphosphate receptor type 2 isoform X2 [Macaca fascicularis]
GI:109095988 RefSeq XP_007966183.1 2700 PREDICTED: inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [Chlorocebus sabaeus]