Gene/Proteome Database (LMPD)

LMPD ID
LMP013411
Gene ID
353233
Species
Rattus norvegicus (Rat)
Gene Name
neutral sphingomyelinase (N-SMase) activation associated factor
Gene Symbol
Nsmaf
Synonyms
FAN;
Alternate Names
protein FAN; factor associated with neutral sphingomyelinase activation;
Chromosome
5
Map Location
5q12
Summary
cytopasmic protein; mediates activation of sphingomyelinase and apoptosis [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Nsmaf

Proteins

protein FAN
Refseq ID NP_852054
Protein GI 31077098
UniProt ID Q7TSY5
mRNA ID NM_181389
Length 920
MAFTRKRQREQQLQLYSKERFSLLLLNLEEYYFEQHTAFHVQHQGSPEERKIRGSLKICSKSVIFEPDAISQPILKIPLRDCLKIGKHGENGANKHFAKAKSLGISLISSQVYFIKEHNIVAPYKIERGKMEYVFQLEVSGKVEDVVETLLQLHRASCLDKLGDQMAMITAILQSRLARTSFDKNRFQSVSEKLHMECKAEMMTPLVTNSGHVCITDTNLYFQPLNGYPKPVVQITLQDVRRIYKRRHGLMPLGLEVFCTEDDLCSDIYLKFYEPQDRDDLYFYIATYLEHHVAEHTAESYMLQWQRGHLSNYQYLLHFNNLADRGCNDLSQYPVFPWVISDYSNPELDLSNPATFRDLSKPVGALNPERLERLLTRYQEMPEPKFMYGSHYSSPGYVLFYLVRIAPEYMLCLQNGRFDNADRMFNSIVETWKNCLDGATNFKELIPEFYDEDASFLINSLKLDLGKRQGGQMVDDVELPAWASSPQDFLQKNKDALESSYVSEHLHEWIDLIFGYKQKGSEAIGAHNVFHPLTYEGGVDLNSIEDPDDKVAMLTQILEFGQTPKQLFVTPHPRRITPKFKSLSQASSYNASMTDSPVSPGEESFEDLTEESKTLAWNNITKLQLHEQYKIHKEAVTGIAVSCNGSSVFTTSQDSTLKMFSKESKMLQRSISFSIWALSSCLLLPGDTTVISSSWDNNVYFYSIAFGRRQDTLMGHDDAVSKICWHNDRLYSASWDSTVKVWSGVPAEMPGTKRHQFDLLAELEHDVSVNTINLNAVSTLLVSGTKEGLVNIWDLTTATLLHQISCHSGTVCDAAFSPDSRHVLSTGVDGCLNVIDVQTGMLISSMASEEPQRCFVWDGNSVVSGSRTGELLVWDLLGAKVSERIQGHTGAVTCIRMNEQCSSIITGGEDRQVMFWKLQY

Gene Information

Entrez Gene ID
353233
Gene Name
neutral sphingomyelinase (N-SMase) activation associated factor
Gene Symbol
Nsmaf
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016230 IMP:RGD F sphingomyelin phosphodiesterase activator activity
GO:0043065 IDA:RGD P positive regulation of apoptotic process
GO:0043085 IMP:GOC P positive regulation of catalytic activity

Domain Information

InterPro Annotations

Accession Description
IPR000409 BEACH domain
IPR004182 GRAM domain
IPR023362 PH-BEACH domain
IPR017986 WD40-repeat-containing domain
IPR015943 WD40/YVTN repeat-like-containing domain
IPR001680 WD40_repeat

UniProt Annotations

Entry Information

Gene Name
neutral sphingomyelinase (N-SMase) activation associated factor
Protein Entry
Q7TSY5_RAT
UniProt ID
Q7TSY5
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013411 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
31077098 RefSeq NP_852054 920 protein FAN

Identical Sequences to LMP013411 proteins

Reference Database Accession Length Protein Name
GI:31077098 GenBank AAO00726.1 920 neutral sphingomyelinase activation associated factor [Rattus norvegicus]

Related Sequences to LMP013411 proteins

Reference Database Accession Length Protein Name
GI:31077098 GenBank AAO00726.1 920 neutral sphingomyelinase activation associated factor [Rattus norvegicus]
GI:31077098 GenBank EDL05686.1 920 neutral sphingomyelinase (N-SMase) activation associated factor, isoform CRA_b [Mus musculus]
GI:31077098 GenBank AAI45962.1 920 Neutral sphingomyelinase (N-SMase) activation associated factor [Mus musculus]
GI:31077098 RefSeq XP_008761766.1 920 PREDICTED: protein FAN isoform X1 [Rattus norvegicus]