Gene/Proteome Database (LMPD)

LMPD ID
LMP012979
Gene ID
252898
Species
Rattus norvegicus (Rat)
Gene Name
acyl-CoA oxidase 2, branched chain
Gene Symbol
Acox2
Synonyms
THCCox;
Alternate Names
peroxisomal acyl-coenzyme A oxidase 2; THCA-CoA oxidase; trihydroxycoprostanoyl-CoA oxidase; acyl-Coenzyme A oxidase 2, branched chain; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase;
Chromosome
15
Map Location
15p14
Summary
plays a role in fatty acid metabolism [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Acox2

Proteins

peroxisomal acyl-coenzyme A oxidase 2
Refseq ID NP_665713
Protein GI 404385149
UniProt ID F1LNW3
mRNA ID NM_145770
Length 681
MGSPMHRVSLGDTWSWQVHPDIDSERHSPSFSVERLTNILDGGLPNTVLRRKVESIIQSDPVFNLKKLYFMTREELYEDAIQKRFHLEKLAWSLGWSEDGPERIYANRVLDGNVNLSLHGVAMNAIRSLGSDEQIAKWGQLCKNFQIITTYAQTELGHGTYLQGLETEATYDEARQEFVIHSPTMTSTKWWPGDLGWSVTHAVVLAQLTCLGVRHGMHAFIVPIRSLEDHTPLPGITVGDIGPKMGLEHIDNGFLQLNHVRVPRENMLSRFAEVLPDGTYQRLGTPQSNYLGMLVTRVQLLCKGILPSLQKACIIATRYSVIRHQSRLRPSDPEAKILEYQTQQQKLLPQLAVSYAFHFTATSLSEFFHSSYSAILKRDFSLLPELHALSTGMKATFADFCAQGAEICRRACGGHGYSKLSGLPTLVARATASCTYEGENTVLYLQVARFLMKSYLQAQASPGATPQKPLPQSVMYIATQRPARCSAQTAADFRCPDVYTTAWAYVSTRLIRDAAHRTQTLMKSGVDQHDAWNQTTVIHLQAAKAYCYFITVKNFKEAVEKLDKEPEIQRVLQRLCDLYALHGVLTNSGDFLHDGFLSGAQVDMAREAFLDLLPLIRKDAILLTDAFDFSDHCLNSALGCYDGHVYERLFEWAQKSPANTQENPAYKKYIRPLMLGWRHKM

Gene Information

Entrez Gene ID
252898
Gene Name
acyl-CoA oxidase 2, branched chain
Gene Symbol
Acox2
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005777 IEA:InterPro C peroxisome
GO:0003995 IEA:InterPro F acyl-CoA dehydrogenase activity
GO:0003997 IEA:InterPro F acyl-CoA oxidase activity
GO:0050660 IEA:InterPro F flavin adenine dinucleotide binding
GO:0006635 IEA:InterPro P fatty acid beta-oxidation

KEGG Pathway Links

KEGG Pathway ID Description
rno01100 Metabolic pathways
ko03320 PPAR signaling pathway
rno03320 PPAR signaling pathway
ko04146 Peroxisome
rno04146 Peroxisome
ko00120 Primary bile acid biosynthesis
rno00120 Primary bile acid biosynthesis

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6061 bile acid biosynthesis, neutral pathway

REACTOME Pathway Links

REACTOME Pathway ID Description
5954181 Beta-oxidation of pristanoyl-CoA
5953720 Bile acid and bile salt metabolism
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5953470 Peroxisomal lipid metabolism
5953930 Synthesis of bile acids and bile salts
5953931 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

Domain Information

InterPro Annotations

Accession Description
IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain
IPR012258 Acyl-CoA oxidase
IPR002655 Acyl-CoA oxidase, C-terminal
IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
IPR029320 Acyl-coenzyme A oxidase, N-terminal

UniProt Annotations

Entry Information

Gene Name
acyl-CoA oxidase 2, branched chain
Protein Entry
F1LNW3_RAT
UniProt ID
F1LNW3
Species
Rat

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data
Similarity Belongs to the acyl-CoA oxidase family

Identical and Related Proteins

Unique RefSeq proteins for LMP012979 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
404385149 RefSeq NP_665713 681 peroxisomal acyl-coenzyme A oxidase 2

Identical Sequences to LMP012979 proteins

Reference Database Accession Length Protein Name
GI:404385149 RefSeq XP_006251806.1 681 PREDICTED: peroxisomal acyl-coenzyme A oxidase 2 isoform X1 [Rattus norvegicus]
GI:404385149 RefSeq XP_006251807.1 681 PREDICTED: peroxisomal acyl-coenzyme A oxidase 2 isoform X1 [Rattus norvegicus]

Related Sequences to LMP012979 proteins

Reference Database Accession Length Protein Name
GI:404385149 GenBank EDL94160.1 738 acyl-Coenzyme A oxidase 2, branched chain, isoform CRA_a [Rattus norvegicus]
GI:404385149 GenBank EDL94161.1 686 acyl-Coenzyme A oxidase 2, branched chain, isoform CRA_b [Rattus norvegicus]
GI:404385149 RefSeq XP_006251806.1 681 PREDICTED: peroxisomal acyl-coenzyme A oxidase 2 isoform X1 [Rattus norvegicus]
GI:404385149 RefSeq XP_006251807.1 681 PREDICTED: peroxisomal acyl-coenzyme A oxidase 2 isoform X1 [Rattus norvegicus]