Gene/Proteome Database (LMPD)

LMPD ID
LMP013572
Gene ID
498475
Species
Rattus norvegicus (Rat)
Gene Name
prostaglandin D2 receptor-like
Gene Symbol
Ptgdr
Synonyms
RGD1565108;
Alternate Names
prostaglandin D2 receptor; PGD receptor; PGD2 receptor; prostanoid DP receptor; prostaglandin D receptor;
Chromosome
15
Map Location
15p14

Proteins

prostaglandin D2 receptor
Refseq ID NP_001128636
Protein GI 206597432
UniProt ID Q9R261
mRNA ID NM_001135164
Length 357
MNESYRCQAATWVERGSSATMGGVAFSAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNRSLKELLPASGNQLCEAFAFLMSFFGLASTLQLLAMALECWLSLGHPFFYQRHITARRGVLVAPVAGAFSLAFCALPFAGFGKFVQYCPGTWCFIQMIHKKRSFSVIGFSVLYSSLMALLVLATVVCNLGAMSNLYAMHRRQRHHPRRCSRDRAQSGSDYRHGSPNPLEELDHFVLLALTTVLFTMCSLPLIYRAYYGAFKLVDRADGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKTFTRPLIYRNWCSHSWQTNMESTL

Gene Information

Entrez Gene ID
498475
Gene Name
prostaglandin D2 receptor-like
Gene Symbol
Ptgdr
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IEA:UniProtKB-KW C plasma membrane
GO:0004956 IEA:InterPro F prostaglandin D receptor activity

KEGG Pathway Links

KEGG Pathway ID Description
ko04080 Neuroactive ligand-receptor interaction
rno04080 Neuroactive ligand-receptor interaction

Domain Information

InterPro Annotations

Accession Description
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
IPR000376 Prostaglandin D receptor
IPR008365 Prostanoid receptor

UniProt Annotations

Entry Information

Gene Name
prostaglandin D2 receptor-like
Protein Entry
PD2R_RAT
UniProt ID
Q9R261
Species
Rat

Comments

Comment Type Description
Function Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate
Similarity Belongs to the G-protein coupled receptor 1 family
Subcellular Location Cell membrane ; Multi-pass membrane protein .
Tissue Specificity Strongly expressed in eye and gastrointestinal tract (GIT), moderately in the brain and oviduct and weakly in the epididymis. In the eye, expressed in the epithelium of the iris and ciliary body and in photoreceptor cells of the retina. In the brain, expressed in leptomeninges, choroid plexus and spinal cord (sensory and motor neurons of the dorsal and ventral horns). In the stomach, expressed in the mucous-secreting goblet cells and the columnar epithelium. Expressed in platelets

Identical and Related Proteins

Unique RefSeq proteins for LMP013572 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
206597432 RefSeq NP_001128636 357 prostaglandin D2 receptor

Identical Sequences to LMP013572 proteins

Reference Database Accession Length Protein Name
GI:206597432 GenBank ABP08274.1 357 Sequence 16 from patent US 7183062
GI:206597432 GenBank ACN08920.1 357 Sequence 16 from patent US 7488799
GI:206597432 GenBank ADL99486.1 357 Sequence 16 from patent US 7723074
GI:206597432 SwissProt Q9R261.1 357 RecName: Full=Prostaglandin D2 receptor; Short=PGD receptor; Short=PGD2 receptor; AltName: Full=Prostanoid DP receptor [Rattus norvegicus]

Related Sequences to LMP013572 proteins

Reference Database Accession Length Protein Name
GI:206597432 GenBank AAD23564.1 357 prostaglandin D2 receptor [Rattus norvegicus]
GI:206597432 GenBank ABP08274.1 357 Sequence 16 from patent US 7183062
GI:206597432 GenBank ADL99486.1 357 Sequence 16 from patent US 7723074
GI:206597432 SwissProt Q9R261.1 357 RecName: Full=Prostaglandin D2 receptor; Short=PGD receptor; Short=PGD2 receptor; AltName: Full=Prostanoid DP receptor [Rattus norvegicus]