Gene/Proteome Database (LMPD)

LMPD ID
LMP012548
Gene ID
25696
Species
Rattus norvegicus (Rat)
Gene Name
very low density lipoprotein receptor
Gene Symbol
Vldlr
Alternate Names
very low-density lipoprotein receptor; VLDL-R; VLDL receptor;
Chromosome
1
Map Location
1q51
Summary
mouse homolog is a lipoprotein receptor involved in the metabolic handling of triacylglycerol [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Vldlr

Proteins

very low-density lipoprotein receptor precursor
Refseq ID NP_037287
Protein GI 293597511
UniProt ID F1LPV2
mRNA ID NM_013155
Length 873
MGTSARWALWLLLALCWAPRDSGATASGKKAKCDSSQFQCTNGRCITLLWKCDGDEDCTDGSDEKNCVKKTCAESDFVCKNGQCVPNRWQCDGDPDCEDGSDESPEQCHMRTCRINEISCGARSTQCIPESWRCDGENDCDNGEDEENCGNITCSADEFTCSSGRCVSRNFVCNGQDDCDDGSDELDCAPPTCGAHEFQCSTSSCIPLSWVCDDDADCSDQSDESLEQCGRQPVIHTKCPTSEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCRSGECIDITKVCDQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHFKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTEDIQWPNGITLDLVKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGSELATLVNNLNDAQDIIIYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPNGYNLEENGRECQSTSTPVTYSETKDVNTTDILRTSGLVPGGINVTTAVSEVSVPPKGTSAAWAILPLLLLVMAAVGGYLMWRNWQHKNMKSMNFDNPVYLKTTEEDLSIDIGRHSASVGHTYPAISVVSTDDDLA
sig_peptide: 1..27 calculated_mol_wt: 2905 peptide sequence: MGTSARWALWLLLALCWAPRDSGATAS mat_peptide: 28..873 product: very low-density lipoprotein receptor calculated_mol_wt: 93586 peptide sequence: GKKAKCDSSQFQCTNGRCITLLWKCDGDEDCTDGSDEKNCVKKTCAESDFVCKNGQCVPNRWQCDGDPDCEDGSDESPEQCHMRTCRINEISCGARSTQCIPESWRCDGENDCDNGEDEENCGNITCSADEFTCSSGRCVSRNFVCNGQDDCDDGSDELDCAPPTCGAHEFQCSTSSCIPLSWVCDDDADCSDQSDESLEQCGRQPVIHTKCPTSEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCRSGECIDITKVCDQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHFKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTEDIQWPNGITLDLVKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGSELATLVNNLNDAQDIIIYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPNGYNLEENGRECQSTSTPVTYSETKDVNTTDILRTSGLVPGGINVTTAVSEVSVPPKGTSAAWAILPLLLLVMAAVGGYLMWRNWQHKNMKSMNFDNPVYLKTTEEDLSIDIGRHSASVGHTYPAISVVSTDDDLA

Gene Information

Entrez Gene ID
25696
Gene Name
very low density lipoprotein receptor
Gene Symbol
Vldlr
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005615 IEA:Ensembl C extracellular space
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0043235 IEA:Ensembl C receptor complex
GO:0005509 IEA:InterPro F calcium ion binding
GO:0034437 IEA:Ensembl F glycoprotein transporter activity
GO:0038025 IEA:Ensembl F reelin receptor activity
GO:0030229 IEA:Ensembl F very-low-density lipoprotein particle receptor activity
GO:0000122 IEA:Ensembl P negative regulation of transcription from RNA polymerase II promoter
GO:1900006 IEA:Ensembl P positive regulation of dendrite development
GO:0045860 IEA:Ensembl P positive regulation of protein kinase activity
GO:0021517 IEA:Ensembl P ventral spinal cord development
GO:0034447 IEA:Ensembl P very-low-density lipoprotein particle clearance

Domain Information

InterPro Annotations

Accession Description
IPR001881 EGF-like calcium-binding domain
IPR018097 EGF-like calcium-binding, conserved site
IPR013032 EGF-like, conserved site
IPR000152 EGF-type aspartate/asparagine hydroxylation site
IPR000742 Epidermal growth factor-like domain
IPR000033 LDLR class B repeat
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
IPR011042 Six-bladed beta-propeller, TolB-like

UniProt Annotations

Entry Information

Gene Name
very low density lipoprotein receptor
Protein Entry
F1LPV2_RAT
UniProt ID
F1LPV2
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP012548 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
293597511 RefSeq NP_037287 873 very low-density lipoprotein receptor precursor

Identical Sequences to LMP012548 proteins

Reference Database Accession Length Protein Name
GI:293597511 RefSeq XP_006231259.1 873 PREDICTED: very low-density lipoprotein receptor isoform X1 [Rattus norvegicus]
GI:293597511 RefSeq XP_006231260.1 873 PREDICTED: very low-density lipoprotein receptor isoform X1 [Rattus norvegicus]

Related Sequences to LMP012548 proteins

Reference Database Accession Length Protein Name
GI:293597511 RefSeq XP_006231259.1 873 PREDICTED: very low-density lipoprotein receptor isoform X1 [Rattus norvegicus]
GI:293597511 RefSeq XP_006231260.1 873 PREDICTED: very low-density lipoprotein receptor isoform X1 [Rattus norvegicus]
GI:293597511 SwissProt P98166.1 873 RecName: Full=Very low-density lipoprotein receptor; Short=VLDL receptor; Short=VLDL-R; Flags: Precursor [Rattus norvegicus]