Gene/Proteome Database (LMPD)

LMPD ID
LMP013779
Gene ID
709212
Species
Macaca mulatta (Rhesus monkey)
Gene Name
arachidonate 15-lipoxygenase
Gene Symbol
ALOX15
Alternate Names
arachidonate 15-lipoxygenase;
Chromosome
16
Map Location
chromosome:16

Proteins

Refseq ID XP_001094627
Protein GI 109112842
UniProt ID F7EPQ4
mRNA ID XM_001094627
Length 662
MGLYRIRLSTGASLHAGSKNQVQLWLVGQHGEAVLGKRLWPARGKETEVKVEVPEYLGPLLFVKLRKRHLLQDDAWFCNWISVQGPGDGDEVRFPCYRWVEGDGVLSLPEGTGRTVGEDPQGLFQKHREEELEERRKLYRWGNWKDGLILNVAGTKLSDLPVDERFLEDKRVDFEASLAKGLADLAIKDSLNVLTRWKDLDDFKRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPMLLRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEADFSLLDGIKANVILCSQQYLAAPLVMLKLQPDGKLLPMVIQLQLPSAGSPPPPLFLPTDPPMVWLLAKCWVRSSDFQLHELQSHLLRGHLMAEVIAVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGVFDQVVSTGGGGHVELLRRAGGFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIFRYVEGIVSLHYKTDVAVKDDPELQTWCREITEIGLQGGQDRGFPVSLQSRDQVCHFVTMCIFTCTGQHSSVHLGQLDWYTWVPNAPCTMRLPPPTTKDATLETVMATLPNFHQASLQMSITWQLGRRQPIMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIENRNAKLDMPYEYLRPSLVENSVAI
Refseq ID XP_002800298
Protein GI 297271648
UniProt ID F7EPQ4
mRNA ID XM_001094627
Length 623
MGLYRIRLSTGASLHAGSKNQVQLWLVGQHGEAVLGKRLWPARGKGPGDGDEVRFPCYRWVEGDGVLSLPEGTGRTVGEDPQGLFQKHREEELEERRKLYRWGNWKDGLILNVAGTKLSDLPVDERFLEDKRVDFEASLAKGLADLAIKDSLNVLTRWKDLDDFKRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPMLLRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEADFSLLDGIKANVILCSQQYLAAPLVMLKLQPDGKLLPMVIQLQLPSAGSPPPPLFLPTDPPMVWLLAKCWVRSSDFQLHELQSHLLRGHLMAEVIAVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGVFDQVVSTGGGGHVELLRRAGGFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIFRYVEGIVSLHYKTDVAVKDDPELQTWCREITEIGLQGGQDRGFPVSLQSRDQVCHFVTMCIFTCTGQHSSVHLGQLDWYTWVPNAPCTMRLPPPTTKDATLETVMATLPNFHQASLQMSITWQLGRRQPIMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIENRNAKLDMPYEYLRPSLVENSVAI

Gene Information

Entrez Gene ID
709212
Gene Name
arachidonate 15-lipoxygenase
Gene Symbol
ALOX15
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IEA:Ensembl C cytosol
GO:0031234 IEA:Ensembl C extrinsic component of cytoplasmic side of plasma membrane
GO:0005811 IEA:Ensembl C lipid particle
GO:0004052 IEA:Ensembl F arachidonate 12-lipoxygenase activity
GO:0050473 IEA:Ensembl F arachidonate 15-lipoxygenase activity
GO:0005506 IEA:InterPro F iron ion binding
GO:0005546 IEA:Ensembl F phosphatidylinositol-4,5-bisphosphate binding
GO:0043277 IEA:Ensembl P apoptotic cell clearance
GO:0019369 IEA:Ensembl P arachidonic acid metabolic process
GO:0030282 IEA:Ensembl P bone mineralization
GO:0071277 IEA:Ensembl P cellular response to calcium ion
GO:0035963 IEA:Ensembl P cellular response to interleukin-13
GO:2001303 IEA:Ensembl P lipoxin A4 biosynthetic process
GO:0019372 IEA:Ensembl P lipoxygenase pathway
GO:0002820 IEA:Ensembl P negative regulation of adaptive immune response
GO:0006646 IEA:Ensembl P phosphatidylethanolamine biosynthetic process
GO:0070374 IEA:Ensembl P positive regulation of ERK1 and ERK2 cascade
GO:0030838 IEA:Ensembl P positive regulation of actin filament polymerization
GO:0010811 IEA:Ensembl P positive regulation of cell-substrate adhesion
GO:1901074 IEA:Ensembl P regulation of engulfment of apoptotic cell
GO:0035358 IEA:Ensembl P regulation of peroxisome proliferator activated receptor signaling pathway
GO:0034976 IEA:Ensembl P response to endoplasmic reticulum stress
GO:0042060 IEA:Ensembl P wound healing

KEGG Pathway Links

KEGG Pathway ID Description
ko00590 Arachidonic acid metabolism
mcc00590 Arachidonic acid metabolism
ko00591 Linoleic acid metabolism
mcc00591 Linoleic acid metabolism
mcc01100 Metabolic pathways
mcc04726 Serotonergic synapse

Domain Information

InterPro Annotations

Accession Description
IPR008976 Lipase/lipooxygenase, PLAT/LH2
IPR000907 Lipoxygenase
IPR013819 Lipoxygenase, C-terminal
IPR020834 Lipoxygenase, conserved site
IPR020833 Lipoxygenase, iron binding site
IPR001885 Lipoxygenase, mammalian
IPR001024 PLAT/LH2 domain

UniProt Annotations

Entry Information

Gene Name
arachidonate 15-lipoxygenase
Protein Entry
F7EPQ4_MACMU
UniProt ID
F7EPQ4
Species
Rhesus monkey

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Cofactor Note=Iron. ;
Similarity Belongs to the lipoxygenase family.
Similarity Contains PLAT domain.
Similarity Contains lipoxygenase domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP013779 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109112842 RefSeq XP_001094627 662 arachidonate 15-lipoxygenase
297271648 RefSeq XP_002800298 623 arachidonate 15-lipoxygenase

Identical Sequences to LMP013779 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP013779 proteins

Reference Database Accession Length Protein Name
GI:297271648 GenBank EHH24392.1 662 Arachidonate 15-lipoxygenase [Macaca mulatta]
GI:297271648 GenBank EHH57602.1 662 Arachidonate 15-lipoxygenase [Macaca fascicularis]
GI:297271648 RefSeq XP_005582628.1 662 PREDICTED: arachidonate 15-lipoxygenase [Macaca fascicularis]
GI:297271648 RefSeq XP_009187662.1 662 PREDICTED: arachidonate 15-lipoxygenase [Papio anubis]