Gene/Proteome Database (LMPD)

LMPD ID
LMP013121
Gene ID
294421
Species
Rattus norvegicus (Rat)
Gene Name
serine incorporator 1
Gene Symbol
Serinc1
Synonyms
Tde2; Tde1l; LRRGT00191;
Alternate Names
serine incorporator 1; tumor differentially expressed 1, like; tumor differentially expressed protein 2;
Chromosome
20
Map Location
20q11
Summary
human homolog is a central nervous system specific transmembrane protein [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Serinc1

Proteins

serine incorporator 1 precursor
Refseq ID NP_891996
Protein GI 33636726
UniProt ID Q7TNK0
mRNA ID NM_182951
Length 453
MGSVLGLCSVASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFATAVAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIILFFVYYTHPASCSENKAFISVNMLLCIGASVMSILPKIQESQPRSGLLQSSVITIYTMYLTWSAMTNEPETNCNPSLLSIIGFNTTRPVPKDGQSVQWWHPQGIIGLVLFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGNGRSDGSLDDGEGVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD
sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1896 peptide sequence: MGSVLGLCSVASWIPCLCG

Gene Information

Entrez Gene ID
294421
Gene Name
serine incorporator 1
Gene Symbol
Serinc1
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 IDA:HGNC C endoplasmic reticulum membrane
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IDA:HGNC C plasma membrane
GO:0015194 IDA:HGNC F L-serine transmembrane transporter activity
GO:0015825 IDA:HGNC P L-serine transport
GO:0006658 IDA:HGNC P phosphatidylserine metabolic process
GO:0008654 IEA:UniProtKB-KW P phospholipid biosynthetic process
GO:0051347 IDA:HGNC P positive regulation of transferase activity
GO:0006665 IDA:HGNC P sphingolipid metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR029552 Serine incorporator 1
IPR005016 Serine incorporator/TMS membrane protein

UniProt Annotations

Entry Information

Gene Name
serine incorporator 1
Protein Entry
SERC1_RAT
UniProt ID
Q7TNK0
Species
Rat

Comments

Comment Type Description
Function Enhances the incorporation of serine into phosphatidylserine and sphingolipids
Induction Up-regulated by kainate treatment in neuronal cell layers of the hippocampus
Similarity Belongs to the TDE1 family
Subcellular Location Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Subunit Interacts with SPTLC1
Tissue Specificity Detected in brain cortex, hippocampus and cerebellar granule cell layer

Identical and Related Proteins

Unique RefSeq proteins for LMP013121 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
33636726 RefSeq NP_891996 453 serine incorporator 1 precursor

Identical Sequences to LMP013121 proteins

Reference Database Accession Length Protein Name
GI:33636726 GenBank AAH88852.1 453 Serinc1 protein [Rattus norvegicus]
GI:33636726 GenBank AAZ80295.1 453 serine incorporator 1 [Rattus norvegicus]
GI:33636726 GenBank EDL92897.1 453 serine incorporator 1, isoform CRA_b [Rattus norvegicus]
GI:33636726 SwissProt Q7TNK0.1 453 RecName: Full=Serine incorporator 1; AltName: Full=Tumor differentially expressed protein 1-like; AltName: Full=Tumor differentially expressed protein 2 [Rattus norvegicus]

Related Sequences to LMP013121 proteins

Reference Database Accession Length Protein Name
GI:33636726 GenBank AAQ17069.1 453 tumor differentially expressed 1-like protein [Rattus norvegicus]
GI:33636726 GenBank AAZ80295.1 453 serine incorporator 1 [Rattus norvegicus]
GI:33636726 GenBank EDL92897.1 453 serine incorporator 1, isoform CRA_b [Rattus norvegicus]
GI:33636726 SwissProt Q7TNK0.1 453 RecName: Full=Serine incorporator 1; AltName: Full=Tumor differentially expressed protein 1-like; AltName: Full=Tumor differentially expressed protein 2 [Rattus norvegicus]