Gene/Proteome Database (LMPD)

LMPD ID
LMP013781
Gene ID
707926
Species
Macaca mulatta (Rhesus monkey)
Gene Name
arachidonate 5-lipoxygenase
Gene Symbol
ALOX5
Alternate Names
arachidonate 5-lipoxygenase;
Chromosome
9
Map Location
chromosome:9

Proteins

Refseq ID XP_002805673
Protein GI 297300873
UniProt ID F6YPK7
mRNA ID XM_001102354
Length 617
MPSYTVTVATGSQWFAGTDDYIYLSLLGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELGEIQLVKIEKRKYWLHDDWYLKYITLKTPQGDYIEFPCYRWITGDGEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWSPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKFPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLSQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRYTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRMFTAEVVGIYYESDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQLFLGMYPEEHFIEKPVKAAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI
Refseq ID XP_001102354
Protein GI 109088880
UniProt ID F6YPK7
mRNA ID XM_001102354
Length 674
MPSYTVTVATGSQWFAGTDDYIYLSLLGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELGEIQLVKIEKRKYWLHDDWYLKYITLKTPQGDYIEFPCYRWITGDGEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWSPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKFPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLSQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRYTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRMFTAEVVGIYYESDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKAAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI

Gene Information

Entrez Gene ID
707926
Gene Name
arachidonate 5-lipoxygenase
Gene Symbol
ALOX5
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IEA:Ensembl C cytosol
GO:0005615 IEA:Ensembl C extracellular space
GO:0005641 IEA:Ensembl C nuclear envelope lumen
GO:0016363 IEA:Ensembl C nuclear matrix
GO:0031965 IEA:Ensembl C nuclear membrane
GO:0004051 IEA:Ensembl F arachidonate 5-lipoxygenase activity
GO:0005506 IEA:Ensembl F iron ion binding
GO:0019370 IEA:Ensembl P leukotriene biosynthetic process
GO:0002540 IEA:Ensembl P leukotriene production involved in inflammatory response

KEGG Pathway Links

KEGG Pathway ID Description
ko00590 Arachidonic acid metabolism
mcc00590 Arachidonic acid metabolism
mcc01100 Metabolic pathways
ko04913 Ovarian steroidogenesis
mcc04913 Ovarian steroidogenesis
mcc04726 Serotonergic synapse
ko05145 Toxoplasmosis
mcc05145 Toxoplasmosis

Domain Information

InterPro Annotations

Accession Description
IPR008976 Lipase/lipooxygenase, PLAT/LH2
IPR000907 Lipoxygenase
IPR013819 Lipoxygenase, C-terminal
IPR020834 Lipoxygenase, conserved site
IPR020833 Lipoxygenase, iron binding site
IPR001885 Lipoxygenase, mammalian
IPR001024 PLAT/LH2 domain

UniProt Annotations

Entry Information

Gene Name
arachidonate 5-lipoxygenase
Protein Entry
F6YPK7_MACMU
UniProt ID
F6YPK7
Species
Rhesus monkey

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Cofactor Note=Iron. ;
Similarity Belongs to the lipoxygenase family.
Similarity Contains PLAT domain.
Similarity Contains lipoxygenase domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP013781 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109088880 RefSeq XP_001102354 674 arachidonate 5-lipoxygenase
297300873 RefSeq XP_002805673 617 arachidonate 5-lipoxygenase

Identical Sequences to LMP013781 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP013781 proteins

Reference Database Accession Length Protein Name
GI:297300873 DBBJ BAJ20691.1 617 arachidonate 5-lipoxygenase, partial [synthetic construct]
GI:297300873 GenBank ADR30799.1 617 arachidonic 5-lipoxygenase delta-13 isoform [Homo sapiens]
GI:297300873 RefSeq XP_003903645.1 674 PREDICTED: arachidonate 5-lipoxygenase [Papio anubis]
GI:297300873 SwissProt P09917.2 674 RecName: Full=Arachidonate 5-lipoxygenase; Short=5-LO; Short=5-lipoxygenase [Homo sapiens]