Gene/Proteome Database (LMPD)

LMPD ID
LMP013148
Gene ID
296849
Species
Rattus norvegicus (Rat)
Gene Name
pyruvate dehydrogenase kinase, isozyme 3
Gene Symbol
Pdk3
Alternate Names
pyruvate dehydrogenase kinase, isozyme 3; Pyruvate dehydrogenase kinase 3; pyruvate dehydrogenase kinase, isoenzyme 3; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial;
Chromosome
X
Map Location
Xq22

Proteins

pyruvate dehydrogenase kinase, isozyme 3
Refseq ID NP_001100051
Protein GI 157819147
UniProt ID B5DFI9
mRNA ID NM_001106581
Length 415
MRLFYRLLKQPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPRVLDNFLHVLINIRNRHNDVVPTMAQGVIEYKEKFGFDPFISSNIQYFLDRFYTNRISFRMLINQHTLLFGGDTNPAHPKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPNKPIQVVYVPSHLFHMLFELFKNSMRATVELYEDKKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSTAPRPSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKAKQDKIKSNKTF

Gene Information

Entrez Gene ID
296849
Gene Name
pyruvate dehydrogenase kinase, isozyme 3
Gene Symbol
Pdk3
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IEA:Ensembl C mitochondrion
GO:0005524 IEA:Ensembl F ATP binding
GO:0004674 IEA:Ensembl F protein serine/threonine kinase activity
GO:0004740 IEA:Ensembl F pyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0071398 IEA:Ensembl P cellular response to fatty acid
GO:0071333 IMP:UniProtKB P cellular response to glucose stimulus
GO:0097411 IEA:Ensembl P hypoxia-inducible factor-1alpha signaling pathway
GO:0018105 IEA:Ensembl P peptidyl-serine phosphorylation
GO:0035357 IEA:Ensembl P peroxisome proliferator activated receptor signaling pathway
GO:0010510 IEA:Ensembl P regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010906 IEA:Ensembl P regulation of glucose metabolic process
GO:2000377 IEA:Ensembl P regulation of reactive oxygen species metabolic process

REACTOME Pathway Links

REACTOME Pathway ID Description
5953250 Metabolism
5953268 Pyruvate metabolism
5953269 Pyruvate metabolism and Citric Acid (TCA) cycle
5954047 Regulation of pyruvate dehydrogenase (PDH) complex
5953270 The citric acid (TCA) cycle and respiratory electron transport

Domain Information

InterPro Annotations

Accession Description
IPR018955 Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal
IPR003594 Histidine kinase-like ATPase, C-terminal domain
IPR005467 Signal transduction histidine kinase, core

UniProt Annotations

Entry Information

Gene Name
pyruvate dehydrogenase kinase, isozyme 3
Protein Entry
B5DFI9_RAT
UniProt ID
B5DFI9
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013148 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
157819147 RefSeq NP_001100051 415 pyruvate dehydrogenase kinase, isozyme 3

Identical Sequences to LMP013148 proteins

Reference Database Accession Length Protein Name
GI:157819147 GenBank AAI69078.1 415 Pdk3 protein [Rattus norvegicus]
GI:157819147 RefSeq XP_006257080.1 415 PREDICTED: pyruvate dehydrogenase kinase, isozyme 3 isoform X2 [Rattus norvegicus]
GI:157819147 RefSeq XP_006257081.1 415 PREDICTED: pyruvate dehydrogenase kinase, isozyme 3 isoform X2 [Rattus norvegicus]
GI:157819147 RefSeq XP_006257082.1 415 PREDICTED: pyruvate dehydrogenase kinase, isozyme 3 isoform X1 [Rattus norvegicus]

Related Sequences to LMP013148 proteins

Reference Database Accession Length Protein Name
GI:157819147 GenBank EDL96013.1 415 pyruvate dehydrogenase kinase, isoenzyme 3 (mapped), isoform CRA_a [Rattus norvegicus]
GI:157819147 RefSeq XP_006257080.1 415 PREDICTED: pyruvate dehydrogenase kinase, isozyme 3 isoform X2 [Rattus norvegicus]
GI:157819147 RefSeq XP_006257081.1 415 PREDICTED: pyruvate dehydrogenase kinase, isozyme 3 isoform X2 [Rattus norvegicus]
GI:157819147 RefSeq XP_006257082.1 415 PREDICTED: pyruvate dehydrogenase kinase, isozyme 3 isoform X1 [Rattus norvegicus]