Gene/Proteome Database (LMPD)

LMPD ID
LMP013358
Gene ID
313339
Species
Rattus norvegicus (Rat)
Gene Name
alkaline ceramidase 2
Gene Symbol
Acer2
Synonyms
Asah3l;
Alternate Names
alkaline ceramidase 2;
Chromosome
5
Map Location
5q32

Proteins

alkaline ceramidase 2
Refseq ID NP_001101413
Protein GI 157817955
UniProt ID D3ZNW4
mRNA ID NM_001107943
Length 275
MGAPHWWDQLRAGSSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVVVGIGSVYFHATLSFLGQMLDELAILWVLMCALAMWFPRRYLPKIFRNDRGRFKAVVCVLSAVTTCLAFVKPAINNISLMILGVPCTALLIAELKRCDNVRVFKLGLFSGLWWTLALFCWISDRAFCELLSSFHFPYLHCVWHILICLAAYLGCVCFAYFDAASEIPEQGPVIRFWPSEKWAFIGVPYVSLLCAHKKSPVKIT

Gene Information

Entrez Gene ID
313339
Gene Name
alkaline ceramidase 2
Gene Symbol
Acer2
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0030173 IEA:Ensembl C integral component of Golgi membrane
GO:0071633 IEA:Ensembl F dihydroceramidase activity
GO:0006919 IEA:Ensembl P activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0035690 IEA:Ensembl P cellular response to drug
GO:0006672 IEA:InterPro P ceramide metabolic process
GO:0033629 IEA:Ensembl P negative regulation of cell adhesion mediated by integrin
GO:0001953 IEA:Ensembl P negative regulation of cell-matrix adhesion
GO:0090285 IEA:Ensembl P negative regulation of protein glycosylation in Golgi
GO:0010942 IEA:Ensembl P positive regulation of cell death
GO:0008284 IEA:Ensembl P positive regulation of cell proliferation
GO:0032526 IEA:Ensembl P response to retinoic acid
GO:0046512 IEA:Ensembl P sphingosine biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
rno01100 Metabolic pathways
ko00600 Sphingolipid metabolism
rno00600 Sphingolipid metabolism
M00099 Sphingosine biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5954266 Sphingolipid de novo biosynthesis
5954267 Sphingolipid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR008901 Ceramidase

UniProt Annotations

Entry Information

Gene Name
alkaline ceramidase 2
Protein Entry
D3ZNW4_RAT
UniProt ID
D3ZNW4
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013358 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
157817955 RefSeq NP_001101413 275 alkaline ceramidase 2

Identical Sequences to LMP013358 proteins

Reference Database Accession Length Protein Name
GI:157817955 GenBank EDL76006.1 275 N-acylsphingosine amidohydrolase 3-like (predicted), isoform CRA_a [Rattus norvegicus]
GI:157817955 RefSeq XP_006238425.1 275 PREDICTED: alkaline ceramidase 2 isoform X1 [Rattus norvegicus]

Related Sequences to LMP013358 proteins

Reference Database Accession Length Protein Name
GI:157817955 GenBank EDL76006.1 275 N-acylsphingosine amidohydrolase 3-like (predicted), isoform CRA_a [Rattus norvegicus]
GI:157817955 RefSeq XP_003472260.1 275 PREDICTED: alkaline ceramidase 2 [Cavia porcellus]
GI:157817955 RefSeq XP_006238425.1 275 PREDICTED: alkaline ceramidase 2 isoform X1 [Rattus norvegicus]
GI:157817955 SwissProt Q8VD53.1 275 RecName: Full=Alkaline ceramidase 2; Short=AlkCDase 2; Short=Alkaline CDase 2; Short=maCER2; AltName: Full=Acylsphingosine deacylase 3-like; AltName: Full=Cancer-related gene liver 1 protein; Short=CRG-L1; AltName: Full=N-acylsphingosine amidohydrolase 3-like [Mus musculus]