Gene/Proteome Database (LMPD)

LMPD ID
LMP013014
Gene ID
287533
Species
Rattus norvegicus (Rat)
Gene Name
inositol polyphosphate-5-phosphatase K
Gene Symbol
Inpp5k
Synonyms
Skip;
Alternate Names
inositol polyphosphate 5-phosphatase K; C62; putative phosphoinositide 5-phosphatase type II; putative phosphoinositide 5-phosphatase type II; C62; skeletal muscle and kidney enriched inositol phosphatase;
Chromosome
10
Map Location
10q24

Proteins

inositol polyphosphate 5-phosphatase K
Refseq ID NP_001013881
Protein GI 62078453
UniProt ID Q5XIU8
mRNA ID NM_001013859
Length 446
MTTASLRKPSAPKELMLSIHVVTWNVASAAPTVDLSDLLQLNNEDLNLDIYIIGLQEMNYGIISLLSDAAFEDPWSSFFMDMLSPLNLVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSIPTGLYGYWGNKGGINICLKLYGYYVSIVNCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLILWFGDMNFRIEDFGLLFVQECITKKRYKELWEKDQLFIAKKQDQLLREFQEGPLLFPPTYKFDRHSNNYDTSEKKRKPAWTDRILWRLKRQPAKANPSGFLLTQKDYVSHMTYSISDHKPVTGTFDLELNPLMSVPLITMMPEYLWTKENDMLINYTSTPEFLSSPWDWIGLYKVGMRHINDYVSYVWVGDNQVSRGNNPNQVYINISAIPDTEEQFLLCYYSNNLHSIVGISQPFKIPSGFFLREDTLSELEPQL

Gene Information

Entrez Gene ID
287533
Gene Name
inositol polyphosphate-5-phosphatase K
Gene Symbol
Inpp5k
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 ISS:UniProtKB C cytoplasm
GO:0005829 ISS:UniProtKB C cytosol
GO:0005783 ISS:UniProtKB C endoplasmic reticulum
GO:0016020 ISS:UniProtKB C membrane
GO:0043005 ISS:UniProtKB C neuron projection
GO:0005634 ISS:UniProtKB C nucleus
GO:0048471 ISS:UniProtKB C perinuclear region of cytoplasm
GO:0005886 ISS:UniProtKB C plasma membrane
GO:0001726 ISS:UniProtKB C ruffle
GO:0032587 ISS:UniProtKB C ruffle membrane
GO:0005802 ISS:UniProtKB C trans-Golgi network
GO:0016312 ISS:UniProtKB F inositol bisphosphate phosphatase activity
GO:0034595 ISS:UniProtKB F phosphatidylinositol phosphate 5-phosphatase activity
GO:0034594 ISS:UniProtKB F phosphatidylinositol trisphosphate phosphatase activity
GO:0034485 ISS:UniProtKB F phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
GO:0005000 ISS:UniProtKB F vasopressin receptor activity
GO:0007186 ISS:UniProtKB P G-protein coupled receptor signaling pathway
GO:0071320 ISS:UniProtKB P cellular response to cAMP
GO:0071364 ISS:UniProtKB P cellular response to epidermal growth factor stimulus
GO:0032870 ISS:UniProtKB P cellular response to hormone stimulus
GO:0032869 ISS:UniProtKB P cellular response to insulin stimulus
GO:0071356 ISS:UniProtKB P cellular response to tumor necrosis factor
GO:0016311 ISS:UniProtKB P dephosphorylation
GO:0042593 ISS:UniProtKB P glucose homeostasis
GO:0043922 ISS:UniProtKB P negative regulation by host of viral transcription
GO:0043407 ISS:UniProtKB P negative regulation of MAP kinase activity
GO:0051926 ISS:UniProtKB P negative regulation of calcium ion transport
GO:0035305 ISS:UniProtKB P negative regulation of dephosphorylation
GO:0010829 ISS:UniProtKB P negative regulation of glucose transport
GO:2000466 ISS:UniProtKB P negative regulation of glycogen (starch) synthase activity
GO:0045719 ISS:UniProtKB P negative regulation of glycogen biosynthetic process
GO:0046627 ISS:UniProtKB P negative regulation of insulin receptor signaling pathway
GO:0033137 ISS:UniProtKB P negative regulation of peptidyl-serine phosphorylation
GO:0010801 ISS:UniProtKB P negative regulation of peptidyl-threonine phosphorylation
GO:0051898 ISS:UniProtKB P negative regulation of protein kinase B signaling
GO:0006469 ISS:UniProtKB P negative regulation of protein kinase activity
GO:0001933 ISS:UniProtKB P negative regulation of protein phosphorylation
GO:0090315 ISS:UniProtKB P negative regulation of protein targeting to membrane
GO:0045869 ISS:UniProtKB P negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0051497 ISS:UniProtKB P negative regulation of stress fiber assembly
GO:0045892 ISS:UniProtKB P negative regulation of transcription, DNA-templated
GO:0046856 ISS:UniProtKB P phosphatidylinositol dephosphorylation
GO:2001153 ISS:UniProtKB P positive regulation of renal water transport
GO:0045893 ISS:UniProtKB P positive regulation of transcription, DNA-templated
GO:0035810 ISS:UniProtKB P positive regulation of urine volume
GO:0072661 ISS:UniProtKB P protein targeting to plasma membrane
GO:0005979 ISS:UniProtKB P regulation of glycogen biosynthetic process
GO:0097178 ISS:UniProtKB P ruffle assembly

KEGG Pathway Links

KEGG Pathway ID Description
ko00562 Inositol phosphate metabolism
rno00562 Inositol phosphate metabolism
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol
rno01100 Metabolic pathways
ko04070 Phosphatidylinositol signaling system
rno04070 Phosphatidylinositol signaling system

Domain Information

InterPro Annotations

Accession Description
IPR005135 Endonuclease/exonuclease/phosphatase
IPR000300 Inositol polyphosphate-related phosphatase

UniProt Annotations

Entry Information

Gene Name
inositol polyphosphate-5-phosphatase K
Protein Entry
Q5XIU8_RAT
UniProt ID
Q5XIU8
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013014 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
62078453 RefSeq NP_001013881 446 inositol polyphosphate 5-phosphatase K

Identical Sequences to LMP013014 proteins

Reference Database Accession Length Protein Name
GI:62078453 GenBank AAH83572.1 446 Inositol polyphosphate-5-phosphatase K [Rattus norvegicus]
GI:62078453 GenBank EDM05234.1 446 similar to putative phosphoinositide 5-phosphatase type II; C62, isoform CRA_b [Rattus norvegicus]

Related Sequences to LMP013014 proteins

Reference Database Accession Length Protein Name
GI:62078453 GenBank AAC60757.1 468 putative phosphoinositide 5-phosphatase type II [Mus musculus]
GI:62078453 GenBank AAC53265.1 468 putative phosphoinositide 5-phosphatase type II [Mus musculus]
GI:62078453 GenBank AAH83572.1 446 Inositol polyphosphate-5-phosphatase K [Rattus norvegicus]
GI:62078453 GenBank EDM05234.1 446 similar to putative phosphoinositide 5-phosphatase type II; C62, isoform CRA_b [Rattus norvegicus]