Gene/Proteome Database (LMPD)
Proteins
| adiponectin precursor | |
|---|---|
| Refseq ID | NP_001028043 |
| Protein GI | 74136307 |
| UniProt ID | Q95JD7 |
| mRNA ID | NM_001032871 |
| Length | 243 |
| MLLGAVLLLLALPSHGQDTTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGVPGRDGRDGTPGEKGEKGDPGLIGPKGDTGETGVTGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLETYVTVPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLYHDTN | |
| sig_peptide: 1..16 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1618 peptide sequence: MLLGAVLLLLALPSHG | |
Gene Information
Entrez Gene ID
Gene Name
adiponectin, C1Q and collagen domain containing
Gene Symbol
Species
Macaca mulatta
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0071944 | ISS:UniProtKB | C | cell periphery |
| GO:0009986 | ISS:BHF-UCL | C | cell surface |
| GO:0005581 | IEA:UniProtKB-KW | C | collagen trimer |
| GO:0005783 | ISS:UniProtKB | C | endoplasmic reticulum |
| GO:0005615 | ISS:UniProtKB | C | extracellular space |
| GO:0048471 | ISS:UniProtKB | C | perinuclear region of cytoplasm |
| GO:0005179 | ISS:UniProtKB | F | hormone activity |
| GO:0005102 | ISS:UniProtKB | F | receptor binding |
| GO:0033211 | IEA:InterPro | P | adiponectin-activated signaling pathway |
| GO:0050873 | ISS:UniProtKB | P | brown fat cell differentiation |
| GO:0035690 | ISS:UniProtKB | P | cellular response to drug |
| GO:0032869 | ISS:UniProtKB | P | cellular response to insulin stimulus |
| GO:0070994 | ISS:UniProtKB | P | detection of oxidative stress |
| GO:0006635 | ISS:UniProtKB | P | fatty acid beta-oxidation |
| GO:0019395 | ISS:UniProtKB | P | fatty acid oxidation |
| GO:0042593 | ISS:UniProtKB | P | glucose homeostasis |
| GO:0006006 | ISS:UniProtKB | P | glucose metabolic process |
| GO:0034383 | ISS:UniProtKB | P | low-density lipoprotein particle clearance |
| GO:2000279 | ISS:UniProtKB | P | negative regulation of DNA biosynthetic process |
| GO:0070373 | ISS:UniProtKB | P | negative regulation of ERK1 and ERK2 cascade |
| GO:0043124 | ISS:UniProtKB | P | negative regulation of I-kappaB kinase/NF-kappaB signaling |
| GO:0043407 | ISS:UniProtKB | P | negative regulation of MAP kinase activity |
| GO:0045776 | ISS:UniProtKB | P | negative regulation of blood pressure |
| GO:0030336 | ISS:UniProtKB | P | negative regulation of cell migration |
| GO:0045599 | ISS:UniProtKB | P | negative regulation of fat cell differentiation |
| GO:0045721 | ISS:UniProtKB | P | negative regulation of gluconeogenesis |
| GO:0030853 | ISS:UniProtKB | P | negative regulation of granulocyte differentiation |
| GO:0034115 | ISS:UniProtKB | P | negative regulation of heterotypic cell-cell adhesion |
| GO:0050728 | ISS:UniProtKB | P | negative regulation of inflammatory response |
| GO:0090317 | ISS:UniProtKB | P | negative regulation of intracellular protein transport |
| GO:0045715 | ISS:UniProtKB | P | negative regulation of low-density lipoprotein particle receptor biosynthetic process |
| GO:0010745 | ISS:UniProtKB | P | negative regulation of macrophage derived foam cell differentiation |
| GO:0045650 | ISS:UniProtKB | P | negative regulation of macrophage differentiation |
| GO:2000590 | ISS:UniProtKB | P | negative regulation of metanephric mesenchymal cell migration |
| GO:0050765 | ISS:UniProtKB | P | negative regulation of phagocytosis |
| GO:0010642 | ISS:UniProtKB | P | negative regulation of platelet-derived growth factor receptor signaling pathway |
| GO:2000584 | ISS:UniProtKB | P | negative regulation of platelet-derived growth factor receptor-alpha signaling pathway |
| GO:0031953 | ISS:UniProtKB | P | negative regulation of protein autophosphorylation |
| GO:1900121 | ISS:UniProtKB | P | negative regulation of receptor binding |
| GO:0014912 | ISS:UniProtKB | P | negative regulation of smooth muscle cell migration |
| GO:0048662 | ISS:UniProtKB | P | negative regulation of smooth muscle cell proliferation |
| GO:0050805 | ISS:UniProtKB | P | negative regulation of synaptic transmission |
| GO:0045892 | ISS:UniProtKB | P | negative regulation of transcription, DNA-templated |
| GO:0032720 | ISS:UniProtKB | P | negative regulation of tumor necrosis factor production |
| GO:0010804 | ISS:UniProtKB | P | negative regulation of tumor necrosis factor-mediated signaling pathway |
| GO:0043123 | ISS:UniProtKB | P | positive regulation of I-kappaB kinase/NF-kappaB signaling |
| GO:2000481 | ISS:UniProtKB | P | positive regulation of cAMP-dependent protein kinase activity |
| GO:0032270 | ISS:BHF-UCL | P | positive regulation of cellular protein metabolic process |
| GO:0010875 | ISS:BHF-UCL | P | positive regulation of cholesterol efflux |
| GO:0045923 | ISS:UniProtKB | P | positive regulation of fatty acid metabolic process |
| GO:0046326 | ISS:UniProtKB | P | positive regulation of glucose import |
| GO:2000467 | ISS:UniProtKB | P | positive regulation of glycogen (starch) synthase activity |
| GO:0032757 | ISS:UniProtKB | P | positive regulation of interleukin-8 production |
| GO:2000478 | ISS:UniProtKB | P | positive regulation of metanephric glomerular visceral epithelial cell development |
| GO:0071639 | ISS:UniProtKB | P | positive regulation of monocyte chemotactic protein-1 production |
| GO:0033034 | ISS:UniProtKB | P | positive regulation of myeloid cell apoptotic process |
| GO:0010739 | ISS:UniProtKB | P | positive regulation of protein kinase A signaling |
| GO:0001934 | ISS:UniProtKB | P | positive regulation of protein phosphorylation |
| GO:2000534 | ISS:UniProtKB | P | positive regulation of renal albumin absorption |
| GO:0009967 | ISS:UniProtKB | P | positive regulation of signal transduction |
| GO:0051260 | ISS:UniProtKB | P | protein homooligomerization |
| GO:0072659 | ISS:UniProtKB | P | protein localization to plasma membrane |
| GO:0010906 | ISS:UniProtKB | P | regulation of glucose metabolic process |
| GO:0009749 | ISS:UniProtKB | P | response to glucose |
| GO:0034612 | ISS:UniProtKB | P | response to tumor necrosis factor |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ko04152 | AMPK signaling pathway |
| mcc04152 | AMPK signaling pathway |
| ko04920 | Adipocytokine signaling pathway |
| mcc04920 | Adipocytokine signaling pathway |
| ko04932 | Non-alcoholic fatty liver disease (NAFLD) |
| mcc04932 | Non-alcoholic fatty liver disease (NAFLD) |
| ko03320 | PPAR signaling pathway |
| mcc03320 | PPAR signaling pathway |
| ko04930 | Type II diabetes mellitus |
| mcc04930 | Type II diabetes mellitus |
Domain Information
UniProt Annotations
Entry Information
Gene Name
adiponectin, C1Q and collagen domain containing
Protein Entry
Q95JD7_MACMU
UniProt ID
Species
Rhesus monkey
Identical and Related Proteins
Unique RefSeq proteins for LMP013736 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 74136307 | RefSeq | NP_001028043 | 243 | adiponectin precursor |
Identical Sequences to LMP013736 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:74136307 | GenBank | AER78341.1 | 243 | Sequence 16 from patent US 8044182 |
| GI:74136307 | GenBank | EHH16836.1 | 243 | hypothetical protein EGK_12195 [Macaca mulatta] |
| GI:74136307 | GenBank | EHH51751.1 | 243 | hypothetical protein EGM_11189 [Macaca fascicularis] |
| GI:74136307 | RefSeq | XP_005545517.1 | 243 | PREDICTED: adiponectin isoform X2 [Macaca fascicularis] |
Related Sequences to LMP013736 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:74136307 | GenBank | ACE15889.1 | 243 | Sequence 16 from patent US 7365170 |
| GI:74136307 | GenBank | ADF22675.1 | 243 | Sequence 4 from patent US 7678886 |