Gene/Proteome Database (LMPD)

LMPD ID
LMP013202
Gene ID
301120
Species
Rattus norvegicus (Rat)
Gene Name
acyl-CoA synthetase bubblegum family member 2
Gene Symbol
Acsbg2
Alternate Names
long-chain-fatty-acid--CoA ligase ACSBG2; bubblegum-related acyl-CoA synthetase 2;
Chromosome
9
Map Location
9q11
EC Number
6.2.1.3

Proteins

long-chain-fatty-acid--CoA ligase ACSBG2
Refseq ID NP_001073565
Protein GI 121583863
UniProt ID A1L1K7
mRNA ID NM_001080096
Length 667
MTQEKKAEDPDRGMDTTSAAPRLWSTHCDGEVLLRLSKHGPGHETPMTIPELFQESVERFGAYPALASKNGKKWDTLTFSQYYDVCRKAARSLIKLGLQRFHGVGILGFNSVEWVVAALGAILAGGLCVGIYATNSAEACQYVIKQANVNVLIVENDQQLQKILSIPPDKMETVKAIVQYRLPLMENSTNLYSWQDFMELGNAIPNIQLDRVILSQKANQCAVIIYTSGTTGSPKGVMLSHDNITWTAGAMAREIELIHVSGKQDTIVSYLPLSHIAAQLMDIWIPIKVGVLTFFAQPDALRGTLVYTLQEVKPTYFLGVPRVWEKMQDTIKENVAKSSNLRKKAFAWAKMLGLKVNTKKMLGKRDIPMNYRMAKALVFTKVRTSLGLDNCHTFFSGASPLSQDVSEFFLSLDIPIGEIYGMTECSGPHTVSCKSIYRVLSCGKVLNGCKNMLYKQNKDGVGEVCMWGRHVFMGYLGKEDATLEVLDEDGWLHSGDIGRLDSHDFLYITGRIKEVLITAGGENIWPIPIETLVKEKIPIISHAMLVGDKAKFLSMLLTLKCETDQMSGEPLDKLNLEAISFCQMLGSQAVTVSDILKIRDPVVYTAIQYGIDIVNQQAVSDSHRIRKWIILEKDFSIQGGELGPTSKLKRDLITQKYKAQIDNMYSS

Gene Information

Entrez Gene ID
301120
Gene Name
acyl-CoA synthetase bubblegum family member 2
Gene Symbol
Acsbg2
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IEA:Ensembl C cytosol
GO:0016020 IEA:UniProtKB-KW C membrane
GO:0005739 IEA:Ensembl C mitochondrion
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0047617 IEA:Ensembl F acyl-CoA hydrolase activity
GO:0004467 IEA:UniProtKB-EC F long-chain fatty acid-CoA ligase activity
GO:0030154 IEA:UniProtKB-KW P cell differentiation
GO:0007275 IEA:UniProtKB-KW P multicellular organismal development
GO:0007283 IEA:UniProtKB-KW P spermatogenesis

KEGG Pathway Links

KEGG Pathway ID Description
ko04920 Adipocytokine signaling pathway
rno04920 Adipocytokine signaling pathway
ko00061 Fatty acid biosynthesis
rno00061 Fatty acid biosynthesis
ko00071 Fatty acid degradation
rno00071 Fatty acid degradation
ko01212 Fatty acid metabolism
rno01212 Fatty acid metabolism
rno01100 Metabolic pathways
ko03320 PPAR signaling pathway
rno03320 PPAR signaling pathway
M00086 beta-Oxidation, acyl-CoA synthesis

Domain Information

InterPro Annotations

Accession Description
IPR020845 AMP-binding, conserved site
IPR000873 AMP-dependent synthetase/ligase

UniProt Annotations

Entry Information

Gene Name
acyl-CoA synthetase bubblegum family member 2
Protein Entry
ACBG2_RAT
UniProt ID
A1L1K7
Species
Rat

Comments

Comment Type Description
Catalytic Activity ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA.
Function Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis (By similarity)
Similarity Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily
Subcellular Location Cytoplasm . Membrane {ECO:0000250}; Peripheral membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP013202 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
121583863 RefSeq NP_001073565 667 long-chain-fatty-acid--CoA ligase ACSBG2

Identical Sequences to LMP013202 proteins

Reference Database Accession Length Protein Name
GI:121583863 GenBank AAI29111.1 667 Acyl-CoA synthetase bubblegum family member 2 [Rattus norvegicus]
GI:121583863 SwissProt A1L1K7.1 667 RecName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2; AltName: Full=Acyl-CoA synthetase bubblegum family member 2 [Rattus norvegicus]

Related Sequences to LMP013202 proteins

Reference Database Accession Length Protein Name
GI:121583863 GenBank AAI29111.1 667 Acyl-CoA synthetase bubblegum family member 2 [Rattus norvegicus]
GI:121583863 GenBank EDL83602.1 698 similar to lipidosin [Rattus norvegicus]
GI:121583863 RefSeq XP_006244373.1 698 PREDICTED: long-chain-fatty-acid--CoA ligase ACSBG2 isoform X1 [Rattus norvegicus]
GI:121583863 SwissProt A1L1K7.1 667 RecName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2; AltName: Full=Acyl-CoA synthetase bubblegum family member 2 [Rattus norvegicus]