Gene/Proteome Database (LMPD)
LMPD ID
LMP012697
Gene ID
Species
Rattus norvegicus (Rat)
Gene Name
YKT6 v-SNARE homolog (S. cerevisiae)
Gene Symbol
Alternate Names
synaptobrevin homolog YKT6; YKT6 homolog; prenylated SNARE protein;
Chromosome
14
Map Location
14q21
EC Number
2.3.1.-
Summary
may play a role in vesicle mediated transport [RGD, Feb 2006]
Orthologs
Proteins
| synaptobrevin homolog YKT6 | |
|---|---|
| Refseq ID | NP_113880 |
| Protein GI | 162138924 |
| UniProt ID | Q5EGY4 |
| mRNA ID | NM_031692 |
| Length | 198 |
| MKLYSLSVFYKGEPKAVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSAKGSRASVKEQEYLCHVYVRSDSLAGVVIADSEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYTALDGHLSRYQNPREADPMSKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM | |
| mat_peptide: 1..195 product: Synaptobrevin homolog YKT6 experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q5EGY4.1) calculated_mol_wt: 22054 peptide sequence: MKLYSLSVFYKGEPKAVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSAKGSRASVKEQEYLCHVYVRSDSLAGVVIADSEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYTALDGHLSRYQNPREADPMSKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCC | |
Gene Information
Entrez Gene ID
Gene Name
YKT6 v-SNARE homolog (S. cerevisiae)
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005794 | IEA:UniProtKB-KW | C | Golgi apparatus |
| GO:0031201 | IDA:HGNC | C | SNARE complex |
| GO:0031410 | IEA:UniProtKB-KW | C | cytoplasmic vesicle |
| GO:0005783 | ISS:HGNC | C | endoplasmic reticulum |
| GO:0005887 | ISS:HGNC | C | integral component of plasma membrane |
| GO:0019706 | ISS:HGNC | F | protein-cysteine S-palmitoyltransferase activity |
| GO:0006888 | ISS:HGNC | P | ER to Golgi vesicle-mediated transport |
| GO:0008152 | ISS:GOC | P | metabolic process |
| GO:0015031 | IEA:UniProtKB-KW | P | protein transport |
| GO:0006904 | ISS:HGNC | P | vesicle docking involved in exocytosis |
| GO:0006903 | ISS:HGNC | P | vesicle targeting |
KEGG Pathway Links
Domain Information
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Domain | The longin domain regulates palmitoylation and membrane targeting |
| Function | Vesicular soluble NSF attachment protein receptor (v- SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity |
| Ptm | Farnesylation is required for Golgi targeting. |
| Ptm | Palmitoylated; catalyzes its own palmitoylation. Palmitoylation is required for Golgi targeting (By similarity) |
| Similarity | Belongs to the synaptobrevin family |
| Similarity | Contains 1 longin domain. {ECO:0000255|PROSITE- ProRule:PRU00231}. |
| Similarity | Contains 1 v-SNARE coiled-coil homology domain |
| Subcellular Location | Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Note=Probably cycles through vesicles between Golgi and endosomes |
| Subunit | Identified in 2 different SNARE complexes; the first one composed of GOSR1, GOSR2 and STX5 and the second one composed of BET1L, GOSR1 and STX5. |
| Tissue Specificity | Highly expressed by neurons in brain and faintly detected in spleen, lung and kidney (at protein level). Ubiquitously expressed |
Identical and Related Proteins
Unique RefSeq proteins for LMP012697 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 162138924 | RefSeq | NP_113880 | 198 | synaptobrevin homolog YKT6 |
Identical Sequences to LMP012697 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:162138924 | GenBank | AAW81771.1 | 198 | SNARE protein Ykt6 [Rattus norvegicus] |
| GI:162138924 | GenBank | EDM00327.1 | 198 | rCG35885, isoform CRA_a [Rattus norvegicus] |
| GI:162138924 | SwissProt | Q5EGY4.1 | 198 | RecName: Full=Synaptobrevin homolog YKT6; Flags: Precursor [Rattus norvegicus] |
Related Sequences to LMP012697 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:162138924 | GenBank | AAW81771.1 | 198 | SNARE protein Ykt6 [Rattus norvegicus] |
| GI:162138924 | GenBank | EDM00327.1 | 198 | rCG35885, isoform CRA_a [Rattus norvegicus] |
| GI:162138924 | SwissProt | Q5EGY4.1 | 198 | RecName: Full=Synaptobrevin homolog YKT6; Flags: Precursor [Rattus norvegicus] |